There are 7 ways to get from Madrid to Mussomeli by plane, train, bus, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
7h 51m€101–242Fly to Catania–Fontanarossa Airport, bus
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
9h 34m€63–219Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the bus from Barcelona to Genoabus
- Take the bus from Genoa to Naplesbus
- Take the train from Napoli Centrale to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Cammarata-S.G.Geminitrain Re
39h 49m€280–613Train, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the car ferry from Port de Barcelona to Port of Genoacarferry
- Take the car ferry from Port of Genoa to Port of Palermocarferry
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain Re
2d 2h€278–488Fly to Trapani Airport, bus, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Airport Bus Stopbus
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
11h 56m€116–300Bus, train
- Take the bus from Madrid to Milanbus
- Take the bus from Milan Lampugnano to Catania Via D'Amico Bus Stationbus
- Take the train from Catania Centrale to Caltanissetta C.Letrain Re
- Take the bus from Caltanissetta to Mussomelibus
2d 1h€243–427Bus
- Take the bus from Madrid to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
2d 1h€263–442
Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Madrid to Mussomeli is to fly and bus which costs €60 - €220 and takes 9h 34m.
The fastest way to get from Madrid to Mussomeli is to fly and train which takes 7h 51m and costs €100 - €250.
No, there is no direct bus from Madrid to Mussomeli. However, there are services departing from Madrid and arriving at Mussomeli via Milano, Autostazione Lampugnano and Caltanissetta. The journey, including transfers, takes approximately 2 days 1h.
The distance between Madrid and Mussomeli is 1603 km.
The best way to get from Madrid to Mussomeli without a car is to train and bus which takes 39h 49m and costs €280 - €650.
It takes approximately 7h 51m to get from Madrid to Mussomeli, including transfers.
Madrid to Mussomeli bus services, operated by FlixBus, depart from Madrid station.
Madrid to Mussomeli bus services, operated by FlixBus, arrive at Milan station.
There are 173+ hotels available in Mussomeli.
What companies run services between Madrid, Spain and Mussomeli, Italy?
You can take a bus from Madrid to Mussomeli via Milano, Autostazione Lampugnano, Caltanissetta, and Caltanissetta in around 2d 1h.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday to Thursday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €50–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €65–230
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 5h 5m
- When
- Thursday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 55m
- When
- Monday to Friday
- Estimated price
- €65–230
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €50–240
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 22m
- When
- Wednesday, Friday, Monday, and Tuesday
- Estimated price
- €45–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €60–130
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €50–240
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 22m
- When
- Wednesday, Friday, Monday, and Tuesday
- Estimated price
- €45–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €60–130
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €90–290
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- €15–25
- Website
- https://www.trenitalia.com/en.html
Train from Termini Imerese to Cammarata-S.G.Gemini
- Ave. Duration
- 38 min
- Frequency
- Every 4 hours
- Estimated price
- €6–11
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 31m
- Frequency
- 3 times a day
- Estimated price
- €12–20
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- €15–25
- Website
- https://www.trenitalia.com/en.html
Train from Catania Centrale to Caltanissetta C.Le
- Ave. Duration
- 2h 2m
- Frequency
- Every 2 hours
- Estimated price
- €15–25
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Napoli Centrale to Termini Imerese
- Ave. Duration
- 8h 46m
- Frequency
- Twice daily
- Estimated price
- €65–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Barcelona to Genoa
- Ave. Duration
- 13h 10m
- Frequency
- 3 times a day
- Estimated price
- €70–130
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Naples
- Ave. Duration
- 9h 20m
- Frequency
- Twice daily
- Estimated price
- €60–110
- Website
- https://www.flixbus.co.uk
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €130–230
- Website
- https://www.flixbus.co.uk
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €130–230
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Caltanissetta
- Ave. Duration
- 22h 55m
- Frequency
- Once daily
- Estimated price
- €120–210
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Barcelona to Genoa
- Ave. Duration
- 12h 50m
- Frequency
- Twice daily
- Estimated price
- €75–140
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Genoa to Naples
- Ave. Duration
- 8h 50m
- Frequency
- 4 times a week
- Estimated price
- €45–85
- Website
- https://www.itabus.it/en/home
Bus from Milan Lampugnano to Catania Via D'Amico Bus Station
- Ave. Duration
- 19h 50m
- Frequency
- Twice daily
- Estimated price
- €85–170
- Website
- https://www.itabus.it/en/home
- Phone
- +39 0912742800
- [email protected]
- Website
- saistrasporti.it
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- https://saistrasporti.it/en-US
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- https://saistrasporti.it/en-US
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- https://saistrasporti.it/en-US
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- https://saistrasporti.it/en-US
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Trapani Birgi Airport to Palermo Airport Bus Stop
- Ave. Duration
- 1h 10m
- Frequency
- 5 times a week
- Estimated price
- €5–8
- Schedules at
- autoservizisalemi.it
- Phone
- +39 010 209 4591
- [email protected]
- Website
- gnv.it
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €80–120
- Website
- https://www.gnv.it/en
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
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