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How to get fromMadrid to Santanderaby train (Renfe, Ouigo), bus, car, or train (Renfe)

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There are 4 ways to get from Madrid to Santandera by train (Renfe, Ouigo), bus, car, or train (Renfe)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Valladolid

    best
    1. Take the train from Madrid Chamartín to Valladolidtrain train Avn / ...
    2. Take the train from Valladolid to Villaquirantrain train 18063 / ...
    3h 48m
    €58–105
  2. Drive 252.1 km

    cheapest
    1. Drive from Madrid to Santanderacar car 252.1 km
    3h
    €40–58
  3. Bus

    1. Take the bus from Madrid, Avenida de América to Estación de autobuses de Burgosbus bus ALSA - Mad-San / ...
    2. Take the bus from Estación de autobuses de Burgos to Hontanasbus bus
    5h 8m
    €45–71
  4. Train (Renfe)

    1. Take the train from Madrid-Principe Pio to Villaquirantrain train 18063 / ...
    4h 43m
    €75–107

Questions & Answers

What companies run services between Madrid, Spain and Santandera, Spain?

You can take a train from Madrid Chamartín to Santandera via Valladolid and Villaquiran in around 3h 48m. Alternatively, you can take a bus from Madrid, Avenida de América to Santandera via Estación de autobuses de Burgos and Hontanas in around 5h 8m.

Train operators
Bus operators

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