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How to get fromMadison to Florenceby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Madison to Florence by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Florence Regional Airport (FLO)plane plane MSN - FLO
    6h 33m
    $122–615

  2. Bus via Columbus

    cheapest
    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Florence Bus Stationbus bus
    28h 32m
    $120–270

  3. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    34h 14m
    $348–803

  4. Drive  976.9 mi

    1. Drive from Madison to Florencecar car 976.9 mi
    18h 18m
    $179–258

  5. Bus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    28h 32m
    $171–326

Madison to Florence by bus and foot

Calendar7Weekly Services
Duration28h 32mAverage Duration
Ticket$120Cheapest Price
See schedules

Questions & Answers

Map of how to get from Madison to Florence.ExpandLaunch map view
  • Distance: 815.3 mi
  • Duration: 6h 33m

What companies run services between Madison, WI, USA and Florence, SC, USA?

American Airlines flies from Dane County Regional Airport-Truax Field (MSN) to Florence Regional Airport (FLO) every 4 hours. Alternatively, you can take a bus from 250 N. Lake St - Madison UW Campus to Florence Bus Station via W Jackson Blvd, after S Clinton St, Chicago, Columbus, Charlotte Bus Station, and Camden in around 28h 32m.

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