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How to get fromMadison to St. Louisby plane, bus (Greyhound), train, bus, or car

Find Transport to St. Louis

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There are 4 ways to get from Madison to St. Louis by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Jackson/Vicksburg (JAN) to Lambert–St. Louis International Airport (STL)plane plane JAN - STL
    4h 27m
    $172–635

  2. Drive 478.3 mi

    cheapest
    1. Drive from Madison to St. Louiscar car 478.3 mi
    7h 42m
    $88–127

  3. Bus

    1. Take the bus from Jackson to St Louis Bus Stationbus bus Greyhound US1173
    10h 24m
    $163–223

  4. Train, bus

    1. Take the train from Jackson to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    12h 52m
    $208–403

Jackson/Vicksburg (JAN) to Lambert–St. Louis International Airport (STL) flights

Calendar78Weekly Planes
Duration5h 18mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Madison to St. Louis.ExpandLaunch map view
  • Distance: 475.8 mi
  • Duration: 4h 27m

What companies run services between Madison, MS, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and two other airlines fly from Jackson/Vicksburg (JAN) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, Greyhound USA operates a bus from Jackson to St Louis Bus Station once daily. Tickets cost $80–160 and the journey takes 10h 5m. Jefferson Lines also services this route once daily.

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