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How to get fromMadison to Jeffersonvilleby bus (Greyhound, Flixbus), bus, train, car, plane, or bus (Greyhound, Amtrak)

Find Transport to Jeffersonville

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There are 10 ways to get from Madison to Jeffersonville by bus (Greyhound, Flixbus), bus, train, car, plane, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    12h 14m
    $73–137

  2. Bus, train via Speedway

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis to El Mercadito Grocery - Clarksville, INbus bus
    14h 22m
    $139–284

  3. Drive  438.9 mi

    1. Drive from Madison to Jeffersonvillecar car 438.9 mi
    7h 31m
    $81–116

  4. Fly Dane County Regional Airport-Truax Field to Louisville International Airport

    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    7h 27m
    $124–758

  5. Bus via Court @ Meigs

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Train Station to Louisville Bus Stationbus bus Greyhound US0100
    13h 4m
    $78–122

  6. Bus, train

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the bus from Chicago Train Station to Louisville Bus Stationbus bus
    13h 8m
    $94–156

  7. Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Jeffersonvillecar car
    6h 45m
    $77–349

  8. Bus to General Mitchell International Airport, fly to Louisville International Airport

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    8h 28m
    $133–788

  9. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    7h 48m
    $96–516

  10. Bus to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    8h 59m
    $120–716

Madison to Jeffersonville by bus and foot

Calendar40Weekly Services
Duration12h 14mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madison to Jeffersonville.ExpandLaunch map view
  • Distance: 460.1 mi
  • Duration: 12h 14m

What companies run services between Madison, WI, USA and Jeffersonville, IN, USA?

You can take a bus from 250 N. Lake St - Madison UW Campus to Court @ Spring via W Jackson Blvd, after S Clinton St, Chicago Bus Station, Louisville Bus Station, Chestnut @ 13th, Chestnut @ 8th, and Liberty @ Roy Wilkins in around 12h 14m. Alternatively, Delta, United Airlines, and American Airlines fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF) hourly.

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