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How to get fromMadison to Cape Girardeauby plane, taxi, bus, train, car, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Madison to Cape Girardeau by plane, taxi, bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Dane County Regional Airport-Truax Field to Williamson County Regional Airport, taxi

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Williamson County Regional Airport (MWA)plane plane MSN - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    6h 27m
    $207–642

  2. Drive  455.4 mi

    cheapest
    1. Drive from Madison to Cape Girardeaucar car 455.4 mi
    8h 1m
    $84–120

  3. Bus, train, taxi

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carbondaletrain train
    4. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    11h 34m
    $222–400

  4. Bus, taxi

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Chicago to Anna - Shellbus bus
    3. Take the taxi from Anna - Shell to Cape Girardeautaxi taxi
    12h 20m
    $169–238

  5. Bus to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, taxi

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    3. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    6h 32m
    $234–430

  6. Bus to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    3. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    6h 51m
    $209–510

  7. Bus to General Mitchell International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h 7m
    $528–929

  8. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    12h 55m
    $120–270

  9. Bus, train via Milwaukee

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    4. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    12h 59m
    $136–304

  10. Bus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    14h 11m
    $95–175

Dane County Regional Airport-Truax Field (MSN) to Williamson County Regional Airport (MWA) flights

Calendar35Weekly Planes
Duration5h 59mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Madison to Cape Girardeau.ExpandLaunch map view
  • Distance: 437.1 mi
  • Duration: 6h 27m

What companies run services between Madison, WI, USA and Cape Girardeau, MO, USA?

You can take a bus from 250 N. Lake St - Madison UW Campus to Cape Girardeau via W Jackson Blvd, after S Clinton St, Chicago Bus Station, St Louis Bus Station, and Cape Girardeau in around 14h 11m.

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