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How to get fromMadison to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Madison to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Jackson/Vicksburg (JAN) to Louisville International Airport (SDF)plane plane JAN - SDF
    5h 33m
    $155–575

  2. Drive 550.1 mi

    cheapest
    1. Drive from Madison to Louisvillecar car 550.1 mi
    9h 59m
    $101–145

  3. Bus

    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    13h 14m
    $143–243

  4. Fly to Blue Grass Airport, drive

    1. Fly from Jackson/Vicksburg (JAN) to Blue Grass Airport (LEX)plane plane JAN - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 19m
    $232–901

  5. Bus via Preston @ Vim

    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    15h 24m
    $143–321

Jackson/Vicksburg (JAN) to Louisville International Airport (SDF) flights

Calendar89Weekly Planes
Duration5h 27mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Madison to Louisville.ExpandLaunch map view
  • Distance: 497.1 mi
  • Duration: 5h 33m

What companies run services between Madison, MS, USA and Louisville, KY, USA?

Delta, American Airlines, and two other airlines fly from Jackson/Vicksburg (JAN) to Louisville International Airport (SDF) hourly. Alternatively, you can take a vehicle from Madison to Louisville, KY via Jackson, Memphis Bus Station, and Nashville in around 13h 14m.

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Bus operators

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