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How to get fromMaine to Mississippiby plane, bus (Amtrak, Flixbus, Greyhound), bus, train, car, or bus (Amtrak, Greyhound)

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There are 7 ways to get from Maine to Mississippi by plane, bus (Amtrak, Flixbus, Greyhound), bus, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Memphis

    best
    1. Fly from Portland (PWM) to Memphis (MEM)plane plane PWM - MEM
    5h 11m
    $255–1,045

  2. Fly to Gulfport-Biloxi Regional Airport

    cheapest
    1. Fly from Portland (PWM) to Gulfport-Biloxi Regional Airport (GPT)plane plane PWM - GPT
    5h 58m
    $185–752

  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonbus bus
    35h 6m
    $318–509

  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksontrain train
    42h 30m
    $593–1,239

  5. Drive 1,500 mi

    1. Drive from Portland to Jacksoncar car 1,500 mi
    25h 41m
    $274–396

  6. Fly to Jackson/Vicksburg

    1. Fly from Portland (PWM) to Jackson/Vicksburg (JAN)plane plane PWM - JAN
    5h 53m
    $186–675

  7. Bus via New York

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from South Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonbus bus
    36h 23m
    $353–579

Maine to Mississippi by bus

Calendar28Weekly Buses
Duration35h 6mAverage Duration
Ticket$318Cheapest Price
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Questions & Answers

Map of how to get from Maine to Mississippi.ExpandLaunch map view
  • Distance: 1,210.2 mi
  • Duration: 5h 11m

What companies run services between Maine, USA and Mississippi, USA?

Southwest Airlines, American Airlines, and Delta fly from Portland (PWM) to Memphis (MEM) every 3 hours. Alternatively, you can take a bus from Portland Public Library to Jackson via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, and Atlanta Bus Station in around 35h 6m.

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