There are 9 ways to get from Madrid to Saint-Louis by plane, train (Renfe, TGV), bus, car, train, or train (Renfe, Ouigo, TGV)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Basel
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Basel (BSL)plane MAD - BSL
4h 50m€66–212Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgvtrain 9725
- Take the train from Avignon Tgv to Mulhouse Villetrain Tgv
13h 34m€240–423Bus via Lyon
- Take the bus from Madrid to Lyonbus FlixBus N1149
- Take the bus from Lyon to Basel SBBbus FlixBus N122 / ...
25h 11m€136–225Drive 1,498.7 km
- Drive from Madrid to Saint-Louiscar 1,498.7 km
15h 16m€235–339Fly to Zurich Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Zurich Airport (ZRH)plane MAD - ZRH
- Take the train from Zürich HB to Basel SBBtrain
6h 41m€111–326Fly to Strasbourg International Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Strasbourg International Airport (SXB)plane MAD - SXB
- Take the train from Strasbourg to St Louistrain
6h 10m€114–300Fly to Geneva International Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Geneva International Airport (GVA)plane MAD - GVA
- Take the train from Genève-Aéroport to Renens VDtrain
- Take the train from Renens VD to Basel SBBtrain
8h 47m€145–495Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Mulhouse Villetrain Tgv
13h 56m€223–435Bus
- Take the bus from Estación Sur de Autobuses to Strasbourg - L'Étoile Park Bus Stationbus BlaBlaCar Bus
- Take the bus from Strasbourg to Basel Euroairport FRbus FlixBus 108 / ...
28h€171–305
Madrid to Saint-Louis by train
Questions & Answers
The cheapest way to get from Madrid to Saint-Louis is to fly which costs €65 - €220 and takes 4h 50m.
The fastest way to get from Madrid to Saint-Louis is to fly which takes 4h 50m and costs €65 - €220.
No, there is no direct bus from Madrid to Saint-Louis. However, there are services departing from Madrid and arriving at Basel SBB via Lyon. The journey, including transfers, takes approximately 25h 11m.
No, there is no direct train from Madrid to Saint-Louis. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at St Louis via Avignon Tgv and Mulhouse Ville. The journey, including transfers, takes approximately 13h 34m.
The distance between Madrid and Saint-Louis is 1202 km. The road distance is 1498.7 km.
The best way to get from Madrid to Saint-Louis without a car is to train which takes 13h 34m and costs €240 - €430.
It takes approximately 4h 50m to get from Madrid to Saint-Louis, including transfers.
Madrid to Saint-Louis bus services, operated by FlixBus, depart from Madrid station.
Madrid to Saint-Louis train services, operated by Renfe Viajeros, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Saint-Louis is to fly which takes 4h 50m and costs €65 - €220. Alternatively, you can train, which costs €240 - €430 and takes 13h 34m, you could also bus via Lyon, which costs €130 - €230 and takes 25h 11m.
What companies run services between Madrid, Spain and Saint-Louis, Grand Est, France?
easyJet flies from Adolfo Suárez Madrid–Barajas Airport (MAD) to Basel (BSL) 6 times a week. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to St Louis via Avignon Tgv and Mulhouse Ville in around 13h 34m.
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €65–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Strasbourg International Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €130–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Geneva International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- €60–160
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- €65–200
Flights from Adolfo Suárez Madrid–Barajas Airport to Geneva International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- €55–190
- Website
- easyjet.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Basel
- Ave. Duration
- 2h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €55–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Geneva International Airport
- Ave. Duration
- 2h
- When
- Monday
- Estimated price
- €40–270
- Website
- swiss.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- €75–200
- Website
- volotea.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Strasbourg International Airport via Bordeaux
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- €95–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Strasbourg International Airport via Montpellier
- Ave. Duration
- 5h 30m
- When
- Friday
- Estimated price
- €95–280
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgv
- Ave. Duration
- 8h 2m
- Frequency
- Twice daily
- Estimated price
- €130–210
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- €80–130
- Website
- Renfe Viajeros
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Mulhouse Ville
- Ave. Duration
- 4h 1m
- Frequency
- Every 3 hours
- Estimated price
- €120–200
- Website
- TGV inOui
Train from Lyon Part Dieu to Mulhouse Ville
- Ave. Duration
- 3h 8m
- Frequency
- Hourly
- Estimated price
- €80–130
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Mulhouse Ville
- Ave. Duration
- 4h 1m
- Frequency
- Once daily
- Estimated price
- €100–210
- Website
- Oui.SNCF
Train from Strasbourg to St Louis
- Ave. Duration
- 1h 9m
- Frequency
- Every 30 minutes
- Estimated price
- €22–45
- Website
- Oui.SNCF
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–95
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Genève-Aéroport to Renens VD
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €22–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Basel SBB
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €60–190
- Website
- Swiss Federal Railways (SBB CFF FFS)
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Ouigo
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Madrid to Lyon
- Ave. Duration
- 17h 55m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Flixbus
Bus from Lyon to Basel SBB
- Ave. Duration
- 5h 45m
- Frequency
- Twice daily
- Estimated price
- €30–55
- Website
- Flixbus
Bus from Strasbourg to Basel Euroairport FR
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a day
- Estimated price
- €11–19
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Strasbourg - L'Étoile Park Bus Station
- Ave. Duration
- 24h 20m
- Frequency
- Once daily
- Estimated price
- €160–290
- Website
- BlaBlaCar Bus
Bus from Strasbourg to Basel Euroairport FR
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- €12–22
- Website
- BlaBlaCar Bus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Madrid to Saint-Louis bus services, operated by FlixBus, arrive at Lyon station.
Madrid to Saint-Louis train services, operated by Renfe Viajeros, arrive at Avignon Tgv station.
Yes, the driving distance between Madrid to Saint-Louis is 1499 km. It takes approximately 15h 16m to drive from Madrid to Saint-Louis.
Book your Madrid to Saint-Louis train tickets online with Omio.
Book your Madrid to Saint-Louis bus tickets online with Omio.
There are 2013+ hotels available in Saint-Louis.


































