There are 7 ways to get from Madrid to Palermo by plane, train, bus, ferry, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
5h 38m€54–189Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille St Charles to Toulontrain Ter
- Take the bus from Toulon - Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the train from Genova P.Za Principe to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
33h 52m€328–662Train, ferry, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Genoaferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
39h 34m€251–462Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
46h€250–420Fly to Trapani Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
9h 5m€117–472Train, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the carferry from Port de Barcelona to Port of Genoacarferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
47h 12m€248–459Bus, train
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the train from Padova to Verona Porta Nuovatrain Fr
- Take the bus from Verona Porta Nuova Station to Palermo Piazza Cairolibus
2d 5h
Madrid to Palermo by train and bus
Questions & Answers
The cheapest way to get from Madrid to Palermo is to fly which costs €50 - €190 and takes 5h 38m.
The fastest way to get from Madrid to Palermo is to fly which takes 5h 38m and costs €50 - €190.
No, there is no direct bus from Madrid to Palermo. However, there are services departing from Madrid and arriving at Palermo via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 46h.
The distance between Madrid and Palermo is 1497 km.
The best way to get from Madrid to Palermo without a car is to train and bus which takes 33h 52m and costs €320 - €700.
It takes approximately 5h 38m to get from Madrid to Palermo, including transfers.
Madrid to Palermo bus services, operated by FlixBus, depart from Madrid station.
The best way to get from Madrid to Palermo is to fly which takes 5h 38m and costs €50 - €190. Alternatively, you can bus, which costs €250 - €420 and takes 46h.
Madrid to Palermo bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Madrid, Spain and Palermo, Italy?
Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Madrid to Palermo via Milano, Autostazione Lampugnano in around 46h.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday to Thursday
- Estimated price
- €50–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €70–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €65–250
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 45m
- When
- Thursday, Tuesday, and Sunday
- Estimated price
- €65–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 55m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €70–260
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €40–180
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €40–180
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €80–130
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €80–130
- Website
- Renfe Viajeros
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Marseille St Charles to Toulon
- Ave. Duration
- 57 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–23
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Marseille St Charles to Toulon
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Website
- Zou! Lignes Express Régionales
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Marseille St Charles to Toulon
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €13–22
- Website
- TGV inOui
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 4h 56m
- Frequency
- Hourly
- Estimated price
- €70–150
- Schedules at
- Trenitalia Frecce
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–24
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 5h 40m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 38m
- Frequency
- Twice daily
- Estimated price
- €90–200
- Website
- Trenitalia Intercity
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Ouigo
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- 4 times a day
- Estimated price
- €25–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €25–35
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 1h 54m
- Frequency
- Every 30 minutes
- Estimated price
- €10–17
- Website
- Trenitalia
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Toulon - Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- €30–55
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €130–210
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €120–210
- Website
- Flixbus
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodi
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Verona Porta Nuova Station to Palermo Piazza Cairoli
- Ave. Duration
- 23h 57m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 13h 5m
- Frequency
- 3 times a week
- Estimated price
- €85–130
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €85–130
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in Spain: A guide to Renfe
Read the travel guide
More Questions & Answers
There are 6395+ hotels available in Palermo.





























































