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How to get fromMadison to Saint Charlesby plane, bus, train, bus (Flixbus, Greyhound), car, or taxi

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There are 9 ways to get from Madison to Saint Charles by plane, bus, train, bus (Flixbus, Greyhound), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Dane County Regional Airport-Truax Field

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Des Moines (DSM)plane plane MSN - DSM
    5h 34m
    $172–817

  2. Drive 304.6 mi

    cheapest
    1. Drive from Madison to Saint Charlescar car 304.6 mi
    5h 40m
    $56–81

  3. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the train from Chicago Union Station to Osceola Amtraktrain train California Zephyr
    11h 45m
    $181–356

  4. Bus

    1. Take the bus from Madison to Saint Paul Union Depotbus bus FlixBus 2548
    2. Take the bus from St. Paul to Osceolabus bus Jefferson Lines 805
    12h 10m
    $182–257

  5. Bus to General Mitchell International Airport, fly

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Des Moines (DSM)plane plane MKE - DSM
    7h 9m
    $184–838

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    5h 57m
    $149–605

  7. Bus to Chicago Midway International Airport, fly

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    7h 16m
    $173–775

  8. Bus, train via Milwaukee

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Osceola Amtraktrain train
    11h 49m
    $194–383

  9. Bus, taxi

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus
    3. Take the taxi from Des Moines to Saint Charlestaxi taxi
    12h 19m
    $151–246

Dane County Regional Airport-Truax Field (MSN) to Des Moines (DSM) flights

Calendar142Weekly Planes
Duration5h 26mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Madison to Saint Charles.ExpandLaunch map view
  • Distance: 276.3 mi
  • Duration: 5h 34m

What companies run services between Madison, WI, USA and Saint Charles, IA, USA?

United Airlines, American Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Madison to Saint Charles via St. Paul and Osceola in around 12h 10m.

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