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How to get fromMaine to Sanibel Islandby plane, bus, train, bus (Amtrak, Flixbus, Greyhound), or car

Find Transport to Sanibel Island

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There are 6 ways to get from Maine to Sanibel Island by plane, bus, train, bus (Amtrak, Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Portland (PWM) to Ft. Myers (RSW)plane plane PWM - RSW
    4h 26m
    $238–789
  2. Bus, train

    1. Take the bus from Portland, ME to New York, NYbus bus
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Orlandotrain train
    3. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus
    38h 44m
    $560–1,057
  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    39h 1m
    $309–537
  4. Drive 1,546.7 mi

    1. Drive from Portland to Sanibel Islandcar car 1,546.7 mi
    27h 24m
    $283–408
  5. Bus, train via Washington

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Tampatrain train
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    38h 56m
    $563–1,158
  6. Train, bus (Amtrak)

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Orlandotrain train
    4. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus
    39h 35m
    $580–1,787

Portland (PWM) to Ft. Myers (RSW) flights

Calendar32Weekly Planes
Duration5h 34mAverage Duration
Ticket$162Cheapest Price
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Questions & Answers

What companies run services between Maine, USA and Sanibel Island, FL, USA?

Breeze Airways, Southwest Airlines, and two other airlines fly from Portland (PWM) to Ft. Myers (RSW) 5 times a day. Alternatively, you can take a bus from Portland Public Library to Sanibel Island via Portland, ME, Boston, MA - South Station, Boston, Baltimore Downtown Bus Station, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 39h 1m.

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