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How to get fromMadison to Jeffersonvilleby bus (Flixbus, Greyhound, Amtrak), bus, train, car, plane, or bus (Amtrak)

Find Transport to Jeffersonville

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There are 11 ways to get from Madison to Jeffersonville by bus (Flixbus, Greyhound, Amtrak), bus, train, car, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Indianapolis

    best
    1. Take the bus from Madison to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    12h 2m
    $80–143

  2. Bus

    cheapest
    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    13h 5m
    $77–119

  3. Bus, train via Milwaukee

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 45m
    $188–333

  4. Drive  438.8 mi

    1. Drive from Madison to Jeffersonvillecar car 438.8 mi
    7h 32m
    $81–116

  5. Fly Dane County Regional Airport-Truax Field to Louisville International Airport

    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    7h 37m
    $99–608

  6. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 9m
    $149–274

  7. Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Jeffersonvillecar car
    6h 44m
    $77–339

  8. Bus to Chicago O'Hare International Airport, fly to Covington, drive

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    3. Drive from Covington (CVG) to Jeffersonvillecar car
    7h
    $191–825

  9. Bus to General Mitchell International Airport, fly to Louisville International Airport

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    8h 18m
    $143–838

  10. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    7h 54m
    $96–526

  11. Bus to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    9h
    $130–766

Madison to Jeffersonville by bus and foot

Calendar14Weekly Services
Duration12h 2mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madison to Jeffersonville.ExpandLaunch map view
  • Distance: 472.7 mi
  • Duration: 12h 2m

What companies run services between Madison, WI, USA and Jeffersonville, IN, USA?

You can take a bus from Madison to Court @ Spring via Chicago Bus Station, Indianapolis Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 12h 2m. Alternatively, United Airlines, American Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF) hourly.

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