There are 7 ways to get from Madrid to Mussomeli by plane, train, bus, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain
8h 9m€88–271Fly to Catania–Fontanarossa Airport, bus
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
9h 34m€68–218Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Gironatrain Ave
- Take the bus from Girona, Estació d'Autobusos to Bresciabus
- Take the train from Brescia to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
40h 6m€385–679Bus
- Take the bus from Madrid to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
2d 1h€261–399Train, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the carferry from Port de Barcelona to Port of Genoacarferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain Re
2d 2h€268–472Fly to Trapani Airport, bus, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Terminal Busbus
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain
11h 47m€140–534Bus via Karlsruhe
- Take the bus from Estación Sur de Autobuses to Karlsruhe - Central Station South Sidebus
- Take the bus from Karlsruhe Central Bus Station to Canicattìbus
- Take the bus from Caltanissetta to Mussomelibus
2d 15h€387–582
Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Madrid to Mussomeli is to fly and bus which costs €65 - €220 and takes 9h 34m.
The fastest way to get from Madrid to Mussomeli is to fly and train which takes 8h 9m and costs €85 - €280.
No, there is no direct bus from Madrid to Mussomeli. However, there are services departing from Madrid and arriving at Mussomeli via Milano, Autostazione Lampugnano and Caltanissetta. The journey, including transfers, takes approximately 2 days 1h.
The distance between Madrid and Mussomeli is 1611 km.
The best way to get from Madrid to Mussomeli without a car is to train and bus which takes 40h 6m and costs €380 - €700.
It takes approximately 8h 9m to get from Madrid to Mussomeli, including transfers.
Madrid to Mussomeli bus services, operated by FlixBus, depart from Madrid station.
Madrid to Mussomeli bus services, operated by FlixBus, arrive at Milan station.
There are 178+ hotels available in Mussomeli.
What companies run services between Madrid, Spain and Mussomeli, Italy?
You can take a bus from Madrid to Mussomeli via Milano, Autostazione Lampugnano, Caltanissetta, and Caltanissetta in around 2d 1h.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday, Friday, Tuesday, and Monday
- Estimated price
- €50–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €50–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 45m
- When
- Thursday, Tuesday, and Sunday
- Estimated price
- €60–310
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 55m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €65–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 7h 10m
- When
- Monday
- Estimated price
- €65–260
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Girona, Estació d'Autobusos to Brescia
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €130–210
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Caltanissetta
- Ave. Duration
- 22h 55m
- Frequency
- Once daily
- Estimated price
- €120–190
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €80–120
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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