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How to get fromMacomb to Louisvilleby train, bus, car, plane, or taxi

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There are 8 ways to get from Macomb to Louisville by train, bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Macomb Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 5m
    $85–178

  2. Drive 373.1 mi

    cheapest
    1. Drive from Macomb to Louisvillecar car 373.1 mi
    6h 55m
    $69–99

  3. Train, bus via Chicago (Amtrak)

    1. Take the train from Macomb Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    12h 51m
    $162–339

  4. Train to Chicago Midway International Airport, fly

    1. Take the train from Macomb Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    7h 46m
    $166–725

  5. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Macomb Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    8h 17m
    $148–592

  6. Train, bus to Peoria International Airport, fly

    1. Take the train from Macomb Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg Amtrak Station to Peoria Amtrak Stationbus bus
    3. Fly from Peoria International Airport (PIA) to Louisville International Airport (SDF)plane plane PIA - SDF
    9h 18m
    $125–554

  7. Taxi to Burlington Municipal Airport, fly

    1. Take the taxi from Macomb to Burlington Municipal Airport (BRL)taxi taxi
    2. Fly from Burlington Municipal Airport (BRL) to Louisville International Airport (SDF)plane plane BRL - SDF
    7h 4m
    $204–632

  8. Train to Quincy Regional Airport, fly

    1. Take the train from Macomb Station to Quincy Amtrak Stationtrain train
    2. Fly from Quincy Regional Airport (UIN) to Louisville International Airport (SDF)plane plane UIN - SDF
    8h 15m
    $149–590

Macomb to Louisville by train and bus

Calendar7Weekly Services
Duration10h 5mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Macomb to Louisville.ExpandLaunch map view
  • Distance: 458.5 mi
  • Duration: 10h 5m

What companies run services between Macomb, IL, USA and Louisville, KY, USA?

There is no direct connection from Macomb to Louisville. However, you can take the train to Galesburg Amtrak Station, walk to Galesburg, take the bus to Indianapolis Union Station, then take the bus to Louisville, KY. Alternatively, you can take a train from Macomb Station to Louisville, KY via Chicago Union Station, Indianapolis, and Indianapolis Union Station in around 12h 51m.

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