There are 7 ways to get from Madrid to Syracuse by plane, bus, train, night train, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 12m€55–210Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille St Charles to Toulontrain Ter
- Take the bus from Toulon - Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus
- Take the train from Genova P.Za Principe to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Siracusatrain Ic
33h 30m€322–641Bus
- Take the bus from Madrid to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Cataniabus
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
44h 31m€268–443Train, bus, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille to Genoabus
- Take the train from Genova P.Za Principe to Piacenzatrain Ic
- Take the night train from Piacenza to Siracusanighttrain Ini
39h 20m€315–561Train, ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Genoaferry
- Take the train from Genova P.Za Principe to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Siracusatrain Ic
35h 52m€284–632Bus via Padova
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the bus from Padova to Bologna, P.zza Venti Settembrebus
- Take the bus from Bologna Autostazione to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
2d 1h€219–332Drive, car ferry
- Drive from Madrid to Villa S. Giovannicar
- Take the car ferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
27h 1m€449–657
Madrid to Syracuse by train and bus
Questions & Answers
The cheapest way to get from Madrid to Syracuse is to fly and bus which costs €55 - €210 and takes 6h 12m.
The fastest way to get from Madrid to Syracuse is to fly and bus which takes 6h 12m and costs €55 - €210.
No, there is no direct bus from Madrid to Syracuse. However, there are services departing from Madrid and arriving at Siracusa - Von Platen via Milano, Autostazione Lampugnano and Catania Via Archimede. The journey, including transfers, takes approximately 44h 31m.
The distance between Madrid and Syracuse is 1712 km.
The best way to get from Madrid to Syracuse without a car is to train and bus which takes 33h 30m and costs €320 - €650.
It takes approximately 6h 12m to get from Madrid to Syracuse, including transfers.
Madrid to Syracuse bus services, operated by FlixBus, depart from Madrid station.
Madrid to Syracuse bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Syracuse bus tickets online with Omio.
There are 3322+ hotels available in Syracuse.
What companies run services between Madrid, Spain and Syracuse, Italy?
You can take a bus from Madrid to Siracusa - Von Platen via Milano, Autostazione Lampugnano, Catania, and Catania Via Archimede in around 44h 31m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 50m
- When
- Thursday
- Estimated price
- €50–220
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €60–130
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Marseille St Charles to Toulon
- Ave. Duration
- 57 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–22
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 4 13 94 30 50
- Website
- zou.maregionsud.fr
Train from Marseille St Charles to Toulon
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Website
- https://zou.maregionsud.fr/en/
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Marseille St Charles to Toulon
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 4h 58m
- Frequency
- Hourly
- Estimated price
- €70–150
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 4h 58m
- Frequency
- Hourly
- Estimated price
- €70–150
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 5h 39m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Twice daily
- Estimated price
- €85–180
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Piacenza
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €14–30
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 5h 39m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Twice daily
- Estimated price
- €85–180
- Website
- https://www.trenitalia.com/en.html
- Phone
- 06 3000
- Website
- trenitalia.com
Night train from Piacenza to Siracusa
- Ave. Duration
- 18h 41m
- Frequency
- 3 times a day
- Estimated price
- €120–250
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €4–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €4–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €4–9
- Schedules at
- interbus.it
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Toulon - Bus Station to Genoa - Via Fanti d'Italia Bus Stop
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- €30–55
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–240
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Catania
- Ave. Duration
- 18h 50m
- Frequency
- Twice daily
- Estimated price
- €120–200
- Website
- https://www.flixbus.co.uk
Bus from Marseille to Genoa
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- €35–60
- Website
- https://www.flixbus.co.uk
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €120–160
- Schedules at
- tabitatour.ro
- Phone
- +39 098 3520 315
- [email protected]
- Website
- simetbus.it
Bus from Padova to Bologna, P.zza Venti Settembre
- Ave. Duration
- 1h 41m
- Frequency
- 3 times a week
- Estimated price
- €19–22
- Schedules at
- simetbus.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Bologna Autostazione to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 16h 50m
- Frequency
- Twice daily
- Estimated price
- €70–150
- Website
- https://www.itabus.it/en/home
- Phone
- +39 010 209 4591
- [email protected]
- Website
- gnv.it
Ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 13h 5m
- Frequency
- 3 times a week
- Estimated price
- €85–130
- Website
- https://www.gnv.it/en
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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