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How to get fromMadison to Florenceby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 5 ways to get from Madison to Florence by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Florence Regional Airport (FLO)plane plane MSN - FLO
    7h 25m
    $87–435

  2. Bus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    28h 32m
    $186–326

  3. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    34h 14m
    $661–1,151

  4. Drive  976.8 mi

    1. Drive from Madison to Florencecar car 976.8 mi
    18h 18m
    $179–258

  5. Bus via Columbus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago to Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Florence Bus Stationbus bus
    28h 32m
    $122–265

Madison to Florence by bus and foot

Calendar14Weekly Services
Duration28h 32mAverage Duration
Ticket$186Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madison to Florence.ExpandLaunch map view
  • Distance: 815.3 mi
  • Duration: 7h 25m

What companies run services between Madison, WI, USA and Florence, SC, USA?

American Airlines flies from Dane County Regional Airport-Truax Field (MSN) to Florence Regional Airport (FLO) 5 times a day. Alternatively, you can take a bus from 250 N. Lake St - Madison UW Campus to Florence Bus Station via W Jackson Blvd, after S Clinton St, Chicago Bus Station, and Atlanta Bus Station in around 28h 32m.

Airlines
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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

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