There are 7 ways to get from Madrid to Palermo by plane, train (Renfe, Ouigo, Trenitalia), bus, train, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
5h 38m€54–198Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Oulx-Cesana-Clav.-S.train Fr
- Take the train from Oulx-Cesana-Clav.-S. to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
32h 38m€373–758Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
46h€244–398Train, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the carferry from Port de Barcelona to Port of Genoacarferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
46h 52m€248–446Fly to Trapani Airport, bus
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
9h 5m€72–272Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille St Charles to Toulontrain Ter
- Take the bus from Toulon - Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the train from Genova P.Za Principe to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
33h 46m€329–654Bus via Milan
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano - Famagosta to Palermo Piazza Cairolibus
47h 18m€337–493
Madrid to Palermo by train
Questions & Answers
The cheapest way to get from Madrid to Palermo is to fly which costs €50 - €200 and takes 5h 38m.
The fastest way to get from Madrid to Palermo is to fly which takes 5h 38m and costs €50 - €200.
No, there is no direct bus from Madrid to Palermo. However, there are services departing from Madrid and arriving at Palermo via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 46h.
No, there is no direct train from Madrid to Palermo. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Palermo Centrale via Barcelona-Sants, Lyon Part Dieu, Oulx-Cesana-Clav.-S. and Roma Termini. The journey, including transfers, takes approximately 32h 38m.
The distance between Madrid and Palermo is 1497 km.
The best way to get from Madrid to Palermo without a car is to train which takes 32h 38m and costs €370 - €800.
It takes approximately 5h 38m to get from Madrid to Palermo, including transfers.
Madrid to Palermo bus services, operated by FlixBus, depart from Madrid station.
Madrid to Palermo train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Palermo is to fly which takes 5h 38m and costs €50 - €200. Alternatively, you can train, which costs €370 - €800 and takes 32h 38m, you could also bus, which costs €240 - €400 and takes 46h.
What companies run services between Madrid, Spain and Palermo, Italy?
Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) 4 times a day. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Palermo Centrale via Barcelona-Sants, Lyon Part Dieu, Oulx-Cesana-Clav.-S., and Roma Termini in around 32h 38m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday to Thursday
- Estimated price
- €50–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €65–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 45m
- When
- Thursday, Tuesday, and Sunday
- Estimated price
- €65–310
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 55m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €70–270
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €85–130
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
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More Questions & Answers
Madrid to Palermo bus services, operated by FlixBus, arrive at Milan station.
Madrid to Palermo train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Book your Madrid to Palermo train tickets online with Omio.
Book your Madrid to Palermo bus tickets online with Omio and FlixBus.
There are 6308+ hotels available in Palermo.
















