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How to get fromMadison to Knoxvilleby bus, plane, or car

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There are 5 ways to get from Madison to Knoxville by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, line 53 bus to Memphis, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Jackson to Memphis - Summer Avebus bus
    2. Take the bus from SUMMER AVENUE at WHITE STATION ROAD to William Hudson Transit Centerbus bus
    3. Fly from Memphis (MEM) to Mcghee Tyson Airport (TYS)plane plane MEM - TYS
    6h 33m
    $212–885

  2. Drive 309.3 mi

    cheapest
    1. Drive from Madison to Knoxvillecar car 309.3 mi
    5h 11m
    $57–82

  3. Bus

    1. Take the bus from Jackson to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis - Summer Ave to New Yorkbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    38h 37m
    $342–473

  4. Fly Mc Kellar-Sipes Regional Airport to Mcghee Tyson Airport

    1. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Mcghee Tyson Airport (TYS)plane plane MKL - TYS
    5h 5m
    $215–828

  5. Fly Mc Kellar-Sipes Regional Airport to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MKL - ATL
    2. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    6h 6m
    $240–582

Memphis (MEM) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration2h 37mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from Madison to Knoxville.ExpandLaunch map view
  • Distance: 451.4 mi
  • Duration: 6h 33m

What companies run services between Madison, TN, USA and Knoxville, TN, USA?

You can take a bus from Court Square at Main Street to Knoxville via Jackson Plaza, Lou’s Crawfish, Jackson, Memphis - Summer Ave, New York, and Knoxville in around 38h 37m. Alternatively, Key Lime, Delta, and United Airlines fly from Mc Kellar-Sipes Regional Airport (MKL) to Mcghee Tyson Airport (TYS) once daily.

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