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How to get fromMadrid to Sicilyby plane, train, bus, car ferry, or ferry

Find Transport to Sicily

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There are 8 ways to get from Madrid to Sicily by plane, train, bus, car ferry, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane plane MAD - PMO
    5h 38m
    €54–226

  2. Train, bus, car ferry

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the bus from Marseille to Genoabus bus
    3. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    38h 40m
    €277–409

  3. Train, bus

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Gironatrain train Ave
    2. Take the bus from Girona, Estació d'Autobusos to Bresciabus bus
    3. Take the train from Brescia to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    39h 24m
    €362–654

  4. Bus

    1. Take the bus from Madrid to Milanbus bus FlixBus N1138
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    46h 31m
    €269–405

  5. Fly to Catania–Fontanarossa Airport

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane plane MAD - CTA
    5h 17m
    €60–205

  6. Fly to Trapani Airport

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Trapani Airport (TPS)plane plane MAD - TPS
    8h 10m
    €104–484

  7. Train, ferry, car ferry

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the ferry from Port de Barcelona to Port of Genoaferry ferry
    3. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    40h 2m
    €236–430

  8. Bus via Strasbourg

    1. Take the bus from Estación Sur de Autobuses to Strasbourg - L'Étoile Park Bus Stationbus bus
    2. Take the bus from Strasbourg to Palermo Piazza Cairolibus bus
    2d 9h
    €399–587

Madrid to Sicily by train and bus

Calendar2Weekly Services
Duration39h 24mAverage Duration
Ticket€362Cheapest Price
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Comparing Your Travel Options

Map of how to get from Madrid to Sicily.ExpandLaunch map view
  • Distance: 1,497.2 km
  • Duration: 5h 38m

What companies run services between Madrid, Spain and Sicily, Italy?

Ryanair, Iberia, and Vueling Airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Madrid to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 46h 31m.

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