There are 8 ways to get from Madrid to Sicily by plane, train, bus, car ferry, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
5h 38m€54–199Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the bus from Barcelona to Florencebus
- Take the bus from Florence Villa Constanza Bus Station to Naples Metropark Central Parkingbus 30 / ...
- Take the train from Napoli Centrale to Palermo Centraletrain Ic
36h 32m€242–519Train, bus, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille to Genoabus
- Take the carferry from Port of Genoa to Port of Palermocarferry
38h 40m€279–424Fly to Catania–Fontanarossa Airport
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
5h 17m€55–196Fly to Trapani Airport
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane MAD - TPS
8h 10m€104–465Train, ferry, car ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Genoaferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
40h 2m€247–442Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
46h 31m€235–401Bus via Strasbourg
- Take the bus from Estación Sur de Autobuses to Strasbourg - L'Étoile Park Bus Stationbus
- Take the bus from Strasbourg to Palermo Piazza Cairolibus
2d 9h€430–650
Madrid to Sicily by train, foot, and bus
Questions & Answers
The cheapest way to get from Madrid to Sicily is to fly which costs €55 - €200 and takes 5h 17m.
The fastest way to get from Madrid to Sicily is to fly which takes 5h 17m and costs €55 - €200.
No, there is no direct bus from Madrid to Sicily. However, there are services departing from Madrid and arriving at Piazza Boiardo via Milano, Autostazione Lampugnano and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 46h 31m.
The distance between Madrid and Sicily is 1497 km.
The best way to get from Madrid to Sicily without a car is to train and bus which takes 36h 32m and costs €240 - €550.
It takes approximately 5h 38m to get from Madrid to Sicily, including transfers.
Madrid to Sicily bus services, operated by FlixBus, depart from Madrid station.
The best way to get from Madrid to Sicily is to fly which takes 5h 38m and costs €50 - €200. Alternatively, you can bus, which costs €230 - €410 and takes 46h 31m.
Madrid to Sicily bus services, operated by FlixBus, arrive at Milan station.
There are 6320+ hotels available in Sicily.
What companies run services between Madrid, Spain and Sicily, Italy?
Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Madrid to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 46h 31m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Wednesday to Thursday
- Estimated price
- €50–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €50–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 30m
- When
- Sunday and Monday
- Estimated price
- €70–270
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Pisa
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €65–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Rome
- Ave. Duration
- 4h 45m
- When
- Thursday, Tuesday, and Sunday
- Estimated price
- €65–300
Flights from Adolfo Suárez Madrid–Barajas Airport to Trapani Airport via Bologna
- Ave. Duration
- 6h 50m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €70–260
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 20m
- When
- Tuesday, Wednesday, and Friday
- Estimated price
- €45–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €60–140
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €120–800
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 4h 20m
- When
- Tuesday, Wednesday, and Friday
- Estimated price
- €45–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €60–140
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 20 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 20 minutes
- Estimated price
- €90–160
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- Renfe Viajeros
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Napoli Centrale to Palermo Centrale
- Ave. Duration
- 9h 18m
- Frequency
- 3 times a day
- Estimated price
- €70–150
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Barcelona to Florence
- Ave. Duration
- 14h 30m
- Frequency
- Twice daily
- Estimated price
- €80–140
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Naples Metropark Central Parking
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Marseille to Genoa
- Ave. Duration
- 6h 20m
- Frequency
- Every 4 hours
- Estimated price
- €29–50
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €110–200
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Florence Villa Constanza Bus Station to Naples Metropark Central Parking
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- €30–70
- Website
- Itabus S.p.A.
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Strasbourg - L'Étoile Park Bus Station
- Ave. Duration
- 24h 20m
- Frequency
- Once daily
- Estimated price
- €150–280
- Website
- BlaBlaCar Bus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Strasbourg to Palermo Piazza Cairoli
- Ave. Duration
- 31h 24m
- Frequency
- Once a week
- Estimated price
- €270–370
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 13h 5m
- Frequency
- 3 times a week
- Estimated price
- €80–130
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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