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How to get fromMadrid to Palermoby plane, train, bus, or car ferry

Find Transport to Palermo

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There are 7 ways to get from Madrid to Palermo by plane, train, bus, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane plane MAD - PMO
    5h 52m
    €54–229

  2. Train, bus

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Savonabus bus 404
    3. Take the train from Savona to Genova P.Za Principetrain train Ic
    4. Take the train from Genova P.Za Principe to Roma Terminitrain train Fb / ...
    5. Take the train from Roma Termini to Palermo Centraletrain train Ic
    34h 25m
    €311–553

  3. Train, car ferry

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the train from Marseille St Charles to Nice Villetrain train Tgv
    3. Take the train from Ventimiglia to Genova P.Za Principetrain train Ic
    4. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    38h 11m
    €304–481

  4. Bus

    1. Take the bus from Madrid to Milanbus bus FlixBus N1138
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    47h 15m
    €261–411

  5. Fly to Trapani Airport, bus

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane plane MAD - TPS
    2. Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus bus
    9h 19m
    €107–494

  6. Train, car ferry via Barcelona

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the carferry from Port de Barcelona to Port of Genoacarferry car ferry
    3. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    47h 3m
    €233–433

  7. Bus via Nice Airport (NCE)

    1. Take the bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the bus from Nice - Airport Bus Station Terminal 1 to Genoa - Via Fanti d'Italia Bus Stopbus bus
    3. Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Florence - Villa Costanzabus bus 18
    4. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    2d 3h
    €313–487

Madrid to Palermo by train and bus

Calendar14Weekly Services
Duration34h 25mAverage Duration
Ticket€311Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madrid to Palermo.ExpandLaunch map view
  • Distance: 1,506.5 km
  • Duration: 5h 52m

What companies run services between Madrid, Spain and Palermo, Italy?

Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Neptuno to Palermo via Estación Sur, Madrid, and Milano, Autostazione Lampugnano in around 47h 15m.

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