There are 9 ways to get from Madrid to Mendrisio by plane, train, train (Renfe, Ouigo, Trenitalia), bus, car, or train (Renfe, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Milano Malpensa Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milano Malpensa Airport (MXP)plane MAD - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 48mCHF 26–202Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain
16h 26mCHF 198–411Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milan to Comobus FlixBus 1524 / ...
26h 24mCHF 126–204Drive 1,495.5 km
- Drive from Madrid to Mendrisiocar 1,495.5 km
16h 38mCHF 244–353Fly to Milan Linate Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milan Linate Airport (LIN)plane MAD - LIN
- Take the train from Monza to Mendrisiotrain
6h 39mCHF 71–211Fly to Il Caravaggio International Airport, bus, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Il Caravaggio International Airport (BGY)plane MAD - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Mendrisiotrain
7h 9mCHF 69–305Fly to Zurich Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Zurich Airport (ZRH)plane MAD - ZRH
- Take the train from Zürich HB to Luganotrain
7h 28mCHF 130–410Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain
- Take the train from Nice Saint-Augustin to Ventimigliatrain C3
- Take the train from Ventimiglia to Milano Centraletrain Ic
- Take the train from Milano Centrale to Mendrisiotrain
19h 36mCHF 245–458Bus, train
- Take the bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1bus
- Take the bus from Nice - Airport Bus Station Terminal 1 to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the train from Genova Piazza Principe to Como S.Giovannitrain
29h 12mCHF 148–266
Madrid to Mendrisio by train
Questions & Answers
The cheapest way to get from Madrid to Mendrisio is to fly and train which costs SFr 25 - SFr 210 and takes 5h 48m.
The fastest way to get from Madrid to Mendrisio is to fly and train which takes 5h 48m and costs SFr 25 - SFr 210.
No, there is no direct bus from Madrid to Mendrisio. However, there are services departing from Madrid and arriving at Mendrisio, Autosilo via Milan, Como - San Rocchetto and Chiasso, Stazione. The journey, including transfers, takes approximately 26h 24m.
No, there is no direct train from Madrid to Mendrisio. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Mendrisio via Barcelona-Sants, Lyon Part Dieu and Milano Centrale. The journey, including transfers, takes approximately 16h 26m.
The distance between Madrid and Mendrisio is 1218 km. The road distance is 1495.5 km.
The best way to get from Madrid to Mendrisio without a car is to train via Barcelona which takes 16h 26m and costs SFr 190 - SFr 420.
It takes approximately 5h 48m to get from Madrid to Mendrisio, including transfers.
Madrid to Mendrisio bus services, operated by FlixBus, depart from Madrid station.
Madrid to Mendrisio train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Mendrisio is to train via Barcelona which takes 16h 26m and costs SFr 190 - SFr 420. Alternatively, you can bus, which costs SFr 120 - SFr 210 and takes 26h 24m.
What companies run services between Madrid, Spain and Mendrisio, Switzerland?
You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Mendrisio via Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 16h 26m. Alternatively, you can take a bus from Madrid to Mendrisio, Autosilo via Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 26h 24m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- CHF 22–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 40–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport via Ibiza
- Ave. Duration
- 4h 26m
- When
- Saturday, Monday, Tuesday, Wednesday, and Sunday
- Estimated price
- CHF 40–220
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- CHF 60–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 60–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- CHF 65–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport via Barcelona
- Ave. Duration
- 5h
- When
- Monday and Friday
- Estimated price
- CHF 80–230
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- CHF 60–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 60–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- CHF 65–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport via Barcelona
- Ave. Duration
- 5h
- When
- Monday and Friday
- Estimated price
- CHF 80–230
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- CHF 45–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 60–190
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 21–120
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport via Palma Mallorca
- Ave. Duration
- 4h 22m
- When
- Thursday and Sunday
- Estimated price
- CHF 85–190
- Website
- swiss.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- CHF 75–190
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- Trenord
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- Trenord
Train from Genova Piazza Principe to Como S.Giovanni
- Ave. Duration
- 2h 55m
- Frequency
- Twice a week
- Estimated price
- CHF 11–15
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 55–180
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- Swiss Federal Railways (SBB CFF FFS)
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- CHF 85–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- CHF 55–120
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- 5 times a day
- Estimated price
- CHF 50–90
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- CHF 70–110
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- CHF 75–120
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- CHF 130–210
- Website
- Renfe Viajeros
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- CHF 50–85
- Website
- Trenitalia
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- CHF 30–55
- Website
- Trenitalia
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Marseille-Saint-Charles to Nice-Saint-Augustin
- Ave. Duration
- 2h 32m
- Frequency
- Hourly
- Estimated price
- CHF 50–110
- Website
- Zou! Lignes Express Régionales
Train from Nice Saint-Augustin to Ventimiglia
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 9–19
- Website
- Zou! Lignes Express Régionales
- Phone
- +33 4 13 94 30 50
- Website
- ZOU!
Train from Nice Saint-Augustin to Ventimiglia
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Schedules at
- ZOU!
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- CHF 28–60
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- CHF 120–200
- Website
- Flixbus
Bus from Milan to Como
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- CHF 3–6
- Website
- Flixbus
- [email protected]
- Website
- TERRAVISION
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–23
- Website
- TERRAVISION
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- CHF 110–210
- Website
- BlaBlaCar Bus
Bus from Nice - Airport Bus Station Terminal 1 to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 3h 10m
- Frequency
- Every 4 hours
- Estimated price
- CHF 16–29
- Website
- BlaBlaCar Bus
Want to know more about travelling around Switzerland
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More Questions & Answers
Madrid to Mendrisio bus services, operated by FlixBus, arrive at Milan station.
Madrid to Mendrisio train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between Madrid to Mendrisio is 1496 km. It takes approximately 16h 38m to drive from Madrid to Mendrisio.
There are 5870+ hotels available in Mendrisio.









































