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How to get fromMacomb to Mayo Clinicby train, bus, car, plane, or taxi

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There are 7 ways to get from Macomb to Mayo Clinic by train, bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Madison

    best
    1. Take the train from Macomb Station to La Grange Amtraktrain train
    2. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    13h 26m
    $150–285

  2. Drive 313.1 mi

    cheapest
    1. Drive from Macomb to Mayo Cliniccar car 313.1 mi
    6h 4m
    $58–83

  3. Train, bus

    1. Take the train from Macomb Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    14h 36m
    $238–475

  4. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Macomb Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    8h 15m
    $123–500

  5. Train, bus via Des Moines

    1. Take the train from Macomb Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg to Des Moinesbus bus
    3. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    4. Take the bus from St. Paul to Rochesterbus bus
    15h 39m
    $121–228

  6. Train, bus to Peoria International Airport, fly

    1. Take the train from Macomb Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg Amtrak Station to Peoria Amtrak Stationbus bus
    3. Fly from Peoria International Airport (PIA) to Rochester (RST)plane plane PIA - RST
    9h 25m
    $95–451

  7. Taxi to Burlington Municipal Airport, fly

    1. Take the taxi from Macomb to Burlington Municipal Airport (BRL)taxi taxi
    2. Fly from Burlington Municipal Airport (BRL) to Rochester (RST)plane plane BRL - RST
    9h 10m
    $174–519

Macomb to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration13h 26mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from Macomb to Mayo Clinic.ExpandLaunch map view
  • Distance: 588 mi
  • Duration: 13h 26m

What companies run services between Macomb, IL, USA and Mayo Clinic, MN, USA?

There is no direct connection from Macomb to Mayo Clinic. However, you can take the train to La Grange Amtrak, walk to La Grange/Burlington Ave., take the line 330 bus to O'Hare MMF Bay 8, take the bus to 250 N. Lake St - Madison UW Campus, walk to Madison, take the bus to Rochester, then walk to Mayo Clinic. Alternatively, you can take a train from Macomb Station to Mayo Clinic via Chicago Union Station, St. Paul-Minneapolis, St. Paul, and Rochester in around 14h 36m.

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