There are 9 ways to get from Madrid to Mendrisio by plane, train, train (Renfe, Ouigo, Trenitalia), bus, car, or train (Renfe, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Milano Malpensa Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milano Malpensa Airport (MXP)plane MAD - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 48mCHF 27–197Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain
16h 46mCHF 199–418Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milan to Comobus FlixBus 1524 / ...
26h 24mCHF 133–220Drive 1,495.5 km
- Drive from Madrid to Mendrisiocar 1,495.5 km
16h 38mCHF 244–352Fly to Milan Linate Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milan Linate Airport (LIN)plane MAD - LIN
- Take the train from Monza to Mendrisiotrain
6h 39mCHF 71–201Fly to Il Caravaggio International Airport, bus, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Il Caravaggio International Airport (BGY)plane MAD - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Mendrisiotrain
7h 9mCHF 65–255Fly to Zurich Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Zurich Airport (ZRH)plane MAD - ZRH
- Take the train from Zürich HB to Luganotrain
7h 28mCHF 140–422Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Villetrain
- Take the train from Ventimiglia to Milano Centraletrain Ic
- Take the train from Milano Centrale to Mendrisiotrain
18h 51mCHF 233–451Bus, train
- Take the bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1bus
- Take the train from Nice Saint-Augustin to Ventimigliatrain C3
- Take the train from Ventimiglia to Milano Centraletrain Ic
- Take the train from Milano Centrale to Mendrisiotrain
28h 8mCHF 178–350
Madrid to Mendrisio by train
Questions & Answers
The cheapest way to get from Madrid to Mendrisio is to fly and train which costs SFr 26 - SFr 200 and takes 5h 48m.
The fastest way to get from Madrid to Mendrisio is to fly and train which takes 5h 48m and costs SFr 26 - SFr 200.
No, there is no direct bus from Madrid to Mendrisio. However, there are services departing from Madrid and arriving at Mendrisio, Autosilo via Milan, Como - San Rocchetto and Chiasso, Stazione. The journey, including transfers, takes approximately 26h 24m.
No, there is no direct train from Madrid to Mendrisio. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Mendrisio via Barcelona-Sants, Lyon Part Dieu and Milano Centrale. The journey, including transfers, takes approximately 16h 46m.
The distance between Madrid and Mendrisio is 1218 km. The road distance is 1495.5 km.
The best way to get from Madrid to Mendrisio without a car is to train via Barcelona which takes 16h 46m and costs SFr 190 - SFr 420.
It takes approximately 5h 48m to get from Madrid to Mendrisio, including transfers.
Madrid to Mendrisio bus services, operated by FlixBus, depart from Madrid station.
Madrid to Mendrisio train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Mendrisio is to train via Barcelona which takes 16h 46m and costs SFr 190 - SFr 420. Alternatively, you can bus, which costs SFr 130 - SFr 220 and takes 26h 24m.
What companies run services between Madrid, Spain and Mendrisio, Switzerland?
You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Mendrisio via Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 16h 46m. Alternatively, you can take a bus from Madrid to Mendrisio, Autosilo via Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 26h 24m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- CHF 25–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 30–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport via Ibiza
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- CHF 30–160
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- CHF 60–110
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 60–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- CHF 65–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport via Barcelona
- Ave. Duration
- 5h
- When
- Monday and Friday
- Estimated price
- CHF 80–230
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- CHF 60–110
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 60–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- CHF 65–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport via Barcelona
- Ave. Duration
- 5h
- When
- Monday and Friday
- Estimated price
- CHF 80–230
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- CHF 60–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 60–180
- Website
- swiss.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- CHF 80–190
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 21–90
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport via Palma Mallorca
- Ave. Duration
- 4h 22m
- When
- Thursday and Sunday
- Estimated price
- CHF 85–180
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- https://www.trenord.it/en/
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 20–65
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 20–60
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 20–60
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 60–190
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 20–60
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 20–60
- Website
- https://www.sbb.ch/en
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 85–160
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- CHF 60–120
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- CHF 50–95
- Website
- https://www.ouigo.com/es/en
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- CHF 70–120
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- CHF 75–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- CHF 130–210
- Website
- https://www.renfe.com/es/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- CHF 50–85
- Website
- https://www.trenitalia.com/en.html
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 4h 26m
- Frequency
- Twice daily
- Estimated price
- CHF 30–55
- Website
- https://www.trenitalia.com/en.html
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 4h 26m
- Frequency
- Twice daily
- Estimated price
- CHF 30–55
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 4 13 94 30 50
- Website
- zou.maregionsud.fr
Train from Marseille-Saint-Charles to Nice-Ville
- Ave. Duration
- 2h 41m
- Frequency
- Hourly
- Estimated price
- CHF 50–110
- Website
- https://zou.maregionsud.fr/en/
Train from Nice Saint-Augustin to Ventimiglia
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- CHF 9–19
- Website
- https://zou.maregionsud.fr/en/
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Marseille-Saint-Charles to Nice-Ville
- Ave. Duration
- 2h 36m
- Frequency
- Every 2 hours
- Estimated price
- CHF 40–70
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 3h 45m
- Frequency
- Hourly
- Estimated price
- CHF 28–60
- Website
- https://www.trenitalia.com/en.html
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 3h 45m
- Frequency
- Hourly
- Estimated price
- CHF 28–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 4 13 94 30 50
- Website
- zou.maregionsud.fr
Train from Nice Saint-Augustin to Ventimiglia
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Schedules at
- zou.maregionsud.fr
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- CHF 120–210
- Website
- https://www.flixbus.co.uk
Bus from Milan to Como
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- CHF 3–6
- Website
- https://www.flixbus.co.uk
- [email protected]
- Website
- terravision.eu
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–23
- Website
- https://www.terravision.eu/
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Estación Sur de Autobuses to Nice - Airport Bus Station Terminal 1
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- CHF 110–210
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Switzerland
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More Questions & Answers
Madrid to Mendrisio bus services, operated by FlixBus, arrive at Milan station.
Madrid to Mendrisio train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between Madrid to Mendrisio is 1496 km. It takes approximately 16h 38m to drive from Madrid to Mendrisio.
There are 5885+ hotels available in Mendrisio.













































