There are 9 ways to get from Madrid to Mendrisio by plane, train, train (Renfe, Ouigo, Trenitalia), bus, car, or train (Renfe, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Milano Malpensa Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milano Malpensa Airport (MXP)plane MAD - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 48mCHF 27–222Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain
16h 26mCHF 203–410Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milan to Comobus FlixBus 1524 / ...
26h 24mCHF 130–209Drive 1,495.5 km
- Drive from Madrid to Mendrisiocar 1,495.5 km
16h 39mCHF 248–359Fly to Milan Linate Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milan Linate Airport (LIN)plane MAD - LIN
- Take the train from Monza to Mendrisiotrain
6h 39mCHF 71–211Fly to Il Caravaggio International Airport, bus, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Il Caravaggio International Airport (BGY)plane MAD - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Mendrisiotrain
7h 9mCHF 69–315Fly to Zurich Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Zurich Airport (ZRH)plane MAD - ZRH
- Take the train from Zürich HB to Luganotrain
7h 28mCHF 135–410Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain
- Take the train from Nice Saint-Augustin to Ventimigliatrain C3
- Take the train from Ventimiglia to Gallaratetrain
21h 16mCHF 235–416Bus, train
- Take the bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1bus
- Take the bus from Nice - Airport Bus Station Terminal 1 to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the train from Genova Piazza Principe to Como S.Giovannitrain
29h 12mCHF 144–248
Madrid to Mendrisio by train
Questions & Answers
The cheapest way to get from Madrid to Mendrisio is to fly and train which costs SFr 26 - SFr 230 and takes 5h 48m.
The fastest way to get from Madrid to Mendrisio is to fly and train which takes 5h 48m and costs SFr 26 - SFr 230.
No, there is no direct bus from Madrid to Mendrisio. However, there are services departing from Madrid and arriving at Mendrisio, Autosilo via Milan, Como - San Rocchetto and Chiasso, Stazione. The journey, including transfers, takes approximately 26h 24m.
No, there is no direct train from Madrid to Mendrisio. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Mendrisio via Barcelona-Sants, Lyon Part Dieu and Milano Centrale. The journey, including transfers, takes approximately 16h 26m.
The distance between Madrid and Mendrisio is 1218 km. The road distance is 1495.5 km.
The best way to get from Madrid to Mendrisio without a car is to train via Barcelona which takes 16h 26m and costs SFr 200 - SFr 410.
It takes approximately 5h 48m to get from Madrid to Mendrisio, including transfers.
Madrid to Mendrisio bus services, operated by FlixBus, depart from Madrid station.
Madrid to Mendrisio train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Mendrisio is to train via Barcelona which takes 16h 26m and costs SFr 200 - SFr 410. Alternatively, you can bus, which costs SFr 130 - SFr 210 and takes 26h 24m.
What companies run services between Madrid, Spain and Mendrisio, Switzerland?
You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Mendrisio via Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 16h 26m. Alternatively, you can take a bus from Madrid to Mendrisio, Autosilo via Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 26h 24m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- CHF 21–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 45–230
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport via Ibiza
- Ave. Duration
- 4h 26m
- When
- Saturday, Monday, Tuesday, Wednesday, and Sunday
- Estimated price
- CHF 45–230
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- Trenord
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- Trenord
Train from Genova Piazza Principe to Como S.Giovanni
- Ave. Duration
- 2h 55m
- Frequency
- Twice a week
- Estimated price
- CHF 11–15
- Website
- Trenord
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- CHF 120–200
- Website
- Flixbus
Bus from Milan to Como
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- CHF 3–6
- Website
- Flixbus
Want to know more about travelling around Switzerland
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More Questions & Answers
Madrid to Mendrisio bus services, operated by FlixBus, arrive at Milan station.
Madrid to Mendrisio train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between Madrid to Mendrisio is 1496 km. It takes approximately 16h 39m to drive from Madrid to Mendrisio.
There are 5760+ hotels available in Mendrisio.









