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How to get fromMadison to Sioux Fallsby plane, bus (Flixbus, Greyhound), car, or bus

Find Transport to Sioux Falls

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There are 6 ways to get from Madison to Sioux Falls by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Dane County Regional Airport-Truax Field

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD)plane plane MSN - FSD
    6h 20m
    $79–454

  2. Drive 410.5 mi

    cheapest
    1. Drive from Madison to Sioux Fallscar car 410.5 mi
    7h 57m
    $75–109

  3. Bus

    1. Take the bus from Madison to Minneapolis Bus Stationbus bus FlixBus 2548
    2. Take the bus from Minneapolis to Sioux Fallsbus bus Jefferson Lines 701 / ...
    13h 23m
    $136–197

  4. Bus to General Mitchell International Airport, fly

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Sioux Falls (FSD)plane plane MKE - FSD
    7h 48m
    $95–513

  5. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Sioux Falls (FSD)plane plane ORD - FSD
    7h 7m
    $81–382

  6. Bus via Bloomington

    1. Take the bus from Madison, WI-Lake St. to Mall of America - IKEA - Bloomingtonbus bus Madison
    2. Take the bus from Minneapolis to Sioux Fallsbus bus Jefferson Lines 701 / ...
    13h 27m
    $127–179

Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD) flights

Calendar113Weekly Planes
Duration5h 19mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Madison to Sioux Falls.ExpandLaunch map view
  • Distance: 385.3 mi
  • Duration: 6h 20m

What companies run services between Madison, WI, USA and Sioux Falls, SD, USA?

Delta, United Airlines, and American Airlines fly from Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD) hourly. Alternatively, you can take a bus from Madison to The Bus Stop via Minneapolis, Sioux Falls, and Maple/Career NE corner in around 13h 23m.

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