There are 6 ways to get from Madrid to Syracuse by plane, bus, train, night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 17m€53–209Train, bus, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the bus from Barcelona to Florencebus
- Take the nighttrain from Firenze Castello to Catania Centralenighttrain Ini
- Take the bus from Catania Via Archimede to Siracusa - v.le Scala Grecabus
37h 33m€237–462Bus
- Take the bus from Madrid to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Cataniabus
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
44h 31m€269–414Drive, car ferry
- Drive from Madrid to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
27h 1m€508–744Bus, night train
- Take the bus from Madrid to Milanbus
- Take the nighttrain from Milano Centrale to Catania Centralenighttrain Ini
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
45h 15m€261–417Bus via Marseille
- Take the bus from Estación Sur de Autobuses to Marseille - Saint-Charles Bus Stationbus
- Take the bus from Marseille - Saint-Charles Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
2d 1h€213–377
Madrid to Syracuse by train, foot, bus, tram, taxi, and night train
Comparing Your Travel Options
The cheapest way to get from Madrid to Syracuse is to fly and bus which costs €50 - €210 and takes 6h 17m.
The fastest way to get from Madrid to Syracuse is to fly and bus which takes 6h 17m and costs €50 - €210.
No, there is no direct bus from Madrid to Syracuse. However, there are services departing from Madrid and arriving at Siracusa - Von Platen via Milano, Autostazione Lampugnano and Catania Via Archimede. The journey, including transfers, takes approximately 44h 31m.
The distance between Madrid and Syracuse is 1712 km.
The best way to get from Madrid to Syracuse without a car is to train and bus and night train which takes 37h 33m and costs €230 - €470.
It takes approximately 6h 17m to get from Madrid to Syracuse, including transfers.
Madrid to Syracuse bus services, operated by FlixBus, depart from Madrid station.
Madrid to Syracuse bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Syracuse bus tickets online with Omio and 12go.asia.
There are 2837+ hotels available in Syracuse.
What companies run services between Madrid, Spain and Syracuse, Italy?
You can take a bus from Madrid to Siracusa - Von Platen via Milano, Autostazione Lampugnano, Catania, and Catania Via Archimede in around 44h 31m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 40m
- When
- Thursday
- Estimated price
- €45–150
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Saturday
- Estimated price
- €55–140
Rome2Rio's guide to Renfe AVE
Contact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €80–140
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €50–95
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €70–110
- Website
- Renfe Viajeros
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Firenze Castello to Catania Centrale
- Ave. Duration
- 15h 27m
- Frequency
- Once daily
- Estimated price
- €85–150
- Website
- Trenitalia ICN
Night train from Milano Centrale to Catania Centrale
- Ave. Duration
- 18h 50m
- Frequency
- Twice daily
- Estimated price
- €110–190
- Website
- Trenitalia ICN
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - v.le Scala Greca
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €2–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Barcelona to Florence
- Ave. Duration
- 14h 30m
- Frequency
- Twice daily
- Estimated price
- €95–150
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Catania
- Ave. Duration
- 18h 50m
- Frequency
- Once daily
- Estimated price
- €120–190
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Marseille - Saint-Charles Bus Station
- Ave. Duration
- 17h 59m
- Frequency
- 3 times a day
- Estimated price
- €100–170
- Website
- BlaBlaCar Bus
Bus from Marseille - Saint-Charles Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 7h 35m
- Frequency
- Every 3 hours
- Estimated price
- €40–70
- Website
- BlaBlaCar Bus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 20h 10m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- Itabus S.p.A.
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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