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How to get fromMadrid to Sienaby plane, train, train (Renfe, Ouigo, Trenitalia), bus, or car

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There are 10 ways to get from Madrid to Siena by plane, train, train (Renfe, Ouigo, Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane plane MAD - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 2m
    €74–173

  2. Fly to Fiumicino International Airport, train

    cheapest
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Fiumicino International Airport (FCO)plane plane MAD - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 47m
    €73–228

  3. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 21m
    €234–493

  4. Bus via Genoa

    1. Take the bus from Madrid to Genoabus bus
    2. Take the bus from Genoa to Florence Villa Constanza Bus Stationbus bus 510 / ...
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    26h 28m
    €147–249

  5. Drive 1,676.8 km

    1. Drive from Madrid to Sienacar car 1,676.8 km
    17h 19m
    €265–383

  6. Fly to Pisa International Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane plane MAD - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    6h 45m
    €78–212

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MAD - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 22m
    €81–208

  8. Fly to Venice Marco Polo Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Venice Marco Polo Airport (VCE)plane plane MAD - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 25m
    €73–233

  9. Train, bus

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain train
    3. Take the bus from Nice - Airport Bus Station Terminal 1 to Sienabus bus
    21h 22m
    €249–411

  10. Bus

    1. Take the bus from Méndez Álvaro Estación Sur to Padovabus bus
    2. Take the bus from Padova to Florencebus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    33h 13m
    €156–186

Madrid to Siena by train

Calendar14Weekly Trains
Duration19h 21mAverage Duration
Ticket€234Cheapest Price
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Questions & Answers

Map of how to get from Madrid to Siena.ExpandLaunch map view
  • Distance: 1,380 km
  • Duration: 7h 2m

What companies run services between Madrid, Spain and Siena, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Siena via Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 19h 21m. Alternatively, you can take a bus from Madrid to Siena via Genoa and Florence Villa Constanza Bus Station in around 26h 28m.

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