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How to get fromMadrid to Mayo Clinicby plane, car, or bus

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There are 3 ways to get from Madrid to Mayo Clinic by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Rochester (RST)plane plane MAD - RST
    19h 27m
    $242–942

  2. Fly to Waterloo Municipal Airport, drive

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Waterloo Municipal Airport (ALO)plane plane MAD - ALO
    2. Drive from Waterloo Municipal Airport (ALO) to Mayo Cliniccar car
    21h 39m
    $260–930

  3. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Minneapolis–Saint Paul International Airport (MSP)plane plane MAD - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    17h 36m
    $361–1,252

Adolfo Suárez Madrid–Barajas Airport (MAD) to Rochester (RST) flights

Calendar16Weekly Planes
Duration17h 18mAverage Duration
Ticket$247Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madrid to Mayo Clinic.ExpandLaunch map view
  • Distance: 4,337.6 mi
  • Duration: 19h 27m

What companies run services between Madrid, Spain and Mayo Clinic, MN, USA?

American Airlines, Iberia, and Delta fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Rochester (RST) twice daily.

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