There are 6 ways to get from Mainz, Hauptbahnhof to Brussels by train (Eurostar), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Cologne
best- Take the train from Mainz, Hauptbahnhof to Köln Hbftrain 91 / ...
- Take the train from Köln Hbf to Bruxelles Miditrain 79
4h 27m€55–202Bus
cheapest- Take the bus from Mainz central train station to Brussels-North train stationbus N1310
5h 50m€30–50Drive 363.4 km
- Drive from Mainz, Hauptbahnhof to Brusselscar 363.4 km
3h 36m€69–99Fly to Brussels Airport
- Fly from Frankfurt (FRA) to Brussels Airport (BRU)plane FRA - BRU
3h 41m€82–231Train
- Take the train from Mainz, Hauptbahnhof to Koblenz Hauptbahnhoftrain Re2
- Take the train from Koblenz Hbf to Bruxelles-Nordtrain Nj / ...
6h 58m€72–115Fly to Luxembourg, train
- Fly from Frankfurt (FRA) to Luxembourg (LUX)plane FRA - LUX
- Take the train from Luxembourg to Bruxelles-Luxembourgtrain
6h 26m€145–422
Mainz, Hauptbahnhof to Brussels by train
Comparing Your Travel Options
The cheapest way to get from Mainz, Hauptbahnhof to Brussels is to bus which costs €30 - €50 and takes 5h 50m.
The fastest way to get from Mainz, Hauptbahnhof to Brussels is to drive which takes 3h 36m and costs €65 - €100.
Yes, there is a direct bus departing from Mainz central train station station and arriving at Brussels-North train station station. Services depart once daily, and operate every day. The journey takes approximately 5h 50m.
No, there is no direct train from Mainz, Hauptbahnhof to Brussels. However, there are services departing from Mainz, Hauptbahnhof and arriving at Bruxelles Midi via Köln Hbf. The journey, including transfers, takes approximately 4h 27m.
The distance between Mainz, Hauptbahnhof and Brussels is 401 km. The road distance is 363.4 km.
The best way to get from Mainz, Hauptbahnhof to Brussels without a car is to train via Cologne which takes 4h 27m and costs €55 - €210.
It takes approximately 4h 27m to get from Mainz, Hauptbahnhof to Brussels, including transfers.
Mainz, Hauptbahnhof to Brussels bus services, operated by FlixBus, depart from Mainz central train station.
Mainz, Hauptbahnhof to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz, Hauptbahnhof to Brussels is to train via Cologne which takes 4h 27m and costs €55 - €210. Alternatively, you can bus, which costs €30 - €50 and takes 5h 50m, you could also fly, which costs €80 - €240 and takes 3h 41m.
What companies run services between Mainz, Hauptbahnhof, Germany and Brussels, Belgium?
You can take a train from Mainz, Hauptbahnhof to Bruxelles Midi via Köln Hbf in around 4h 27m. Alternatively, FlixBus operates a bus from Mainz central train station to Brussels-North train station once daily. Tickets cost €30–50 and the journey takes 5h 50m.
- Website
- lufthansa.com
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €35–260
Flights from Frankfurt to Luxembourg
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- €100–340
- Website
- brusselsairlines.com
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €75–120
- Website
- airdolomiti.it
Flights from Frankfurt to Luxembourg
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- €260–340
- Website
- lufthansa-city.com
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €35–260
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 1h 46m
- Frequency
- Every 2 hours
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Köln Hbf to Bruxelles Midi
- Ave. Duration
- 1h 52m
- Frequency
- Every 4 hours
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49-261-98887070
- [email protected]
- Website
- Trans Regio Deutsche Regionalbahn GmbH (MittelrheinBahn)
Train from Mainz, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- €30–45
- Schedules at
- Trans Regio Deutsche Regionalbahn GmbH (MittelrheinBahn)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- €19–40
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Köln Hbf to Bruxelles Midi
- Ave. Duration
- 1h 52m
- Frequency
- 4 times a day
- Estimated price
- €85–140
- Website
- Eurostar
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Köln Hbf to Bruxelles Midi
- Ave. Duration
- 1h 54m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Belgian Railways
Train from Koblenz Hbf to Bruxelles-Nord
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- €55–90
- Website
- Belgian Railways
Train from Luxembourg to Bruxelles-Luxembourg
- Ave. Duration
- 2h 52m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Koblenz Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Every 4 hours
- Estimated price
- €17–24
- Schedules at
- Süwex
- Phone
- +49 6731 999 27-27
- [email protected]
- Website
- vlexx
Train from Mainz, Hauptbahnhof to Koblenz Hauptbahnhof
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- €17–25
- Schedules at
- vlexx
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mainz central train station to Brussels-North train station
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- Flixbus
Want to know more about travelling around Belgium
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Booking & Getting There
Mainz, Hauptbahnhof to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Mainz, Hauptbahnhof to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Köln Hbf station.
Yes, the driving distance between Mainz, Hauptbahnhof to Brussels is 363 km. It takes approximately 3h 36m to drive from Mainz, Hauptbahnhof to Brussels.
Book your Mainz, Hauptbahnhof to Brussels train tickets online with Omio.
Book your Mainz, Hauptbahnhof to Brussels bus tickets online with Omio and FlixBus.
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