There are 6 ways to get from Macomb to Cape Girardeau by train, bus, taxi, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Macomb Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg Amtrak Station to Springfieldbus
- Take the train from Springfield to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
9h 47m$117–222Drive 261.6 mi
cheapest- Drive from Macomb to Cape Girardeaucar 261.6 mi
5h 24m$48–69Train, taxi
- Take the train from Macomb Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Carbondaletrain
- Take the taxi from Carbondale to Cape Girardeautaxi
11h 2m$275–504Taxi, fly to Cape Girardeau Municipal Airport
- Take the taxi from Macomb to Burlington Municipal Airport (BRL)taxi
- Fly from Burlington Municipal Airport (BRL) to Cape Girardeau Municipal Airport (CGI)plane BRL - CGI
12h 50m$271–717Train, bus via Springfield
- Take the train from Macomb Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg Amtrak Station to Springfieldbus
- Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
10h$104–185Taxi, fly to Williamson County Regional Airport
- Take the taxi from Macomb to Burlington Municipal Airport (BRL)taxi
- Fly from Burlington Municipal Airport (BRL) to Williamson County Regional Airport (MWA)plane BRL - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
6h 58m$388–849
Burlington Municipal Airport (BRL) to Cape Girardeau Municipal Airport (CGI) flights
Questions & Answers
The cheapest way to get from Macomb to Cape Girardeau is to drive which costs $45 - $70 and takes 5h 24m.
The fastest way to get from Macomb to Cape Girardeau is to drive which takes 5h 24m and costs $45 - $70.
The distance between Macomb and Cape Girardeau is 420 miles. The road distance is 263.1 miles.
The best way to get from Macomb to Cape Girardeau without a car is to train and bus which takes 9h 47m and costs $110 - $230.
It takes approximately 9h 47m to get from Macomb to Cape Girardeau, including transfers.
Yes, the driving distance between Macomb to Cape Girardeau is 263 miles. It takes approximately 5h 24m to drive from Macomb to Cape Girardeau.
There are 17+ hotels available in Cape Girardeau.
What companies run services between Macomb, IL, USA and Cape Girardeau, MO, USA?
There is no direct connection from Macomb to Cape Girardeau. However, you can take the train to Galesburg Amtrak Station, walk to Galesburg Amtrak Station, take the bus to Springfield, walk to Springfield, take the train to St. Louis, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Cape Girardeau. Alternatively, you can take the train to Chicago Union Station, take the train to Carbondale, then take the taxi to Cape Girardeau.
- Website
- contouraviation.com
Flights from Burlington Municipal Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 21h 10m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–600
Flights from Burlington Municipal Airport to Cape Girardeau Municipal Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 11h 25m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $130–550
Flights from Burlington Municipal Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 35m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Macomb Station to Galesburg Amtrak Station
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $28–60
- Website
- Amtrak
Train from Springfield to St. Louis
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $30–65
- Website
- Amtrak
Train from Macomb Station to Chicago Union Station
- Ave. Duration
- 3h 32m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- Amtrak
Train from Chicago Union Station to Carbondale
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $95–210
- Website
- Amtrak
Train from Macomb Station to Galesburg Amtrak Station
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $28–60
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Galesburg Amtrak Station to Springfield
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Amtrak
Bus from Galesburg Amtrak Station to Springfield
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Springfield SMTD Transfer Center to St Louis Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 9m
- Estimated price
- $100–160
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
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