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How to get fromLyon to Santa Maria Novellaby train (Trenitalia), bus, car, plane, train (Trenitalia, TGV), or train

Find Transport to Santa Maria Novella

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There are 9 ways to get from Lyon to Santa Maria Novella by train (Trenitalia), bus, car, plane, train (Trenitalia, TGV), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    7h 2m
    €86–180

  2. Bus via Piazza Pier Della Francesca

    cheapest
    1. Take the bus from Lyon to Florence Villa Constanza Bus Stationbus bus 1501 / ...
    11h 6m
    €48–118

  3. Drive 689.8 km

    1. Drive from Lyon to Santa Maria Novellacar car 689.8 km
    7h 3m
    €108–156

  4. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    4h 24m
    €93–228

  5. Train via Turin

    1. Take the train from Lyon Part Dieu to Chambery Challes Les Eauxtrain train Ter
    2. Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain train Tgv
    3. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    8h 38m
    €92–230

  6. Bus

    1. Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus bus Itabus
    12h 37m
    €50–95

  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5h 7m
    €90–223

  8. Train to Geneva International Airport, fly to Florence Peretola Airport

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    8h 9m
    €122–312

  9. Fly Lyon–Saint Exupéry Airport to Venice Marco Polo Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Venice Marco Polo Airport (VCE)plane plane LYS - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    6h 47m
    €82–278

Lyon to Santa Maria Novella by train and foot

Calendar28Weekly Services
Duration7h 2mAverage Duration
Ticket€86Cheapest Price
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Questions & Answers

Map of how to get from Lyon to Santa Maria Novella.ExpandLaunch map view
  • Distance: 749.3 km
  • Duration: 7h 2m

What companies run services between Lyon, France and Santa Maria Novella, Italy?

You can take a train from Lyon Part Dieu to Santa Maria Novella via Milano Centrale and Firenze S.M.N. in around 7h 2m. Alternatively, FlixBus operates a bus from Lyon to Florence Villa Constanza Bus Station 5 times a day. Tickets cost €60–110 and the journey takes 10h 10m. Two other operators also service this route.

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