Rome2Rio

How to get fromMaine to Iowaby plane, bus (Amtrak, Flixbus, Greyhound), bus, train, or car

Find Transport to Iowa

See all options

There are 8 ways to get from Maine to Iowa by plane, bus (Amtrak, Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Portland (PWM) to Des Moines (DSM)plane plane PWM - DSM
    4h 56m
    $227–979

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Portland (PWM) to Quad City International Airport (MLI)plane plane PWM - MLI
    6h 34m
    $124–581

  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 16m
    $225–400

  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 39m
    $346–750

  5. Drive 1,352 mi

    1. Drive from Portland to Des Moinescar car 1,352 mi
    24h 30m
    $247–357

  6. Fly to Omaha

    1. Fly from Portland (PWM) to Omaha (OMA)plane plane PWM - OMA
    5h 15m
    $207–843

  7. Fly to The Eastern Iowa Airport

    1. Fly from Portland (PWM) to The Eastern Iowa Airport (CID)plane plane PWM - CID
    5h 35m
    $167–643

  8. Bus, train via Galesburg

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    35h 31m
    $370–810

Portland (PWM) to Des Moines (DSM) flights

Calendar92Weekly Planes
Duration6h 40mAverage Duration
Ticket$209Cheapest Price
See schedules

Questions & Answers

Map of how to get from Maine to Iowa.ExpandLaunch map view
  • Distance: 1,198.6 mi
  • Duration: 4h 56m

What companies run services between Maine, USA and Iowa, USA?

Southwest Airlines, Delta, and two other airlines fly from Portland (PWM) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Portland Public Library to Des Moines via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, Chicago Bus Station, and Des Moines in around 33h 16m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers