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How to get fromMainz, Hauptbahnhof to Brusselsby train, bus, car, or plane

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There are 6 ways to get from Mainz, Hauptbahnhof to Brussels by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Cologne

    best
    1. Take the train from Mainz, Hauptbahnhof to Köln Hbftrain train 55 / ...
    2. Take the train from Köln Hbf to Bruxelles Miditrain train 79
    4h 50m
    €56–309

  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Brussels-North train stationbus bus N1310
    5h 45m
    €30–55

  3. Drive 363.4 km

    1. Drive from Mainz, Hauptbahnhof to Brusselscar car 363.4 km
    3h 36m
    €56–81

  4. Fly to Brussels Airport

    1. Fly from Frankfurt (FRA) to Brussels Airport (BRU)plane plane FRA - BRU
    3h 43m
    €82–256

  5. Train

    1. Take the train from Mainz, Hauptbahnhof to Koblenz Hauptbahnhoftrain train 55 / ...
    2. Take the train from Koblenz Hbf to Bruxelles-Nordtrain train Nj
    7h 2m
    €60–180

  6. Fly to Amsterdam Airport Schiphol, train

    1. Fly from Frankfurt (FRA) to Amsterdam Airport Schiphol (AMS)plane plane FRA - AMS
    2. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    5h 38m
    €180–402

Mainz, Hauptbahnhof to Brussels by train

Calendar91Weekly Trains
Duration4h 50mAverage Duration
Ticket€56Cheapest Price
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Questions & Answers

Map of how to get from Mainz, Hauptbahnhof to Brussels.ExpandLaunch map view
  • Distance: 400.9 km
  • Duration: 4h 50m

What companies run services between Mainz, Hauptbahnhof, Germany and Brussels, Belgium?

You can take a train from Mainz, Hauptbahnhof to Bruxelles Midi via Köln Hbf in around 4h 50m. Alternatively, FlixBus operates a bus from Mainz central train station to Brussels-North train station once daily. Tickets cost €30–55 and the journey takes 5h 45m.

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