Rome2Rio

How to get fromMadrid to Mendrisioby plane, train, train (Renfe, Ouigo, TGV, Trenitalia), bus, car, or train (Renfe, TGV, Trenitalia)

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There are 9 ways to get from Madrid to Mendrisio by plane, train, train (Renfe, Ouigo, TGV, Trenitalia), bus, car, or train (Renfe, TGV, Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Milano Malpensa Airport, train

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milano Malpensa Airport (MXP)plane plane MAD - MXP
    2. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    5h 48m
    CHF 26–176

  2. Train via Barcelona

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Mendrisiotrain train
    16h 26m
    CHF 183–417

  3. Bus

    1. Take the bus from Madrid to Milanbus bus FlixBus N1138
    2. Take the bus from Milan to Comobus bus FlixBus 1524 / ...
    26h 17m
    CHF 136–205

  4. Drive  1,495.5 km

    1. Drive from Madrid to Mendrisiocar car 1,495.5 km
    16h 39m
    CHF 249–360

  5. Fly to Milan Linate Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milan Linate Airport (LIN)plane plane MAD - LIN
    2. Take the train from Monza to Mendrisiotrain train
    6h 39m
    CHF 71–200

  6. Fly to Il Caravaggio International Airport, bus, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Il Caravaggio International Airport (BGY)plane plane MAD - BGY
    2. Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus bus
    3. Take the train from Milano Centrale to Mendrisiotrain train
    7h 2m
    CHF 67–287

  7. Fly to Zurich Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Zurich Airport (ZRH)plane plane MAD - ZRH
    2. Take the train from Zürich HB to Luganotrain train
    7h 28m
    CHF 120–322

  8. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the train from Marseille St Charles to Nice Villetrain train Tgv
    3. Take the train from Ventimiglia to Milano Centraletrain train Ic
    4. Take the train from Milano Centrale to Mendrisiotrain train
    19h 6m
    CHF 228–359

  9. Bus, train

    1. Take the bus from Estación Sur de Autobuses to Lyon - Gerland Bus Stationbus bus
    2. Take the bus from Lione to Turin Stura Bus Stationbus bus
    3. Take the bus from Torino Auchan to Milan Malpensa Airportbus bus 020
    4. Take the train from Malpensa Aeroporto T2 to Mendrisiotrain train S50
    27h 38m
    CHF 110–207

Madrid to Mendrisio by train

Calendar16Weekly Trains
Duration16h 26mAverage Duration
TicketCHF 183Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madrid to Mendrisio.ExpandLaunch map view
  • Distance: 1,218 km
  • Duration: 5h 48m

What companies run services between Madrid, Spain and Mendrisio, Switzerland?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Mendrisio via Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 16h 26m. Alternatively, you can take a bus from Madrid to Mendrisio, Autosilo via Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 26h 17m.

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Want to know more about travelling around Switzerland

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