There are 7 ways to get from Madrid to Palermo by plane, train, bus, ferry, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
5h 38m€54–179Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille St Charles to Toulontrain Ter
- Take the bus from Toulon to Florencebus
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
33h 4m€321–604Train, ferry, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the car ferry from Civitavecchia Port to Palermo Portocarferry
39h 8m€191–382Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
46h€266–443Fly to Trapani Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
9h 5m€67–232Train, ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Civitavecchia to Palermoferry
39h 27m€181–382Bus, train
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the train from Padova to Verona Porta Nuovatrain Fr
- Take the bus from Verona Porta Nuova Station to Palermo Piazza Cairolibus
2d 5h
Madrid to Palermo by train, bus, and foot
Questions & Answers
The cheapest way to get from Madrid to Palermo is to fly which costs €50 - €180 and takes 5h 38m.
The fastest way to get from Madrid to Palermo is to fly which takes 5h 38m and costs €50 - €180.
No, there is no direct bus from Madrid to Palermo. However, there are services departing from Madrid and arriving at Palermo via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 46h.
The distance between Madrid and Palermo is 1497 km.
The best way to get from Madrid to Palermo without a car is to train and bus which takes 33h 4m and costs €320 - €650.
It takes approximately 5h 38m to get from Madrid to Palermo, including transfers.
Madrid to Palermo bus services, operated by FlixBus, depart from Madrid station.
The best way to get from Madrid to Palermo is to fly which takes 5h 38m and costs €50 - €180. Alternatively, you can bus, which costs €260 - €450 and takes 46h.
Madrid to Palermo bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Madrid, Spain and Palermo, Italy?
Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Madrid to Palermo via Milano, Autostazione Lampugnano in around 46h.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday to Thursday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €65–230
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 5h 5m
- When
- Thursday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 55m
- When
- Monday to Friday
- Estimated price
- €65–230
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €50–240
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 22m
- When
- Wednesday, Friday, Monday, and Tuesday
- Estimated price
- €45–190
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €50–240
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 22m
- When
- Wednesday, Friday, Monday, and Tuesday
- Estimated price
- €45–190
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €90–290
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–220
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Marseille St Charles to Toulon
- Ave. Duration
- 57 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–22
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 4 13 94 30 50
- Website
- zou.maregionsud.fr
Train from Marseille St Charles to Toulon
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Website
- https://zou.maregionsud.fr/en/
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Marseille St Charles to Toulon
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €14–23
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 20 minutes
- Estimated price
- €35–80
- Schedules at
- trenitalia.com
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–24
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 52m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €10–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Twice daily
- Estimated price
- €90–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- [email protected]
- Website
- trenitalia.com
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- 4 times a day
- Estimated price
- €25–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €25–35
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Toulon to Florence
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- €45–80
- Website
- https://www.flixbus.co.uk
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €130–230
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €130–220
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodi
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- autoservizisalemi.it
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Verona Porta Nuova Station to Palermo Piazza Cairoli
- Ave. Duration
- 23h 57m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +39.081.496.444
- [email protected]
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €75–130
- Website
- https://www.grimaldi-lines.com/en/
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €75–130
- Website
- https://www.grimaldi-lines.com/en/
- Phone
- +39 010 209 4591
- [email protected]
- Website
- gnv.it
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €55–85
- Website
- https://www.gnv.it/en
Ferry from Civitavecchia to Palermo
- Ave. Duration
- 13h 45m
- Frequency
- Once a week
- Estimated price
- €45–85
- Website
- https://www.gnv.it/en
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