There are 7 ways to get from Madrid to Palermo by plane, train (Renfe, Ouigo, Trenitalia), train, bus, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
6h 1m€54–228Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
31h 3m€330–635Train, bus, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the carferry from Port of Genoa to Port of Palermocarferry
38h 17m€268–410Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
47h 15m€281–431Fly to Trapani Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
9h 34m€107–493Fly to Catania–Fontanarossa Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
8h 44m€62–240Bus via Nice Airport (NCE)
- Take the bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1bus
- Take the bus from Nice Airport to Florencebus
- Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus
2d 2h€328–509
Madrid to Palermo by train
Comparing Your Travel Options
The cheapest way to get from Madrid to Palermo is to fly and bus which costs €100 - €500 and takes 9h 34m.
The fastest way to get from Madrid to Palermo is to fly which takes 6h 1m and costs €50 - €230.
No, there is no direct bus from Madrid to Palermo. However, there are services departing from Neptuno and arriving at Palermo via Madrid and Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 47h 15m.
No, there is no direct train from Madrid to Palermo. However, there are services departing from Sol and arriving at Palermo Centrale via Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 31h 3m.
The distance between Madrid and Palermo is 1507 km.
The best way to get from Madrid to Palermo without a car is to train which takes 31h 3m and costs €330 - €650.
It takes approximately 6h 1m to get from Madrid to Palermo, including transfers.
Madrid to Palermo bus services, operated by FlixBus, depart from Madrid station.
Madrid to Palermo train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Palermo is to fly which takes 6h 1m and costs €50 - €230. Alternatively, you can train, which costs €330 - €650 and takes 31h 3m, you could also bus, which costs €280 - €440 and takes 47h 15m.
What companies run services between Madrid, Spain and Palermo, Italy?
Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) once daily. Alternatively, you can take a train from Sol to Palermo Centrale via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Roma Termini in around 31h 3m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Sunday, Saturday, Monday, Thursday, and Friday
- Estimated price
- €50–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 52m
- When
- Tuesday, Monday, and Friday
- Estimated price
- €65–320
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 6h 29m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Turin
- Ave. Duration
- 6h 25m
- When
- Monday, Thursday, Sunday, and Saturday
- Estimated price
- €65–330
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Sevilla
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- €70–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 40m
- When
- Thursday
- Estimated price
- €45–150
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 30m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €70–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday
- Estimated price
- €55–140
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 30m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €70–250
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €85–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Renfe Viajeros
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 5h 35m
- Frequency
- 5 times a day
- Estimated price
- €28–50
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1
- Ave. Duration
- 20h 45m
- Frequency
- Twice daily
- Estimated price
- €100–180
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 6h 25m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €18–27
- Website
- Flixbus
Bus from Nice Airport to Florence
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €35–55
- Website
- Flixbus
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodi
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- 800 21 10 20
- [email protected]
- Website
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairoli
- Ave. Duration
- 19h 40m
- Frequency
- Twice a week
- Estimated price
- €190–270
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Madrid to Palermo bus services, operated by FlixBus, arrive at Milan station.
Madrid to Palermo train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Book your Madrid to Palermo train tickets online with Omio.
There are 6129+ hotels available in Palermo.














































