Rome2Rio

How to get fromMaine to Winston-Salemby plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

Find Transport to Winston-Salem

See all options

There are 8 ways to get from Maine to Winston-Salem by plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Piedmont Triad International Airport

    best
    1. Fly from Portland (PWM) to Piedmont Triad International Airport (GSO)plane plane PWM - GSO
    5h 18m
    $109–500

  2. Fly Bangor to Piedmont Triad International Airport

    cheapest
    1. Fly from Bangor (BGR) to Piedmont Triad International Airport (GSO)plane plane BGR - GSO
    6h 49m
    $100–454

  3. Bus via New York

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Winston-Salem, NCbus bus Nyc
    19h 37m
    $133–209

  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Lynchburgtrain train
    3. Take the train from Lynchburg to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    20h 58m
    $427–702

  5. Drive  840.1 mi

    1. Drive from Portland to Winston-Salemcar car 840.1 mi
    15h 48m
    $154–222

  6. Fly Portland to Charlotte Douglas International Airport, bus

    1. Fly from Portland (PWM) to Charlotte Douglas International Airport (CLT)plane plane PWM - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 37m
    $169–817

  7. Fly Portland to Raleigh-Durham International Airport, bus

    1. Fly from Portland (PWM) to Raleigh-Durham International Airport (RDU)plane plane PWM - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    6h 31m
    $122–504

  8. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Winston Salem(Trans Center)bus bus
    24h 34m
    $168–279

Maine to Winston-Salem by bus and train

Calendar5Weekly Services
Duration20h 58mAverage Duration
Ticket$427Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Maine to Winston-Salem.ExpandLaunch map view
  • Distance: 751.6 mi
  • Duration: 5h 18m

What companies run services between Maine, USA and Winston-Salem, NC, USA?

United Airlines, American Airlines, and Delta fly from Portland (PWM) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Portland Public Library to Winston-Salem, NC via Portland, ME, Boston, MA - South Station, Boston, NYC Downtown, and New York, NY in around 19h 37m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There