There are 10 ways to get from Madrid to Caltanissetta by plane, bus, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport, bus
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
7h 25m€59–222Train, bus, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the nighttrain from Genova P.Za Principe to Villa S.Giovanninighttrain Ini
- Take the bus from Villa San Giovanni to Caltanissettabus
37h 8m€291–465Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Genevetrain Ter
- Take the train from Genève to Zürich HBtrain Ic1 / ...
- Take the bus from ZÜRICH, Carparkplatz am Sihlquai to Caltanissettabus
38h 57m€464–766Fly Adolfo Suárez Madrid–Barajas Airport to Palermo Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
- Take the bus from Palermo to Caltanissettabus
8h 42m€65–241Fly Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Vincenzo Magliocco Airport (CIY)plane MAD - CIY
- Take the train from Comiso to Caltanissetta C.Letrain
10h 5m€271–1,242Train to Valencia Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Madrid Chamartín to Valencia Joaquin Sorollatrain
- Fly from Valencia Airport (VLC) to Catania–Fontanarossa Airport (CTA)plane VLC - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
9h 21m€93–324Fly Adolfo Suárez Madrid–Barajas Airport to Trapani Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
- Take the bus from Palermo to Caltanissettabus
12h 13m€118–506Train, bus via Rome
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Gironatrain Avn / ...
- Take the bus from Girona, Estació d'Autobusos to Bresciabus
- Take the train from Brescia to Roma Terminitrain
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Caltanissetta C.Letrain Re
40h 38m€313–640Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Caltanissettabus N528
47h€275–413Bus via Marseille
- Take the bus from Estación Sur de Autobuses to Marseille - Saint-Charles Bus Stationbus
- Take the bus from Marseille - Saint-Charles Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
47h 12m€197–343
Madrid to Caltanissetta by train, bus, and night train
Comparing Your Travel Options
The cheapest way to get from Madrid to Caltanissetta is to fly and bus which costs €55 - €230 and takes 7h 25m.
The fastest way to get from Madrid to Caltanissetta is to fly and bus which takes 7h 25m and costs €55 - €230.
No, there is no direct bus from Madrid to Caltanissetta. However, there are services departing from Madrid and arriving at Caltanissetta via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 47h.
The distance between Madrid and Caltanissetta is 1762 km.
The best way to get from Madrid to Caltanissetta without a car is to train and bus and night train which takes 37h 8m and costs €290 - €470.
It takes approximately 7h 25m to get from Madrid to Caltanissetta, including transfers.
Madrid to Caltanissetta bus services, operated by FlixBus, depart from Madrid station.
Madrid to Caltanissetta bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Caltanissetta bus tickets online with Omio and FlixBus.
There are 244+ hotels available in Caltanissetta.
What companies run services between Madrid, Spain and Caltanissetta, Italy?
You can take a bus from Madrid to Caltanissetta via Milano, Autostazione Lampugnano in around 47h.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 40m
- When
- Thursday
- Estimated price
- €45–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Sunday, Saturday, Monday, Thursday, and Friday
- Estimated price
- €50–190
Flights from Valencia Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–200
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 52m
- When
- Tuesday, Monday, and Friday
- Estimated price
- €65–320
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 6h 29m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Turin
- Ave. Duration
- 6h 25m
- When
- Monday, Thursday, Sunday, and Saturday
- Estimated price
- €65–330
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Sevilla
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- €70–260
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday
- Estimated price
- €55–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 30m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €70–250
Flights from Valencia Airport to Catania–Fontanarossa Airport via Barcelona
- Ave. Duration
- 5h 40m
- When
- Tuesday to Thursday
- Estimated price
- €40–180
- Website
- aeroitalia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 40m
- When
- Wednesday, Sunday, and Tuesday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 5h 30m
- When
- Saturday and Sunday
- Estimated price
- €90–350
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 30m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €70–250
Flights from Valencia Airport to Catania–Fontanarossa Airport via Barcelona
- Ave. Duration
- 5h 40m
- When
- Tuesday to Thursday
- Estimated price
- €40–180
- Website
- transavia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Paris Orly
- Ave. Duration
- 7h 52m
- When
- Saturday
- Estimated price
- €120–550
- Website
- flyulendo.com
Flights from Valencia Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €50–170
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h 4m
- Frequency
- 3 times a day
- Estimated price
- €50–75
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Girona
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- Renfe Viajeros
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Genova P.Za Principe to Villa S.Giovanni
- Ave. Duration
- 15h 18m
- Frequency
- Once daily
- Estimated price
- €100–180
- Website
- Trenitalia ICN
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €85–150
- Website
- Renfe AVE
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h 4m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €85–150
- Website
- Renfe AVE
Train from Barcelona-Sants to Girona
- Ave. Duration
- 26 min
- Frequency
- 4 times a day
- Estimated price
- €13–23
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €35–65
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Ouigo
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h 1m
- Frequency
- 4 times a day
- Estimated price
- €30–55
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Ouigo
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Every 3 hours
- Estimated price
- €28–50
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €30–50
- Website
- TGV inOui
Train from Barcelona-Sants to Girona
- Ave. Duration
- 41 min
- Frequency
- Twice daily
- Estimated price
- €18–28
- Website
- TGV inOui
Train from Genève to Zürich HB
- Ave. Duration
- 2h 53m
- Frequency
- Hourly
- Estimated price
- €100–160
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Comiso to Caltanissetta C.Le
- Ave. Duration
- 2h 6m
- Frequency
- Twice daily
- Estimated price
- €17–25
- Website
- Trenitalia
Train from Termini Imerese to Caltanissetta C.Le
- Ave. Duration
- 1h 22m
- Frequency
- Once daily
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Brescia to Roma Termini
- Ave. Duration
- 4h 11m
- Frequency
- Every 4 hours
- Estimated price
- €60–110
- Website
- Italo Treno
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Brescia to Roma Termini
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Palermo to Caltanissetta
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €9–13
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Palermo to Caltanissetta
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €9–13
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 5h 35m
- Frequency
- Every 3 hours
- Estimated price
- €28–50
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Marseille - Saint-Charles Bus Station
- Ave. Duration
- 15h 20m
- Frequency
- 5 times a day
- Estimated price
- €80–140
- Website
- BlaBlaCar Bus
Bus from Marseille - Saint-Charles Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 7h 35m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 6h 25m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Villa San Giovanni to Caltanissetta
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- €19–29
- Website
- Flixbus
Bus from Girona, Estació d'Autobusos to Brescia
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €95–150
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Caltanissetta
- Ave. Duration
- 22h 55m
- Frequency
- Once daily
- Estimated price
- €130–200
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from ZÜRICH, Carparkplatz am Sihlquai to Caltanissetta
- Ave. Duration
- 22h 14m
- Frequency
- Once a week
- Estimated price
- €210–290
- Website
- Onebus
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodi
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 20h 10m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- Itabus S.p.A.
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