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How to get fromMadrid to Mainzby plane, train (Renfe, Ouigo, TGV), bus, car, train, train (Renfe, TGV), or car train

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There are 8 ways to get from Madrid to Mainz by plane, train (Renfe, Ouigo, TGV), bus, car, train, train (Renfe, TGV), or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Frankfurt (FRA)plane plane MAD - FRA
    5h 19m
    €85–262

  2. Train via Barcelona

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Mannheim Hbftrain train Tgv
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    17h 2m
    €259–512

  3. Bus

    1. Take the bus from Estación Sur de Autobuses to Frankfurt - Airport Bus Stationbus bus BlaBlaCar Bus
    30h 2m
    €158–257

  4. Drive  1,734.6 km

    1. Drive from Madrid to Mainzcar car 1,734.6 km
    17h 16m
    €284–410

  5. Fly to Düsseldorf International Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Düsseldorf International Airport (DUS)plane plane MAD - DUS
    2. Take the train from Duesseldorf Hbf to Frankfurt(M) Flughafen Fernbftrain train
    7h 28m
    €98–339

  6. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgvtrain train
    2. Take the train from Avignon Tgv to Mannheim Hbftrain train Tgv
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    17h 9m
    €315–505

  7. Bus via Valladolid

    1. Take the bus from Estación Sur de Autobuses to Valladolidbus bus ALSA - Mad-Cl-Ast / ...
    2. Take the bus from Valladolid to Mainz central train stationbus bus FlixBus N1151
    31h 45m
    €167–266

  8. Drive, car train

    1. Drive from Madrid to Lörrach Hbfcar car
    2. Take the cartrain from Lörrach Hbf to Frankfurtcartrain train
    20h 56m
    €347–475

Madrid to Mainz by train

Calendar7Weekly Trains
Duration17h 2mAverage Duration
Ticket€259Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madrid to Mainz.ExpandLaunch map view
  • Distance: 1,459.6 km
  • Duration: 5h 19m

What companies run services between Madrid, Spain and Mainz, Germany?

Iberia, Lufthansa, and Air Europa fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Frankfurt (FRA) every 3 hours. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Mainz, Hauptbahnhof via Barcelona-Sants, Lyon Part Dieu, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 17h 2m.

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