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How to get fromMachala to Santo Domingo, Ecuadorby bus, car, taxi, or plane

Find Transport to Santo Domingo, Ecuador

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There are 9 ways to get from Machala to Santo Domingo, Ecuador by bus, car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Machala

    best
    1. Take the bus from Machala to Terminal Terrestre de Guayaquilbus bus Machala
    2. Take the bus from Terminal Terrestre de Guayaquil to Santo Domingo de los Coloradosbus bus Guayaquil / ...
    8h 12m
    $17–39

  2. Bus #2

    cheapest
    1. Take the bus from Santa Rosa to Santo Domingo de los Coloradosbus bus Macará
    10h 28m
    $14–22

  3. Drive 412.2 km

    1. Drive from Machala to Santo Domingo, Ecuadorcar car 412.2 km
    6h 10m
    $24–34

  4. Taxi to José Joaquín De Olmedo International Airport, fly, bus

    1. Take the taxi from Machala to Guayaquil-Airport-GYEtaxi taxi
    2. Fly from José Joaquín De Olmedo International Airport (GYE) to Mariscal Sucre International Airport (UIO)plane plane GYE - UIO
    3. Take the bus from Quito Terminal Carcelén to Santo Domingo de los Coloradosbus bus
    7h 8m
    $199–289

  5. Bus

    1. Take the bus from Machala to Terminal Terrestre de Guayaquilbus bus Cariamanga
    2. Take the bus from Terminal Terrestre de Guayaquil to Santo Domingo de los Coloradosbus bus Guayaquil / ...
    9h 27m
    $16–32

  6. Bus #3

    1. Take the bus from Machala to Cuencabus bus Cuenca / ...
    2. Take the bus from Cuenca to Santo Domingo de los Coloradosbus bus Cuenca
    12h 30m
    $19–32

  7. Fly from Santa Rosa Regional Airport, bus

    1. Fly from Santa Rosa Regional Airport (ETR) to Mariscal Sucre International Airport (UIO)plane plane ETR - UIO
    2. Take the bus from Quito Terminal Carcelén to Santo Domingo de los Coloradosbus bus
    6h 17m
    $177–508

  8. Bus to Cuenca, fly, bus

    1. Take the bus from Machala to Cuencabus bus
    2. Fly from Cuenca (CUE) to Mariscal Sucre International Airport (UIO)plane plane CUE - UIO
    3. Take the bus from Quito Terminal Carcelén to Santo Domingo de los Coloradosbus bus
    8h 38m
    $104–247

  9. Bus to Loja, fly, bus

    1. Take the bus from Machala to Catamayobus bus
    2. Fly from Loja (LOH) to Mariscal Sucre International Airport (UIO)plane plane LOH - UIO
    3. Take the bus from Quito Terminal Carcelén to Santo Domingo de los Coloradosbus bus
    7h 43m
    $176–206

José Joaquín De Olmedo International Airport (GYE) to Mariscal Sucre International Airport (UIO) flights

Calendar104Weekly Planes
Duration53 minAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Machala to Santo Domingo, Ecuador.ExpandLaunch map view
  • Distance: 474.4 km
  • Duration: 8h 12m

What companies run services between Machala, Ecuador and Santo Domingo, Ecuador?

You can take a vehicle from Machala to Santo Domingo de los Colorados via Machala and Terminal Terrestre de Guayaquil in around 8h 12m.

Airlines
Bus operators
Other operators

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