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How to get fromMaine to Mississippiby plane, bus (Amtrak, Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Find Transport to Mississippi

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There are 7 ways to get from Maine to Mississippi by plane, bus (Amtrak, Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Memphis

    best
    1. Fly from Portland (PWM) to Memphis (MEM)plane plane PWM - MEM
    5h 1m
    $264–1,143

  2. Fly to Jackson/Vicksburg

    cheapest
    1. Fly from Portland (PWM) to Jackson/Vicksburg (JAN)plane plane PWM - JAN
    5h 39m
    $183–695

  3. Bus via Boston

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonbus bus
    35h 37m
    $253–404

  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksontrain train
    42h 29m
    $473–1,079

  5. Drive  1,499.9 mi

    1. Drive from Portland to Jacksoncar car 1,499.9 mi
    25h 41m
    $274–396

  6. Fly to Gulfport-Biloxi Regional Airport

    1. Fly from Portland (PWM) to Gulfport-Biloxi Regional Airport (GPT)plane plane PWM - GPT
    6h 11m
    $189–811

  7. Bus

    1. Take the bus from Portland, ME to New York, NYbus bus
    2. Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonbus bus
    36h 57m
    $275–436

Maine to Mississippi by bus

Calendar14Weekly Buses
Duration35h 37mAverage Duration
Ticket$253Cheapest Price
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Comparing Your Travel Options

Map of how to get from Maine to Mississippi.ExpandLaunch map view
  • Distance: 1,210.2 mi
  • Duration: 5h 1m

What companies run services between Maine, USA and Mississippi, USA?

Southwest Airlines, American Airlines, and Delta fly from Portland (PWM) to Memphis (MEM) every 3 hours. Alternatively, you can take a bus from Portland Public Library to Jackson via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, and Atlanta Bus Station in around 35h 37m.

Airlines
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Want to know more about travelling around United States

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Need to know: Greyhound

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