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How to get fromMadrid to Santa Cruz de la Sierraby bus, train, or car

Find Transport to Santa Cruz de la Sierra

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There are 4 ways to get from Madrid to Santa Cruz de la Sierra by bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Madrid Estación Sur de Autobuses to Trujillobus bus
    4h 20m
    €20–39

  2. Train, bus

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Navalmoral De La Matatrain train Alv / ...
    2. Take the bus from Navalmoral de la Mata to Trujillobus bus
    5h 11m
    €32–56

  3. Drive 268.5 km

    1. Drive from Madrid to Santa Cruz de la Sierracar car 268.5 km
    2h 37m
    €43–61

  4. Bus via Escurial

    1. Take the bus from Estación Sur de Autobuses to Escurialbus bus 902
    6h 35m
    €31–46

Madrid to Santa Cruz de la Sierra by bus

Calendar4Weekly Buses
Duration4h 20mAverage Duration
Ticket€20Cheapest Price
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Questions & Answers

Map of how to get from Madrid to Santa Cruz de la Sierra.ExpandLaunch map view
  • Distance: 275.6 km
  • Duration: 4h 20m

What companies run services between Madrid, Spain and Santa Cruz de la Sierra, Spain?

Interbus operates a bus from Madrid Estación Sur de Autobuses to Trujillo 4 times a week. Tickets cost €18–40 and the journey takes 3h 5m.

Train operators
Bus operators

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