There are 8 ways to get from Madrid to Caltanissetta by plane, bus, train, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Catania–Fontanarossa Airport, bus
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
7h 20m€64–222Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Montpellier Saint-Rochtrain
- Take the train from Montpellier Saint-Roch to Mulhouse Villetrain Tgv
- Take the bus from Basel to Caltanissettabus
38h 5m€438–782Train, car ferry, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the carferry from Port de Barcelona to Port of Genoacarferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
- Take the bus from Palermo to Caltanissettabus
2d 2h€253–453Fly to Palermo Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
9h 3m€71–250Fly to Vincenzo Magliocco Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Vincenzo Magliocco Airport (CIY)plane MAD - CIY
- Take the train from Comiso to Caltanissetta C.Letrain
10h 20m€271–1,242Train, bus via Paris
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain
- Take the train from Barcelona-Sants to Paris Gare De Lyontrain
- Take the train from Paris Gare De Lyon to Zuerich Hbtrain
- Take the bus from ZÜRICH, Carparkplatz am Sihlquai to Catenanuovabus
- Take the train from Catenanuova-Centurip to Caltanissetta C.Letrain
39h 48m€580–926Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Caltanissettabus N528
47h€258–396Bus, train
- Take the bus from Estación Sur de Autobuses to Lyon - Gerland Bus Stationbus
- Take the bus from Lione to Turin Stura Bus Stationbus
- Take the bus from Turin Stura Bus Station to Catania Via D'Amico Bus Stationbus
- Take the train from Catania Centrale to Caltanissetta C.Letrain Re
2d 2h€195–335
Madrid to Caltanissetta by bus
Comparing Your Travel Options
The cheapest way to get from Madrid to Caltanissetta is to fly and bus which costs €60 - €230 and takes 7h 20m.
The fastest way to get from Madrid to Caltanissetta is to fly and bus which takes 7h 20m and costs €60 - €230.
No, there is no direct bus from Madrid to Caltanissetta. However, there are services departing from Madrid and arriving at Caltanissetta via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 47h.
The distance between Madrid and Caltanissetta is 1762 km.
The best way to get from Madrid to Caltanissetta without a car is to train and bus which takes 38h 5m and costs €430 - €800.
It takes approximately 7h 20m to get from Madrid to Caltanissetta, including transfers.
Madrid to Caltanissetta bus services, operated by FlixBus, depart from Madrid station.
Madrid to Caltanissetta bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Caltanissetta bus tickets online with Omio and FlixBus.
There are 245+ hotels available in Caltanissetta.
What companies run services between Madrid, Spain and Caltanissetta, Italy?
You can take a bus from Madrid to Caltanissetta via Milano, Autostazione Lampugnano in around 47h.
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- €65–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Barcelona
- Ave. Duration
- 5h 31m
- When
- Tuesday, Wednesday, Thursday, Saturday, Sunday, and Monday
- Estimated price
- €40–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Saturday
- Estimated price
- €110–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 56m
- When
- Monday to Saturday
- Estimated price
- €75–310
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- €65–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Barcelona
- Ave. Duration
- 5h 31m
- When
- Tuesday, Wednesday, Thursday, Saturday, Sunday, and Monday
- Estimated price
- €40–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- €75–310
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday, Friday, Tuesday, and Monday
- Estimated price
- €50–180
- Website
- aeroitalia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €75–350
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 5h 30m
- When
- Saturday and Sunday
- Estimated price
- €85–360
- Website
- transavia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Paris Orly
- Ave. Duration
- 6h 47m
- When
- Saturday
- Estimated price
- €110–550
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–100
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–100
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €50–80
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €50–80
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €50–80
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Montpellier Saint-Roch
- Ave. Duration
- 3h 6m
- Frequency
- 4 times a day
- Estimated price
- €40–65
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Barcelona-Sants to Montpellier Saint-Roch
- Ave. Duration
- 3h 17m
- Frequency
- Twice daily
- Estimated price
- €65–100
- Website
- TGV inOui
Train from Montpellier Saint-Roch to Mulhouse Ville
- Ave. Duration
- 5h 12m
- Frequency
- 5 times a day
- Estimated price
- €130–210
- Website
- TGV inOui
Train from Barcelona-Sants to Paris Gare De Lyon
- Ave. Duration
- 6h 47m
- Frequency
- 4 times a day
- Estimated price
- €210–310
- Website
- TGV inOui
Train from Paris Gare De Lyon to Zuerich Hb
- Ave. Duration
- 4h 4m
- Frequency
- Every 3 hours
- Estimated price
- €120–180
- Website
- TGV inOui
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 2 hours
- Estimated price
- €15–21
- Website
- Trenitalia
Train from Comiso to Caltanissetta C.Le
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €17–25
- Website
- Trenitalia
Train from Catenanuova-Centurip to Caltanissetta C.Le
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Catania Centrale to Caltanissetta C.Le
- Ave. Duration
- 2h 2m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Palermo to Caltanissetta
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €9–13
- Website
- SAIS Transporti
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Basel to Caltanissetta
- Ave. Duration
- 22h 57m
- Frequency
- Once a week
- Estimated price
- €210–300
- Website
- Onebus
Bus from ZÜRICH, Carparkplatz am Sihlquai to Catenanuova
- Ave. Duration
- 20h 28m
- Frequency
- Once a week
- Estimated price
- €190–270
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €130–210
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Caltanissetta
- Ave. Duration
- 22h 55m
- Frequency
- Once daily
- Estimated price
- €120–190
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Lyon - Gerland Bus Station
- Ave. Duration
- 17h 10m
- Frequency
- Every 4 hours
- Estimated price
- €85–140
- Website
- BlaBlaCar Bus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lione to Turin Stura Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- €16–29
- Website
- Itabus S.p.A.
Bus from Turin Stura Bus Station to Catania Via D'Amico Bus Station
- Ave. Duration
- 22h 45m
- Frequency
- Twice daily
- Estimated price
- €80–150
- Website
- Itabus S.p.A.
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €80–120
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in Spain: A guide to Renfe
Read the travel guide




































