There are 9 ways to get from Lyss to Florence by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Bern to Brigtrain Ic8 / ...
- Take the bus from Domodossola to Rho Fiera Milanobus Re4
- Take the train from Milano Rogoredo to Firenze Santa Maria Novellatrain
8h 26mBus
cheapest- Take the bus from Payerne to Florence Villa Constanza Bus Stationbus
15h 14m€56–75Bus via Genoa
- Take the bus from Bern to Genoabus FlixBus N506
- Take the bus from Genoa to Florence Villa Constanza Bus Stationbus 510 / ...
12h 30m€64–100Drive 645 km
- Drive from Lyss to Florencecar 645 km
6h 39m€135–195Train to Zurich Airport, fly to Florence Peretola Airport
- Take the train from Bern to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
5h 29m€142–384Train via Brig
- Take the train from Bern to Brigtrain Ic8 / ...
- Take the train from Domodossola to Rho-Fiera Milanotrain Re
- Take the train from Milano Rogoredo to Firenze Santa Maria Novellatrain
9h 5m€89–151Train
- Take the train from Bern to Locarnotrain Ic
- Take the train from Locarno to Milano Centraletrain
- Take the train from Milano Centrale to Firenze Santa Maria Novellatrain
9h 38m€160–267Train to Basel, fly to Florence Peretola Airport
- Take the train from Biel/Bienne to Basel SBBtrain
- Fly from Basel (BSL) to Florence Peretola Airport (FLR)plane BSL - FLR
7h 41m€120–308Train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Bern to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
6h 14m€135–393
Lyss to Florence by bus
Comparing Your Travel Options
The cheapest way to get from Lyss to Florence is to bus which costs €55 - €75 and takes 15h 14m.
The fastest way to get from Lyss to Florence is to train and fly which takes 5h 29m and costs €140 - €390.
No, there is no direct bus from Lyss to Florence station. However, there are services departing from Lyss, Mühleplatz and arriving at Florence Villa Constanza Bus Station via Bern and Genoa. The journey, including transfers, takes approximately 12h 30m.
No, there is no direct train from Lyss to Florence. However, there are services departing from Lyss and arriving at Firenze Santa Maria Novella via Bern, Brig, Domodossola and Milano Rogoredo. The journey, including transfers, takes approximately 9h 5m.
The distance between Lyss and Florence is 603 km. The road distance is 645 km.
The best way to get from Lyss to Florence without a car is to train and bus which takes 8h 26m and costs .
It takes approximately 8h 26m to get from Lyss to Florence, including transfers.
Lyss to Florence bus services, operated by FlixBus, depart from Bern station.
Lyss to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Bern station.
The best way to get from Lyss to Florence is to bus via Genoa which takes 12h 30m and costs €60 - €100. Alternatively, you can train via Brig, which costs €85 - €160 and takes 9h 5m.
What companies run services between Lyss, Switzerland and Florence, Italy?
You can take a bus from Lyss, Mühleplatz to Florence Villa Constanza Bus Station via Bern, Neufeld P+R, Bern, and Genoa in around 12h 30m. Alternatively, you can take a train from Lyss to Firenze Santa Maria Novella via Bern, Brig, Domodossola, and Milano Rogoredo in around 9h 5m.
- Website
- lufthansa.com
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €160–490
Flights from Basel to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €190–600
Flights from Basel to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- €70–600
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Sunday and Friday
- Estimated price
- €85–270
- Website
- swiss.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €85–370
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Sunday and Friday
- Estimated price
- €85–270
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €85–430
- Website
- ita-airways.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €85–370
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Sunday and Friday
- Estimated price
- €85–270
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €85–430
- Website
- austrian.com
Flights from Basel to Florence Peretola Airport via Vienna
- Ave. Duration
- 4h 5m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €100–430
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Sunday and Friday
- Estimated price
- €85–270
- Website
- airdolomiti.it
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Friday and Saturday
- Estimated price
- €160–490
Train from Bern to Brig
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bern to Zürich Flughafen
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bern to Brig
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bern to Locarno
- Ave. Duration
- 2h 57m
- Frequency
- Once a week
- Estimated price
- €85–140
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Locarno to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Biel/Bienne to Basel SBB
- Ave. Duration
- 1h 7m
- Frequency
- Hourly
- Estimated price
- €24–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bern to Zürich Flughafen
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Rogoredo to Firenze Santa Maria Novella
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Milano Rogoredo to Firenze Santa Maria Novella
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Milano Centrale to Firenze Santa Maria Novella
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 41 min
- Frequency
- 5 times a day
- Estimated price
- €10–18
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Domodossola to Rho-Fiera Milano
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €13–19
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
- Phone
- +41 58 327 32 71
- Website
- BLS AG
Train from Biel/Bienne to Basel SBB
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €14–20
- Website
- BLS AG
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €10–18
- Website
- Trenitalia Intercity
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Bus from Domodossola to Rho Fiera Milano
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Website
- Trenord
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Bern to Genoa
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- €40–65
- Website
- Flixbus
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- €20–30
- Website
- Flixbus
- Phone
- +39 0824 46304
- [email protected]
- Website
- sellitto.com
Bus from Payerne to Florence Villa Constanza Bus Station
- Ave. Duration
- 12h 30m
- Frequency
- Twice a week
- Estimated price
- €50–65
- Schedules at
- sellitto.com
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Booking & Getting There
Lyss to Florence bus services, operated by FlixBus, arrive at Genoa station.
Lyss to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Brig station.
Yes, the driving distance between Lyss to Florence is 645 km. It takes approximately 6h 39m to drive from Lyss to Florence.
There are 8100+ hotels available in Florence.

































