There are 4 ways to get from Madison to Mayo Clinic by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Madison to Rochesterbus Jefferson Lines 966
4h 28m$50–75Drive 205.4 mi
cheapest- Drive from Madison to Mayo Cliniccar 205.4 mi
3h 41m$38–55Fly to Rochester
- Fly from Dane County Regional Airport-Truax Field (MSN) to Rochester (RST)plane MSN - RST
6h 28m$68–472Fly to Minneapolis–Saint Paul International Airport, bus
- Fly from Dane County Regional Airport-Truax Field (MSN) to Minneapolis–Saint Paul International Airport (MSP)plane MSN - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 32m$124–554
Madison to Mayo Clinic by bus and foot
Questions & Answers
The cheapest way to get from Madison to Mayo Clinic is to drive which costs $35 - $55 and takes 3h 41m.
The fastest way to get from Madison to Mayo Clinic is to drive which takes 3h 41m and costs $35 - $55.
Yes, there is a direct bus departing from Madison and arriving at Rochester. Services depart once daily, and operate every day. The journey takes approximately 4h 20m.
The distance between Madison and Mayo Clinic is 202 miles. The road distance is 206.6 miles.
The best way to get from Madison to Mayo Clinic without a car is to bus which takes 4h 28m and costs $50 - $75.
The bus from Madison to Rochester takes 4h 20m including transfers and departs once daily.
Madison to Mayo Clinic bus services, operated by Jefferson Lines, depart from Madison station.
The best way to get from Madison to Mayo Clinic is to bus which takes 4h 28m and costs $50 - $75. Alternatively, you can fly, which costs $65 - $480 and takes 6h 28m.
Madison to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Rochester station.
Yes, the driving distance between Madison to Mayo Clinic is 207 miles. It takes approximately 3h 41m to drive from Madison to Mayo Clinic.
What companies run services between Madison, WI, USA and Mayo Clinic, MN, USA?
Jefferson Lines operates a bus from Madison to Rochester once daily. Tickets cost $50–75 and the journey takes 4h 20m. Alternatively, United Airlines, American Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Rochester (RST) every 4 hours.
- Website
- delta.com
Flights from Dane County Regional Airport-Truax Field to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $65–430
Flights from Dane County Regional Airport-Truax Field to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 6h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Dane County Regional Airport-Truax Field to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $70–500
- Website
- aa.com
Flights from Dane County Regional Airport-Truax Field to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $70–450
- Website
- united.com
Flights from Dane County Regional Airport-Truax Field to Rochester via Chicago O'Hare
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $70–450
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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