There are 6 ways to get from Lyon to Sisteron by train (TGV, Trenitalia), bus, car, train (TGV, Renfe), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Les Pennes-Mirabeau
best- Take the train from Lyon Part Dieu to Aix En Provence Tgvtrain Tgv
- Take the train from Aix En Provence to Sisterontrain Ter
4h 18m€58–133Bus
cheapest- Take the bus from Lyon to Grenoblebus 766 / ...
- Take the bus from Grenoble Gare Routiere to Gapbus
- Take the bus from Gap to Sisteron Halte Routierebus
6h 36m€36–75Drive 240.7 km
- Drive from Lyon to Sisteroncar 240.7 km
2h 57m€39–56Train
- Take the train from Lyon Part Dieu to Valence Tgv Rhone-Alpes Sudtrain Tgv
- Take the train from Valence Tgv Rhone-Alpes Sud to Veynes Devoluytrain Ter
- Take the train from Veynes Devoluy to Sisterontrain Ter
5h 6m€45–103Train #2
- Take the train from Lyon Jean Mace to Valence Villetrain Ter
- Take the train from Valence Ville to Veynes Devoluytrain Ter
- Take the train from Veynes Devoluy to Sisterontrain Ter
5h 27m€49–105Train, bus
- Take the train from Lyon Part Dieu to Grenobletrain Ter
- Take the bus from Grenoble to Gapbus P24 / ...
- Take the bus from Gap to Sisteron Halte Routierebus
6h 39m€54–80
Lyon to Sisteron by train, bus, and foot
Comparing Your Travel Options
The cheapest way to get from Lyon to Sisteron is to drive which costs €35 - €60 and takes 2h 57m.
The fastest way to get from Lyon to Sisteron is to drive which takes 2h 57m and costs €35 - €60.
No, there is no direct bus from Lyon to Sisteron. However, there are services departing from Lyon and arriving at Sisteron Halte Routiere via Grenoble Gare Routiere and Gap. The journey, including transfers, takes approximately 6h 36m.
No, there is no direct train from Lyon to Sisteron. However, there are services departing from Lyon Part Dieu and arriving at Sisteron via Aix En Provence. The journey, including transfers, takes approximately 4h 18m.
The distance between Lyon and Sisteron is 427 km. The road distance is 240.7 km.
The best way to get from Lyon to Sisteron without a car is to train via Les Pennes-Mirabeau which takes 4h 18m and costs €55 - €140.
It takes approximately 4h 18m to get from Lyon to Sisteron, including transfers.
Lyon to Sisteron bus services, operated by FlixBus, depart from Lyon station.
Lyon to Sisteron train services, operated by TGV inOui, depart from Lyon Part Dieu station.
The best way to get from Lyon to Sisteron is to train via Les Pennes-Mirabeau which takes 4h 18m and costs €55 - €140. Alternatively, you can bus, which costs €35 - €80 and takes 6h 36m.
What companies run services between Lyon, France and Sisteron, Provence-Alpes-Côte d'Azur, France?
You can take a train from Lyon Part Dieu to Sisteron via Aix En Provence Tgv, Gare Aix TGV, Gare Routière, and Aix En Provence in around 4h 18m. Alternatively, you can take a bus from Lyon to Sisteron Halte Routiere via Grenoble, Grenoble Gare Routiere, and Gap in around 6h 36m.
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Aix En Provence Tgv
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €60–90
- Website
- TGV inOui
Train from Lyon Part Dieu to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €20–30
- Website
- TGV inOui
Train from Lyon Part Dieu to Grenoble
- Ave. Duration
- 1h 11m
- Frequency
- 4 times a week
- Estimated price
- €26–40
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Aix En Provence Tgv
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- €50–90
- Website
- Oui.SNCF
Train from Aix En Provence to Sisteron
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- €19–35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 35 min
- Frequency
- 4 times a day
- Estimated price
- €17–30
- Website
- Oui.SNCF
Train from Valence Tgv Rhone-Alpes Sud to Veynes Devoluy
- Ave. Duration
- 2h 19m
- Frequency
- Every 2 hours
- Estimated price
- €24–45
- Website
- Oui.SNCF
Train from Veynes Devoluy to Sisteron
- Ave. Duration
- 42 min
- Frequency
- Every 3 hours
- Estimated price
- €8–15
- Website
- Oui.SNCF
Train from Lyon Jean Mace to Valence Ville
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- Oui.SNCF
Train from Valence Ville to Veynes Devoluy
- Ave. Duration
- 2h 8m
- Frequency
- Every 2 hours
- Estimated price
- €23–40
- Website
- Oui.SNCF
Train from Veynes Devoluy to Sisteron
- Ave. Duration
- 42 min
- Frequency
- Every 3 hours
- Estimated price
- €8–15
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Grenoble
- Ave. Duration
- 1h 23m
- Frequency
- Every 30 minutes
- Estimated price
- €22–40
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Aix En Provence Tgv
- Ave. Duration
- 1h 32m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Aix En Provence to Sisteron
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- €29–40
- Website
- Zou! Lignes Express Régionales
Train from Valence Tgv Rhone-Alpes Sud to Veynes Devoluy
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a day
- Estimated price
- €35–55
- Website
- Zou! Lignes Express Régionales
Train from Veynes Devoluy to Sisteron
- Ave. Duration
- 42 min
- Frequency
- 5 times a day
- Estimated price
- €13–18
- Website
- Zou! Lignes Express Régionales
Train from Lyon Jean Mace to Valence Ville
- Ave. Duration
- 1h 6m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Zou! Lignes Express Régionales
Train from Valence Ville to Veynes Devoluy
- Ave. Duration
- 2h 11m
- Frequency
- 5 times a day
- Estimated price
- €35–50
- Website
- Zou! Lignes Express Régionales
Train from Veynes Devoluy to Sisteron
- Ave. Duration
- 42 min
- Frequency
- 5 times a day
- Estimated price
- €13–18
- Website
- Zou! Lignes Express Régionales
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Lyon Part Dieu to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 33 min
- Frequency
- 4 times a day
- Estimated price
- €12–19
- Website
- Renfe Viajeros
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Lyon Part Dieu to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- €18–28
- Website
- Belgian Railways
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- €9–14
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- BlaBlaCar Bus
Bus from Grenoble Gare Routiere to Gap
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- €30–50
- Website
- SNCF Bus
Bus from Gap to Sisteron Halte Routiere
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- €8–12
- Website
- SNCF Bus
Bus from Gap to Sisteron Halte Routiere
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- €10–14
- Website
- SNCF Bus
- Phone
- +33 4 8000 7000
- [email protected]
- Website
- cars Région Isère
Bus from Grenoble Gare Routiere to Gap
- Ave. Duration
- 2h 38m
- Frequency
- 4 times a day
- Estimated price
- €21–28
- Schedules at
- cars Région Isère
Bus from Grenoble to Gap
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- €21–28
- Schedules at
- cars Région Isère
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Bus from Grenoble to Gap
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Website
- Zou! Lignes Express Régionales
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Booking & Getting There
Lyon to Sisteron bus services, operated by FlixBus, arrive at Grenoble station.
Lyon to Sisteron train services, operated by TGV inOui, arrive at Aix En Provence Tgv station.
Yes, the driving distance between Lyon to Sisteron is 241 km. It takes approximately 2h 57m to drive from Lyon to Sisteron.
Book your Lyon to Sisteron train tickets online with Omio.
There are 313+ hotels available in Sisteron.



































