Rome2Rio

How to get fromMadison to Jeffersonvilleby plane, bus (Amtrak), bus, train, car, or bus (Flixbus)

Find Transport to Jeffersonville

See all options

There are 10 ways to get from Madison to Jeffersonville by plane, bus (Amtrak), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Dane County Regional Airport-Truax Field to Louisville International Airport

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    7h 36m
    $104–608

  2. Bus via Chicago

    cheapest
    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    13h 20m
    $77–119

  3. Bus, train via Milwaukee

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 15m
    $123–261

  4. Drive 438.9 mi

    1. Drive from Madison to Jeffersonvillecar car 438.9 mi
    7h 31m
    $81–116

  5. Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Jeffersonvillecar car
    6h 51m
    $137–719

  6. Bus to General Mitchell International Airport, fly to Louisville International Airport

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    8h 18m
    $116–678

  7. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    7h 50m
    $91–466

  8. Bus to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    8h 59m
    $110–616

  9. Bus

    1. Take the bus from Madison to Cincinnatibus bus FlixBus 2514
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus Cleveland
    13h 50m
    $81–166

  10. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 39m
    $109–234

Madison to Jeffersonville by bus and foot

Calendar14Weekly Services
Duration13h 20mAverage Duration
Ticket$77Cheapest Price
See schedules

Questions & Answers

Map of how to get from Madison to Jeffersonville.ExpandLaunch map view
  • Distance: 408.7 mi
  • Duration: 7h 36m

What companies run services between Madison, WI, USA and Jeffersonville, IN, USA?

United Airlines, American Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from 250 N. Lake St - Madison UW Campus to Court @ Meigs via W Jackson Blvd, after S Clinton St, Chicago Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 13h 20m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers