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How to get fromLyon to Siena Cathedralby train, bus, car, or plane

Find Transport to Siena Cathedral

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There are 10 ways to get from Lyon to Siena Cathedral by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus 131
    9h 9m
    €87–153

  2. Bus via Florence

    cheapest
    1. Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus bus Itabus
    2. Take the bus from Stazione Leopolda to SIENA-P.za SAN DOMENICObus bus 131R / ...
    14h 22m
    €46–77

  3. Bus

    1. Take the bus from Lyon to Sienabus bus 516 / ...
    11h 47m
    €65–110

  4. Drive  730.8 km

    1. Drive from Lyon to Siena Cathedralcar car 730.8 km
    8h
    €139–201

  5. Train to Geneva International Airport, fly to Florence Peretola Airport, bus

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    9h 56m
    €128–319

  6. Train, bus via Turin

    1. Take the train from Lyon Part Dieu to Torino Porta Susatrain train Fr
    2. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to SIENA-P.za SAN DOMENICObus bus 131
    9h 55m
    €91–166

  7. Fly Lyon–Saint Exupéry Airport to Fiumicino International Airport, train, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Fiumicino International Airport (FCO)plane plane LYS - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 40m
    €101–323

  8. Fly Lyon–Saint Exupéry Airport to Venice Marco Polo Airport, train, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Venice Marco Polo Airport (VCE)plane plane LYS - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 59m
    €82–314

  9. Train to Geneva International Airport, fly to Fiumicino International Airport, train, bus

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane plane GVA - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    10h 29m
    €117–328

  10. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    2. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    6h 7m
    €62–274

Lyon to Siena Cathedral by train, bus, and foot

Calendar14Weekly Services
Duration9h 9mAverage Duration
Ticket€87Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lyon to Siena Cathedral.ExpandLaunch map view
  • Distance: 819.9 km
  • Duration: 9h 9m

What companies run services between Lyon, France and Siena Cathedral, Tuscany, Italy?

FlixBus operates a bus from Lyon to Siena 5 times a week. Tickets cost €65–110 and the journey takes 11h 20m.

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Bus operators

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