There are 8 ways to get from Madrid to Mussomeli by plane, train, bus, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Adolfo Suárez Madrid–Barajas Airport to Palermo Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
7h 52m€100–286Fly Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport, bus
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
9h 34m€63–218Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Gironatrain Ave
- Take the bus from Girona, Estació d'Autobusos to Bresciabus
- Take the train from Brescia to Roma Terminitrain
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
40h 3m€355–639Bus
- Take the bus from Madrid to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
2d 1h€275–416Train, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the carferry from Port de Barcelona to Port of Genoacarferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain Re
2d 2h€268–471Fly Adolfo Suárez Madrid–Barajas Airport to Trapani Airport, bus, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Terminal Busbus
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain
12h 12m€140–534Train to Valencia Airport, fly to Palermo Airport, train
- Take the train from Madrid Chamartín to Valencia Joaquin Sorollatrain
- Fly from Valencia Airport (VLC) to Palermo Airport (PMO)plane VLC - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
9h 49m€126–372Bus via Karlsruhe
- Take the bus from Estación Sur de Autobuses to Karlsruhe - Central Station South Sidebus
- Take the bus from Karlsruhe Central Bus Station to Canicattìbus
- Take the bus from Caltanissetta to Mussomelibus
2d 14h€392–593
Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Madrid to Mussomeli is to fly and bus which costs €60 - €220 and takes 9h 34m.
The fastest way to get from Madrid to Mussomeli is to fly and train which takes 7h 52m and costs €100 - €290.
No, there is no direct bus from Madrid to Mussomeli. However, there are services departing from Madrid and arriving at Mussomeli via Milano, Autostazione Lampugnano and Caltanissetta. The journey, including transfers, takes approximately 2 days 1h.
The distance between Madrid and Mussomeli is 1603 km.
The best way to get from Madrid to Mussomeli without a car is to train and bus which takes 40h 3m and costs €350 - €650.
It takes approximately 7h 52m to get from Madrid to Mussomeli, including transfers.
Madrid to Mussomeli bus services, operated by FlixBus, depart from Madrid station.
Madrid to Mussomeli bus services, operated by FlixBus, arrive at Milan station.
There are 181+ hotels available in Mussomeli.
What companies run services between Madrid, Spain and Mussomeli, Italy?
You can take a bus from Madrid to Mussomeli via Milano, Autostazione Lampugnano, Caltanissetta, and Caltanissetta in around 2d 1h.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €50–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €45–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €45–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 4h 57m
- When
- Monday and Saturday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Verona
- Ave. Duration
- 5h 15m
- When
- Sunday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 8h 12m
- When
- Friday and Thursday
- Estimated price
- €60–300
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Sevilla
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- €65–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 7h 15m
- When
- Friday and Saturday
- Estimated price
- €85–340
Flights from Valencia Airport to Palermo Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €40–170
Flights from Valencia Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Tuesday
- Estimated price
- €40–170
Flights from Valencia Airport to Palermo Airport via Pisa
- Ave. Duration
- 4h 15m
- When
- Friday and Sunday
- Estimated price
- €40–170
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Saturday
- Estimated price
- €110–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 25m
- When
- Thursday to Sunday
- Estimated price
- €70–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Wednesday, Thursday, Saturday, and Tuesday
- Estimated price
- €140–310
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 17m
- When
- Thursday to Sunday
- Estimated price
- €70–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Wednesday, Thursday, Saturday, and Tuesday
- Estimated price
- €140–310
- Website
- flyulendo.com
Flights from Valencia Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 35m
- When
- Saturday
- Estimated price
- €40–190
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 51m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 51m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Girona
- Ave. Duration
- 4h 12m
- Frequency
- Every 4 hours
- Estimated price
- €100–190
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h 4m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Renfe AVE
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Girona
- Ave. Duration
- 4h 22m
- Frequency
- Twice daily
- Estimated price
- €90–130
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h 4m
- Frequency
- 5 times a day
- Estimated price
- €50–75
- Website
- Renfe Viajeros
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Brescia to Roma Termini
- Ave. Duration
- 4h 11m
- Frequency
- Every 4 hours
- Estimated price
- €60–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- 4 times a day
- Estimated price
- €85–170
- Website
- Trenitalia Intercity
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Iryo
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 27m
- Frequency
- Hourly
- Estimated price
- €45–80
- Website
- Ouigo
Train from Madrid Chamartín to Valencia Joaquin Sorolla
- Ave. Duration
- 2h 1m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- Ouigo
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Girona, Estació d'Autobusos to Brescia
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Caltanissetta
- Ave. Duration
- 22h 55m
- Frequency
- Once daily
- Estimated price
- €130–200
- Website
- Flixbus
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Terminal Bus
- Ave. Duration
- 1h 55m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Karlsruhe - Central Station South Side
- Ave. Duration
- 26h 15m
- Frequency
- 3 times a day
- Estimated price
- €130–230
- Website
- BlaBlaCar Bus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Karlsruhe Central Bus Station to Canicattì
- Ave. Duration
- 31h 50m
- Frequency
- Once a week
- Estimated price
- €250–360
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €80–120
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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