There are 7 ways to get from Madrid to Brindisi by plane, train (Renfe, Ouigo, Trenitalia), bus, car, train (Renfe, Ouigo, TGV, Trenitalia), train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brindisi Airport (BDS)plane MAD - BDS
5h 5m€61–221Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Brindisi Stazione Centraletrain Fr
24h 9m€311–576Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milan Lampugnano to Brindisi Istituto Professionale Falconebus Itabus
38h 40m€200–353Drive 2,426.5 km
- Drive from Madrid to Brindisicar 2,426.5 km
24h 11m€397–574Train via Saint-Marcel-lès-Valence
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Valence Tgv Rhone-Alpes Sudtrain Tgv
- Take the train from Valence Tgv Rhone-Alpes Sud to Chambery Challes Les Eauxtrain Ter
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Brindisi Stazione Centraletrain Fr
24h 40m€311–691Train, bus, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Turinbus 404
- Take the nighttrain from Torino Lingotto to Brindisi Stazione Centralenighttrain Ini
30h 2m€284–441Bus via Padova
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the bus from Padua Via Fra' Paolo Sarpi to Taranto Via per San Giorgiobus
- Take the bus from Taranto - Parco Cimino to Brindisi Aeroportobus 001
45h€182–257
Madrid to Brindisi by train
Comparing Your Travel Options
The cheapest way to get from Madrid to Brindisi is to fly which costs €60 - €230 and takes 5h 5m.
The fastest way to get from Madrid to Brindisi is to fly which takes 5h 5m and costs €60 - €230.
No, there is no direct bus from Madrid to Brindisi. However, there are services departing from Madrid and arriving at Brindisi Istituto Professionale Falcone via Milan Lampugnano. The journey, including transfers, takes approximately 38h 40m.
No, there is no direct train from Madrid to Brindisi. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Brindisi Stazione Centrale via Barcelona-Sants, Lyon Part Dieu and Torino Porta Susa. The journey, including transfers, takes approximately 24h 9m.
The distance between Madrid and Brindisi is 1824 km. The road distance is 2426.5 km.
The best way to get from Madrid to Brindisi without a car is to train which takes 24h 9m and costs €310 - €600.
It takes approximately 5h 5m to get from Madrid to Brindisi, including transfers.
Madrid to Brindisi bus services, operated by FlixBus, depart from Madrid station.
Madrid to Brindisi train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Brindisi is to fly which takes 5h 5m and costs €60 - €230. Alternatively, you can train, which costs €310 - €600 and takes 24h 9m, you could also bus, which costs €200 - €360 and takes 38h 40m.
What companies run services between Madrid, Spain and Brindisi, Italy?
Ryanair and ITA Airways fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brindisi Airport (BDS) once daily. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Brindisi Stazione Centrale via Barcelona-Sants, Lyon Part Dieu, and Torino Porta Susa in around 24h 9m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Brindisi Airport
- Ave. Duration
- 2h 50m
- When
- Monday
- Estimated price
- €60–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Brindisi Airport via Rome
- Ave. Duration
- 4h 30m
- When
- Friday
- Estimated price
- €60–250
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Brindisi Airport via Rome
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €100–220
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €85–150
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €85–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- €65–100
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Renfe Viajeros
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 34m
- Frequency
- Twice daily
- Estimated price
- €23–35
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Brindisi Stazione Centrale
- Ave. Duration
- 9h 4m
- Frequency
- Twice daily
- Estimated price
- €150–260
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Brindisi Stazione Centrale
- Ave. Duration
- 9h 4m
- Frequency
- Twice daily
- Estimated price
- €150–260
- Website
- Trenitalia Frecce
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Barcelona-Sants to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 35m
- Frequency
- 3 times a day
- Estimated price
- €35–60
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Valence Tgv Rhone-Alpes Sud to Chambery Challes Les Eaux
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- €27–50
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Valence Tgv Rhone-Alpes Sud to Chambery Challes Les Eaux
- Ave. Duration
- 1h 54m
- Frequency
- Every 2 hours
- Estimated price
- €40–55
- Website
- Zou! Lignes Express Régionales
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Torino Lingotto to Brindisi Stazione Centrale
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Trenitalia ICN
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
Bus from Milan Lampugnano to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 14h 10m
- Frequency
- Twice daily
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Marseille, Gare de Marseille-Saint-Charles to Turin
- Ave. Duration
- 6h 35m
- Frequency
- Once daily
- Estimated price
- €40–65
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Milan Lampugnano to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 14h 35m
- Frequency
- Twice daily
- Estimated price
- €55–100
- Website
- Itabus S.p.A.
Bus from Padua Via Fra' Paolo Sarpi to Taranto Via per San Giorgio
- Ave. Duration
- 14h 5m
- Frequency
- 3 times a week
- Estimated price
- €50–95
- Website
- Itabus S.p.A.
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39 080 5790211
- [email protected]
- Website
- bari.airports.aeroportidipuglia.it
Bus from Taranto - Parco Cimino to Brindisi Aeroporto
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- €6–11
- Schedules at
- ctptaranto.it
- Book at
- bari.airports.aeroportidipuglia.it
- 2nd Class
- €8–11
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Madrid to Brindisi bus services, operated by FlixBus, arrive at Milan station.
Madrid to Brindisi train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between Madrid to Brindisi is 2426 km. It takes approximately 24h 11m to drive from Madrid to Brindisi.
Book your Madrid to Brindisi train tickets online with Omio.
Book your Madrid to Brindisi bus tickets online with Omio and FlixBus.
There are 936+ hotels available in Brindisi.






































