There are 5 ways to get from Madrid to Medellín by bus, train (Renfe), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Estación Sur de Autobuses to Don Benitobus 900 / ...
5h 25m€32–44Train (Renfe)
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Puertollanotrain Avn / ...
- Take the train from Puertollano to Villanueva De La Serenatrain Re / ...
5h 59m€50–86Drive 320.2 km
- Drive from Madrid to Medellíncar 320.2 km
3h 13m€50–72Bus via Mérida
- Take the bus from Estación Sur de Autobuses to Meridabus BlaBlaCar Bus
- Take the bus from Mérida to Medellínbus Mérida / ...
5h 49m€33–51Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Navalmoral De La Matatrain Alv / ...
- Take the bus from Navalmoral de la Mata to Villamesíasbus
- Take the bus from Villamesías to Medellínbus
6h 26m€47–65
Madrid to Medellín by bus
Comparing Your Travel Options
The cheapest way to get from Madrid to Medellín is to bus which costs €30 - €45 and takes 5h 25m.
The fastest way to get from Madrid to Medellín is to drive which takes 3h 13m and costs €45 - €75.
No, there is no direct bus from Madrid to Medellín. However, there are services departing from Estación Sur de Autobuses and arriving at Medellín via Don Benito. The journey, including transfers, takes approximately 5h 25m.
No, there is no direct train from Madrid to Medellín. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Villanueva De La Serena via Puertollano. The journey, including transfers, takes approximately 5h 59m.
The distance between Madrid and Medellín is 324 km. The road distance is 320.2 km.
The best way to get from Madrid to Medellín without a car is to bus which takes 5h 25m and costs €30 - €45.
It takes approximately 5h 25m to get from Madrid to Medellín, including transfers.
Madrid to Medellín bus services, operated by Autocares Grupo Samar, depart from Estación Sur de Autobuses station.
Madrid to Medellín train services, operated by Renfe Viajeros, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Medellín is to bus which takes 5h 25m and costs €30 - €45. Alternatively, you can train, which costs €50 - €90 and takes 5h 59m.
What companies run services between Madrid, Spain and Medellín, Spain?
Autocares Grupo Samar operates a bus from Estación Sur de Autobuses to Don Benito twice daily. Tickets cost €30–45 and the journey takes 4h 15m. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Medellín via Puertollano, Villanueva De La Serena, and Villanueva de la Serena in around 5h 59m.
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Puertollano
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Renfe Viajeros
Train from Puertollano to Villanueva De La Serena
- Ave. Duration
- 2h 14m
- Frequency
- 4 times a day
- Estimated price
- €22–35
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Navalmoral De La Mata
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Renfe Viajeros
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Puertollano
- Ave. Duration
- 1h 9m
- Frequency
- 5 times a day
- Estimated price
- €28–50
- Website
- Renfe AVE
- Phone
- +34 984 689 912
- [email protected]
- Website
- samar.es
Bus from Estación Sur de Autobuses to Don Benito
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Schedules at
- samar.es
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Merida
- Ave. Duration
- 3h 59m
- Frequency
- Once daily
- Estimated price
- €27–45
- Website
- BlaBlaCar Bus
- Phone
- +34 916 52 00 11
- [email protected]
- Website
- grupointerbus.com
Bus from Mérida to Medellín
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- €5–6
- Schedules at
- grupointerbus.com
Bus from Villamesías to Medellín
- Ave. Duration
- 1h 5m
- Frequency
- 5 times a week
- Estimated price
- €5–7
- Schedules at
- grupointerbus.com
- Phone
- +34 91 272 28 32
- [email protected]
- Website
- avanzabus.com
Bus from Navalmoral de la Mata to Villamesías
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- €17–22
- Schedules at
- avanzabus.com
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Train travel in Spain: A guide to Renfe
Read the travel guide
What are the different types of Renfe trains in Spain?
Read the travel guide
Booking & Getting There
Madrid to Medellín bus services, operated by Autocares Grupo Samar, arrive at Don Benito station.
Madrid to Medellín train services, operated by Renfe Viajeros, arrive at Puertollano station.
Yes, the driving distance between Madrid to Medellín is 320 km. It takes approximately 3h 13m to drive from Madrid to Medellín.
There are 47+ hotels available in Medellín.

































