There are 7 ways to get from Madrid to Syracuse by plane, bus, train, night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 17m€53–219Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain
- Take the train from Barcelona-Sants to Paris Gare De Lyontrain
- Take the train from Paris Gare De Lyon to Zuerich Hbtrain
- Take the bus from ZÜRICH, Carparkplatz am Sihlquai to Catania Central Bus Stationbus
- Take the bus from Catania Via Archimede to Siracusa - v.le Scala Grecabus
38h 40m€568–933Train, bus, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Perpignantrain
- Take the bus from Perpignan to Montpellierbus
- Take the bus from Montpellier to Bologna Centralebus 482
- Take the nighttrain from Bologna Centrale to Catania Centralenighttrain Ini
- Take the bus from Catania Via Archimede to Siracusa - v.le Scala Grecabus
38h 52m€275–453Drive, car ferry
- Drive from Madrid to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
27h 1m€507–742Bus
- Take the bus from Madrid to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Cataniabus
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
44h 31m€270–414Bus, night train
- Take the bus from Madrid to Milanbus
- Take the nighttrain from Milano Centrale to Catania Centralenighttrain Ini
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
45h 15m€262–427Bus via Marseille
- Take the bus from Estación Sur de Autobuses to Marseille - Saint-Charles Bus Stationbus
- Take the bus from Marseille - Saint-Charles Bus Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
2d 1h€213–364
Madrid to Syracuse by train, bus, foot, and night train
Comparing Your Travel Options
The cheapest way to get from Madrid to Syracuse is to fly and bus which costs €50 - €220 and takes 6h 17m.
The fastest way to get from Madrid to Syracuse is to fly and bus which takes 6h 17m and costs €50 - €220.
No, there is no direct bus from Madrid to Syracuse. However, there are services departing from Madrid and arriving at Siracusa - Von Platen via Milano, Autostazione Lampugnano and Catania Via Archimede. The journey, including transfers, takes approximately 44h 31m.
The distance between Madrid and Syracuse is 1712 km.
The best way to get from Madrid to Syracuse without a car is to train and bus which takes 38h 40m and costs €550 - €950.
It takes approximately 6h 17m to get from Madrid to Syracuse, including transfers.
Madrid to Syracuse bus services, operated by FlixBus, depart from Madrid station.
Madrid to Syracuse bus services, operated by FlixBus, arrive at Milan station.
Book your Madrid to Syracuse bus tickets online with Omio.
There are 2841+ hotels available in Syracuse.
What companies run services between Madrid, Spain and Syracuse, Italy?
You can take a bus from Madrid to Siracusa - Von Platen via Milano, Autostazione Lampugnano, Catania, and Catania Via Archimede in around 44h 31m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 40m
- When
- Thursday
- Estimated price
- €45–150
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Saturday
- Estimated price
- €55–140
Rome2Rio's guide to Renfe AVE
Contact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €80–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Ouigo
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Perpignan
- Ave. Duration
- 5h 5m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Renfe Viajeros
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Barcelona-Sants to Paris Gare De Lyon
- Ave. Duration
- 6h 52m
- Frequency
- Twice daily
- Estimated price
- €210–320
- Website
- TGV inOui
Train from Paris Gare De Lyon to Zuerich Hb
- Ave. Duration
- 4h 4m
- Frequency
- 5 times a day
- Estimated price
- €120–190
- Website
- TGV inOui
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Bologna Centrale to Catania Centrale
- Ave. Duration
- 15h 55m
- Frequency
- Once daily
- Estimated price
- €95–170
- Website
- Trenitalia ICN
Night train from Milano Centrale to Catania Centrale
- Ave. Duration
- 18h 50m
- Frequency
- Once daily
- Estimated price
- €110–200
- Website
- Trenitalia ICN
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - v.le Scala Greca
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €2–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - v.le Scala Greca
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €2–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from ZÜRICH, Carparkplatz am Sihlquai to Catania Central Bus Station
- Ave. Duration
- 20h 6m
- Frequency
- Once a week
- Estimated price
- €190–270
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Perpignan to Montpellier
- Ave. Duration
- 1h 50m
- Frequency
- Every 3 hours
- Estimated price
- €13–20
- Website
- Flixbus
Bus from Montpellier to Bologna Centrale
- Ave. Duration
- 12h 10m
- Frequency
- Once daily
- Estimated price
- €70–110
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Catania
- Ave. Duration
- 18h 50m
- Frequency
- Once daily
- Estimated price
- €120–190
- Website
- Flixbus
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €140–220
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Perpignan to Montpellier
- Ave. Duration
- 2h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €12–20
- Website
- BlaBlaCar Bus
Bus from Estación Sur de Autobuses to Marseille - Saint-Charles Bus Station
- Ave. Duration
- 17h 59m
- Frequency
- 3 times a day
- Estimated price
- €100–170
- Website
- BlaBlaCar Bus
Bus from Marseille - Saint-Charles Bus Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 7h 35m
- Frequency
- Every 3 hours
- Estimated price
- €40–65
- Website
- BlaBlaCar Bus
- Phone
- +34 910 207 007
- Website
- alsa.es
Bus from Perpignan to Montpellier
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €13–20
- Schedules at
- alsa.es
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Perpignan to Montpellier
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- €7–14
- Website
- Itabus S.p.A.
Bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 20h 10m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- Itabus S.p.A.
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
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