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How to get fromMadison Airport (MSN) to Des Moinesby plane, bus (Greyhound), rideshare, car, bus (Flixbus, Greyhound), bus, or train

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There are 7 ways to get from Madison Airport (MSN) to Des Moines by plane, bus (Greyhound), rideshare, car, bus (Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Des Moines (DSM)plane plane MSN - DSM
    3h 44m
    $146–772

  2. Drive 280.5 mi

    cheapest
    1. Drive from Madison Airport (MSN) to Des Moinescar car 280.5 mi
    5h 19m
    $52–74

  3. Bus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    12h 55m
    $78–162

  4. Airport Transfer

    1. Take the rideshare from Madison-MSN to Des Moinesrideshare rideshare 280.5 mi
    5h 19m

  5. Bus via Saint Paul

    1. Take the bus from Madison to St. Paulbus bus Jefferson 966 / ...
    2. Take the bus from St. Paul to Des Moinesbus bus Jefferson Lines 805
    13h 5m
    $107–172

  6. Bus via Minneapolis Airport (MSP)

    1. Take the bus from Madison, WI-Lake St. to Mall of America - IKEA - Bloomingtonbus bus Madison
    2. Take the bus from Minneapolis-St. Paul to Des Moinesbus bus Jefferson Lines 803
    13h 12m
    $124–169

  7. Bus, train

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    15h 5m
    $121–255

Madison Airport (MSN) to Des Moines by bus and foot

Calendar19Weekly Services
Duration12h 55mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Madison Airport (MSN) to Des Moines.ExpandLaunch map view
  • Distance: 252.5 mi
  • Duration: 3h 44m

What companies run services between Madison Airport (MSN), USA and Des Moines, IA, USA?

United Airlines, American Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Airport at Terminal Door 6 to Des Moines via University at East Campus, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 12h 55m.

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