There are 12 ways to get from Madrid to Assisi by plane, train, bus, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Fiumicino International Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Fiumicino International Airport (FCO)plane MAD - FCO
- Take the train from Roma Termini to Assisitrain
9h 6m€52–172Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Perpignantrain Tgv
- Take the bus from Perpignan to Florencebus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
22h 19m€165–384Train, ferry, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the bus from CIVITAVECCHIA | Deposito # f277 to FIUMICINO | Aeroportobus
- Take the bus from Fiumicino Aeroporto T3 to Assisi - Piazza San Pietrobus
32h 49m€162–329Drive 1,808.9 km
- Drive from Madrid to Assisicar 1,808.9 km
18h 5m€286–413Fly to Florence Peretola Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane MAD - FLR
- Take the train from Firenze S.M.N. to Assisitrain
9h 35m€82–197Fly to Raffaello Sanzio Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Raffaello Sanzio Airport (AOI)plane MAD - AOI
- Take the train from Jesi to Folignotrain
8h 56m€84–262Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane MAD - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
9h 56m€89–232Fly to Pisa International Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane MAD - PSA
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
10h 37m€94–248Fly to Venice Marco Polo Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Venice Marco Polo Airport (VCE)plane MAD - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
11h 58m€81–257Bus via Genoa
- Take the bus from Madrid to Genoabus
- Take the bus from Genoa to Florence Villa Constanza Bus Stationbus 510 / ...
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
28h 15m€156–263Train, bus via Milan
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Perpignantrain Tgv
- Take the bus from Perpignan - Bus Station to Milano, Autostazione Lampugnanobus
- Take the train from Milano Lambrate to Assisitrain Ic
29h 12m€184–475Bus
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the bus from Padua to Perugiabus N433 / ...
38h 55m€164–216
Madrid to Assisi by train and bus
Questions & Answers
The cheapest way to get from Madrid to Assisi is to fly and train which costs €50 - €180 and takes 9h 6m.
The fastest way to get from Madrid to Assisi is to fly and train which takes 8h 56m and costs €80 - €270.
No, there is no direct bus from Madrid to Assisi. However, there are services departing from Madrid and arriving at Assisi via Genoa and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 28h 15m.
The distance between Madrid and Assisi is 1545 km. The road distance is 1808.9 km.
The best way to get from Madrid to Assisi without a car is to train and bus which takes 22h 19m and costs €160 - €390.
It takes approximately 9h 6m to get from Madrid to Assisi, including transfers.
Madrid to Assisi bus services, operated by FlixBus, depart from Madrid station.
Madrid to Assisi bus services, operated by FlixBus, arrive at Genoa station.
Yes, the driving distance between Madrid to Assisi is 1809 km. It takes approximately 18h 5m to drive from Madrid to Assisi.
Book your Madrid to Assisi bus tickets online with Omio and FlixBus.
What companies run services between Madrid, Spain and Assisi, Italy?
You can take a bus from Madrid to Assisi via Genoa and Florence Villa Constanza Bus Station in around 28h 15m.
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–110
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- €60–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €60–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €65–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Thursday
- Estimated price
- €45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Venice Marco Polo Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- €50–150
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–110
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- €60–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €60–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €65–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Thursday
- Estimated price
- €45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Venice Marco Polo Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- €50–150
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–120
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport via Palma Mallorca
- Ave. Duration
- 4h 10m
- When
- Wednesday
- Estimated price
- €45–120
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €55–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport via Ibiza
- Ave. Duration
- 3h 55m
- When
- Monday to Friday
- Estimated price
- €55–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Venice Marco Polo Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- €40–150
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- €40–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Venice Marco Polo Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €60–150
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €40–140
- Website
- volotea.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €40–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Raffaello Sanzio Airport
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €60–200
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €28–120
Flights from Adolfo Suárez Madrid–Barajas Airport to Venice Marco Polo Airport
- Ave. Duration
- 2h 35m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €29–110
- Website
- lufthansa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Raffaello Sanzio Airport via Munich
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €140–460
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 7m
- Frequency
- Every 2 hours
- Estimated price
- €20–35
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 2 hours
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Jesi to Foligno
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 2 hours
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–16
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 2 hours
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 2 hours
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 4m
- Frequency
- Twice daily
- Estimated price
- €17–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €18–40
- Website
- https://www.trenitalia.com/en.html
Train from Jesi to Foligno
- Ave. Duration
- 1h 25m
- Frequency
- 5 times a day
- Estimated price
- €10–23
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €18–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €18–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €18–40
- Website
- https://www.trenitalia.com/en.html
Train from Milano Lambrate to Assisi
- Ave. Duration
- 5h 49m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Perpignan
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a day
- Estimated price
- €23–35
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Perpignan
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a day
- Estimated price
- €23–35
- Website
- https://www.renfe.com/es/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Barcelona-Sants to Perpignan
- Ave. Duration
- 1h 26m
- Frequency
- 5 times a day
- Estimated price
- €35–65
- Website
- https://www.sncf-connect.com/en-en
Train from Barcelona-Sants to Perpignan
- Ave. Duration
- 1h 26m
- Frequency
- 5 times a day
- Estimated price
- €35–65
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Jesi to Foligno
- Ave. Duration
- 1h 14m
- Frequency
- 3 times a day
- Estimated price
- €15–30
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €35–70
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Perpignan to Florence
- Ave. Duration
- 11h 56m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €14–25
- Website
- https://www.flixbus.co.uk
Bus from Madrid to Genoa
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €120–210
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €18–35
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €14–25
- Website
- https://www.flixbus.co.uk
Bus from Padua to Perugia
- Ave. Duration
- 8h 15m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- https://www.flixbus.co.uk
- Phone
- 800 174 471
- Website
- servizi.cotralspa.it
Bus from CIVITAVECCHIA | Deposito # f277 to FIUMICINO | Aeroporto
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- €3–5
- Schedules at
- servizi.cotralspa.it
- Phone
- +39 075 5009641
- [email protected]
- Website
- sulga.it
Bus from Fiumicino Aeroporto T3 to Assisi - Piazza San Pietro
- Ave. Duration
- 4h 15m
- Frequency
- 6 times a week
- Estimated price
- €23–27
- Schedules at
- sulga.it
- 2nd Class
- €23–27
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- €20–35
- Website
- https://www.blablacar.co.uk/bus
Bus from Perpignan - Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 12h 35m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Perpignan - Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 10h 55m
- Frequency
- Once daily
- Estimated price
- €50–100
- Website
- https://www.itabus.it/en/home
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39.081.496.444
- [email protected]
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €75–130
- Website
- https://www.grimaldi-lines.com/en/
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