There are 12 ways to get from Madison to Cape Girardeau by plane, taxi, bus, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Dane County Regional Airport-Truax Field to Williamson County Regional Airport, taxi
best- Fly from Dane County Regional Airport-Truax Field (MSN) to Williamson County Regional Airport (MWA)plane MSN - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
6h 35m$192–532Drive 455.3 mi
cheapest- Drive from Madison to Cape Girardeaucar 455.3 mi
8h 1m$84–120Bus, train, taxi
- Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Carbondaletrain
- Take the taxi from Carbondale to Cape Girardeautaxi
11h 34m$335–515Bus, taxi
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus
- Take the bus from Chicago to Anna - Shellbus
- Take the taxi from Anna - Shell to Cape Girardeautaxi
12h 16m$169–238Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane ORD - CGI
5h 47m$147–488Bus to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, taxi
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane ORD - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
6h 43m$234–420Bus to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane ORD - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi
6h 59m$204–500Fly Dane County Regional Airport-Truax Field to Cape Girardeau Municipal Airport
- Fly from Dane County Regional Airport-Truax Field (MSN) to Cape Girardeau Municipal Airport (CGI)plane MSN - CGI
6h 22m$135–580Bus to General Mitchell International Airport, fly to Lambert–St. Louis International Airport, bus
- Take the bus from Madison, WI-Lake St. to Mitchell Airportbus
- Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane MKE - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
8h 7m$529–923Bus, train
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
12h 55m$201–334Bus, train via Milwaukee
- Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
12h 59m$240–393Bus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
14h 11m$96–169
Dane County Regional Airport-Truax Field (MSN) to Williamson County Regional Airport (MWA) flights
Comparing Your Travel Options
The cheapest way to get from Madison to Cape Girardeau is to drive which costs $80 - $120 and takes 8h 1m.
The fastest way to get from Madison to Cape Girardeau is to bus and fly which takes 5h 47m and costs $140 - $490.
No, there is no direct bus from Madison to Cape Girardeau. However, there are services departing from 250 N. Lake St - Madison UW Campus and arriving at Cape Girardeau via Chicago Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 14h 11m.
The distance between Madison and Cape Girardeau is 440 miles. The road distance is 457.9 miles.
The best way to get from Madison to Cape Girardeau without a car is to bus and train and taxi which takes 11h 34m and costs $330 - $550.
It takes approximately 6h 35m to get from Madison to Cape Girardeau, including transfers.
Madison to Cape Girardeau bus services, operated by Rockland Coaches, depart from 250 N. Lake St - Madison UW Campus station.
The best way to get from Madison to Cape Girardeau is to fly which takes 6h 22m and costs $130 - $600. Alternatively, you can bus, which costs $95 - $170 and takes 14h 11m.
Madison to Cape Girardeau bus services, operated by Rockland Coaches, arrive at W Jackson Blvd, after S Clinton St station.
Yes, the driving distance between Madison to Cape Girardeau is 458 miles. It takes approximately 8h 1m to drive from Madison to Cape Girardeau.
What companies run services between Madison, WI, USA and Cape Girardeau, MO, USA?
United Airlines, Corporate Flight Management Inc, and American Airlines fly from Dane County Regional Airport-Truax Field (MSN) to Cape Girardeau Municipal Airport (CGI) 4 times a day. Alternatively, you can take a bus from 250 N. Lake St - Madison UW Campus to Cape Girardeau via W Jackson Blvd, after S Clinton St, Chicago Bus Station, St Louis Bus Station, and Cape Girardeau in around 14h 11m.
- Website
- southwest.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $85–600
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 13m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $90–600
- Website
- aa.com
Flights from Dane County Regional Airport-Truax Field to Williamson County Regional Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $60–370
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $45–300
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $100–410
Flights from Dane County Regional Airport-Truax Field to Cape Girardeau Municipal Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $140–600
Flights from Dane County Regional Airport-Truax Field to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 58m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- united.com
Flights from Chicago O'Hare International Airport to Barkley Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $40–280
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Carbondale
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–270
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- +1 414-266-4409
- [email protected]
- Website
- Badger Bus
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–30
- Website
- Badger Bus
Bus from Madison, WI-Lake St. to Mitchell Airport
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $24–35
- Website
- Badger Bus
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–30
- Website
- Badger Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–20
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–20
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $29–40
- Book at
- Jefferson Lines
- Adult
- $29–40
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $29–40
- Book at
- Jefferson Lines
- Adult
- $29–40
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Madison, WI-Lake St. to Mitchell Airport
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $12–20
- Schedules at
- Flixbus USA
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
- Phone
- 920 496 3600
- Website
- example.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $19–22
- Schedules at
- golamers.com
Bus from Madison, WI-Lake St. to Mitchell Airport
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $21–24
- Schedules at
- golamers.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $19–22
- Schedules at
- golamers.com
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Chicago to Anna - Shell
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $70–90
- Schedules at
- Tornado Bus Company
- Adult
- $70–90
- Ave. Duration
- 1h 7m
- Estimated price
- $70–170
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
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