There are 8 ways to get from Madrid City Center to Sicily by plane, train, bus, ferry, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
5h 52m€54–191Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the bus from Barcelona - North Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Naples Metropark Central Parkingbus 18
- Take the train from Napoli Centrale to Palermo Centraletrain Ic
38h 5m€251–550Train, ferry, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Genoaferry
- Take the car ferry from Port of Genoa to Port of Palermocarferry
40h 22m€251–463Fly to Catania–Fontanarossa Airport
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
5h 31m€55–228Fly to Trapani Airport
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
8h 24m€64–247Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
46h 33m€275–468Train, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the car ferry from Port de Barcelona to Port of Genoacarferry
- Take the car ferry from Port of Genoa to Port of Palermocarferry
47h 57m€249–461Bus via Sala Consilina
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the bus from Padua Bus Station to Ponte Filo-barca S.da Statale 19 delle Calabriebus
- Take the bus from Sala Consilina Terminal Bus SS19 to Palermo Piazza Cairolibus
2d 7h
Madrid City Center to Sicily by train, foot, and bus
Questions & Answers
The cheapest way to get from Madrid City Center to Sicily is to fly which costs €55 - €230 and takes 5h 31m.
The fastest way to get from Madrid City Center to Sicily is to fly which takes 5h 31m and costs €55 - €230.
No, there is no direct bus from Madrid City Center to Sicily. However, there are services departing from Madrid and arriving at Piazza Boiardo via Milano, Autostazione Lampugnano and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 46h 33m.
The distance between Madrid City Center and Sicily is 1507 km.
The best way to get from Madrid City Center to Sicily without a car is to train and bus which takes 38h 5m and costs €250 - €550.
It takes approximately 5h 52m to get from Madrid City Center to Sicily, including transfers.
Madrid City Center to Sicily bus services, operated by FlixBus, depart from Madrid station.
The best way to get from Madrid City Center to Sicily is to fly which takes 5h 52m and costs €50 - €200. Alternatively, you can bus, which costs €270 - €470 and takes 46h 33m.
Madrid City Center to Sicily bus services, operated by FlixBus, arrive at Milan station.
There are 6404+ hotels available in Sicily.
What companies run services between Madrid City Center, Spain and Sicily, Italy?
Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Madrid to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 46h 33m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday to Thursday
- Estimated price
- €50–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €50–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €70–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €65–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 45m
- When
- Thursday, Tuesday, and Sunday
- Estimated price
- €60–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 55m
- When
- Monday to Friday
- Estimated price
- €65–250
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 22m
- When
- Wednesday, Friday, Monday, and Tuesday
- Estimated price
- €45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €60–130
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 22m
- When
- Wednesday, Friday, Monday, and Tuesday
- Estimated price
- €45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €60–130
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Napoli Centrale to Palermo Centrale
- Ave. Duration
- 9h 19m
- Frequency
- Twice daily
- Estimated price
- €70–150
- Website
- https://www.trenitalia.com/en.html
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Barcelona - North Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 12h 50m
- Frequency
- Twice daily
- Estimated price
- €75–140
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Genoa - Via Fanti d'Italia Bus Stop to Naples Metropark Central Parking
- Ave. Duration
- 8h 50m
- Frequency
- 4 times a week
- Estimated price
- €45–90
- Website
- https://www.itabus.it/en/home
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–240
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €130–230
- Website
- https://www.flixbus.co.uk
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +390981 500331
- [email protected]
- Website
- saj.it
Bus from Padua Bus Station to Ponte Filo-barca S.da Statale 19 delle Calabrie
- Ave. Duration
- 9h 45m
- Frequency
- Twice a week
- Estimated price
- €65–130
- Schedules at
- saj.it
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Sala Consilina Terminal Bus SS19 to Palermo Piazza Cairoli
- Ave. Duration
- 15h 59m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +39 010 209 4591
- [email protected]
- Website
- gnv.it
Ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 13h 5m
- Frequency
- 3 times a week
- Estimated price
- €85–130
- Website
- https://www.gnv.it/en
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- https://www.gnv.it/en
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €85–130
- Website
- https://www.gnv.it/en
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Train travel in Spain: A guide to Renfe
Read the travel guide
What are the different types of Renfe trains in Spain?
Read the travel guide







































