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How to get fromMadison to Florida Keysby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Florida Keys

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There are 6 ways to get from Madison to Florida Keys by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Dane County Regional Airport-Truax Field

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Key West International Airport (EYW)plane plane MSN - EYW
    9h 22m
    $169–516

  2. Bus

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 2h
    $350–555

  3. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 9h
    $1,169–1,919

  4. Drive  1,603.8 mi

    1. Drive from Madison to Florida Keyscar car 1,603.8 mi
    28h 43m
    $293–423

  5. Bus to General Mitchell International Airport, fly

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Key West International Airport (EYW)plane plane MKE - EYW
    10h 41m
    $208–676

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Key West International Airport (EYW)plane plane ORD - EYW
    10h 13m
    $171–474

Madison to Florida Keys by bus and foot

Calendar4Weekly Services
Duration2d 2hAverage Duration
Ticket$350Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madison to Florida Keys.ExpandLaunch map view
  • Distance: 1,382.8 mi
  • Duration: 9h 22m

What companies run services between Madison, WI, USA and Florida Keys, FL, USA?

Delta, American Airlines, and United Airlines fly from Dane County Regional Airport-Truax Field (MSN) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from 250 N. Lake St - Madison UW Campus to Florida Keys via W Jackson Blvd, after S Clinton St, Chicago Bus Station, Washington Union Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 2h.

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