Rome2Rio

How to get fromMadison to Sioux Fallsby plane, bus (Flixbus, Greyhound), car, bus, or train

Find Transport to Sioux Falls

See all options

There are 7 ways to get from Madison to Sioux Falls by plane, bus (Flixbus, Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Dane County Regional Airport-Truax Field

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD)plane plane MSN - FSD
    6h 5m
    $59–354

  2. Bus

    1. Take the bus from Madison to Minneapolis Bus Stationbus bus FlixBus 2548
    2. Take the bus from Minneapolis to Sioux Fallsbus bus Jefferson Lines 701 / ...
    13h 23m
    $136–197

  3. Drive  410.5 mi

    1. Drive from Madison to Sioux Fallscar car 410.5 mi
    7h 57m
    $75–109

  4. Bus to General Mitchell International Airport, fly

    1. Take the bus from Madison, WI-Lake St. to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Sioux Falls (FSD)plane plane MKE - FSD
    7h 48m
    $103–514

  5. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Sioux Falls (FSD)plane plane ORD - FSD
    7h 9m
    $71–342

  6. Bus via Bloomington

    1. Take the bus from Madison, WI-Lake St. to Mall of America - IKEA - Bloomingtonbus bus Madison
    2. Take the bus from Minneapolis to Sioux Fallsbus bus Jefferson Lines 701 / ...
    13h 26m
    $127–179

  7. Bus, train

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to St. Paul-Minneapolistrain train
    3. Take the bus from Minneapolis to Sioux Fallsbus bus
    16h 4m
    $270–439

Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD) flights

Calendar107Weekly Planes
Duration5h 5mAverage Duration
Ticket$56Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Madison to Sioux Falls.ExpandLaunch map view
  • Distance: 385.3 mi
  • Duration: 6h 5m

What companies run services between Madison, WI, USA and Sioux Falls, SD, USA?

Delta, American Airlines, and United Airlines fly from Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD) hourly. Alternatively, you can take a bus from Madison to The Bus Stop via Minneapolis, Sioux Falls, and Maple/Career NE corner in around 13h 23m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There