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How to get fromMadrid to Palermoby plane, train (Renfe, Ouigo, Trenitalia), train, car ferry, or bus

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There are 8 ways to get from Madrid to Palermo by plane, train (Renfe, Ouigo, Trenitalia), train, car ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane plane MAD - PMO
    5h 54m
    €54–239

  2. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Roma Terminitrain train
    5. Take the train from Roma Termini to Palermo Centraletrain train Ic
    30h 55m
    €330–615

  3. Train, car ferry

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Villetrain train
    3. Take the train from Ventimiglia to Genova P.Za Principetrain train Ic
    4. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    37h 21m
    €318–475

  4. Bus

    1. Take the bus from Madrid to Milanbus bus FlixBus N1138
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    47h 15m
    €281–431

  5. Fly to Trapani Airport, bus

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane plane MAD - TPS
    2. Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus bus
    9h 34m
    €107–494

  6. Fly to Catania–Fontanarossa Airport, bus

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane plane MAD - CTA
    2. Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus bus
    8h 44m
    €62–231

  7. Train, car ferry via Barcelona

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the carferry from Port de Barcelona to Port of Genoacarferry car ferry
    3. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    45h 49m
    €223–413

  8. Bus via Nice Airport (NCE)

    1. Take the bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1bus bus
    2. Take the bus from Nice Airport to Florencebus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    2d 2h
    €338–534

Madrid to Palermo by train

Calendar14Weekly Trains
Duration30h 55mAverage Duration
Ticket€330Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madrid to Palermo.ExpandLaunch map view
  • Distance: 1,506.5 km
  • Duration: 5h 54m

What companies run services between Madrid, Spain and Palermo, Italy?

Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) once daily. Alternatively, you can take a train from Sol to Palermo Centrale via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Roma Termini in around 30h 55m.

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