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How to get fromMaine to Louisvilleby plane, bus, train, bus (Amtrak, Greyhound, Flixbus), car, or bus (Flixbus, Amtrak)

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There are 6 ways to get from Maine to Louisville by plane, bus, train, bus (Amtrak, Greyhound, Flixbus), car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Portland (PWM) to Louisville International Airport (SDF)plane plane PWM - SDF
    5h 31m
    $187–942

  2. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    28h 55m
    $496–859

  3. Bus via Boston

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    29h 12m
    $215–364

  4. Drive  1,036 mi

    1. Drive from Portland to Louisvillecar car 1,036 mi
    18h 34m
    $190–274

  5. Bus

    1. Take the bus from City of Portland to New York Midtownbus bus
    2. Take the bus from New York Midtown to Cincinnatibus bus
    3. Take the bus from Cincinnati to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    33h 18m
    $198–389

  6. Train, bus (Amtrak)

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    35h 52m
    $637–1,702

Maine to Louisville by bus and train

Calendar7Weekly Services
Duration28h 55mAverage Duration
Ticket$496Cheapest Price
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Comparing Your Travel Options

Map of how to get from Maine to Louisville.ExpandLaunch map view
  • Distance: 894 mi
  • Duration: 5h 31m

What companies run services between Maine, USA and Louisville, KY, USA?

Southwest Airlines, United Airlines, and Delta fly from Portland (PWM) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Portland Public Library to Louisville, KY via Portland, ME, Boston, MA - South Station, Boston, Newark Penn Station, and Indianapolis Union Station in around 29h 12m.

Airlines
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Want to know more about travelling around United States

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