There are 13 ways to get from Mainz to Assisi by train, bus, train (Trenitalia), night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the bus from Basel to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
13h 51m€133–301Fly Frankfurt to Fiumicino International Airport, train
cheapest- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
- Take the train from Roma Termini to Assisitrain
9h 9m€71–194Train
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Lambratetrain Ec
- Take the train from Milano Lambrate to Assisitrain Ic
18h 13m€307–542Night train, train
- Take the nighttrain from Mainz Hbf to Innsbruck Hauptbahnhofnighttrain Nj
- Take the nighttrain from Innsbruck Hauptbahnhof to Bologna Centralenighttrain Nj
- Take the train from Bologna Centrale to Assisitrain Ic
21h 51m€95–281Drive 1,128.7 km
- Drive from Mainz to Assisicar 1,128.7 km
10h 45m€183–264Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
19h 57m€149–218Bus via Frankfurt am Main
- Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus N77 / ...
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
21h 53m€112–193Fly Frankfurt to Florence Peretola Airport, train
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Assisitrain
9h 19m€147–360Fly Frankfurt to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Assisitrain
9h 44m€130–338Fly Frankfurt to Raffaello Sanzio Airport, train
- Fly from Frankfurt (FRA) to Raffaello Sanzio Airport (AOI)plane FRA - AOI
- Take the train from Jesi to Folignotrain
10h 58m€169–343Bus to Hahn, fly to Fiumicino International Airport, train
- Take the bus from Mainz, Hauptbahnhof to Hahnbus
- Fly from Hahn (HHN) to Fiumicino International Airport (FCO)plane HHN - FCO
- Take the train from Roma Termini to Assisitrain
10h 11m€75–260Fly Frankfurt to Milan Linate Airport, train
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Milano P.Garibaldi to Perugiatrain
10h 49m€105–293Fly Frankfurt to Venice Marco Polo Airport, train
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
11h 52m€140–330
Mainz to Assisi by train and bus
Comparing Your Travel Options
The cheapest way to get from Mainz to Assisi is to fly and train which costs €70 - €200 and takes 9h 9m.
The fastest way to get from Mainz to Assisi is to fly and train which takes 9h 9m and costs €70 - €200.
No, there is no direct bus from Mainz to Assisi. However, there are services departing from Wiesbaden-Mainz-Kastel Bahnhof and arriving at Assisi via Wiesbaden Gartenfeldstraße P+R and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 19h 57m.
No, there is no direct train from Mainz to Assisi. However, there are services departing from Mainz, Römisches Theater and arriving at Assisi via Frankfurt, Chiasso and Milano Lambrate. The journey, including transfers, takes approximately 18h 13m.
The distance between Mainz and Assisi is 1222 km. The road distance is 1128.7 km.
The best way to get from Mainz to Assisi without a car is to train and bus which takes 13h 51m and costs €130 - €310.
It takes approximately 13h 51m to get from Mainz to Assisi, including transfers.
Mainz to Assisi bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Assisi train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Frankfurt station.
The best way to get from Mainz to Assisi is to train which takes 18h 13m and costs €300 - €550. Alternatively, you can bus, which costs €140 - €220 and takes 19h 57m.
What companies run services between Mainz, Germany and Assisi, Italy?
You can take a train from Mainz, Römisches Theater to Via San Francesco via Frankfurt, Chiasso, Milano Lambrate, Assisi, and Assisi Stazione in around 18h 13m. Alternatively, you can take a bus from Wiesbaden-Mainz-Kastel Bahnhof to Assisi via Wiesbaden Hauptbahnhof, Wiesbaden Gartenfeldstraße P+R, and Florence Villa Constanza Bus Station in around 19h 57m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €110–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €170–550
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €70–130
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- €75–130
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €130–450
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–460
Flights from Frankfurt to Raffaello Sanzio Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €200–650
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–250
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 2h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–420
- Website
- ita-airways.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €110–550
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €70–130
Flights from Frankfurt to Fiumicino International Airport via Milan Linate Airport
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €75–420
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €130–450
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–250
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €160–550
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €140–450
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
- Website
- condor.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 45m
- When
- Friday
- Estimated price
- €70–160
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 10m
- When
- Friday
- Estimated price
- €85–200
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €45–120
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–140
- Website
- volotea.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €70–110
Flights from Frankfurt to Raffaello Sanzio Airport via Olbia
- Ave. Duration
- 6h 30m
- When
- Friday
- Estimated price
- €100–340
- Website
- dat.dk
Flights from Frankfurt to Raffaello Sanzio Airport via Milan Linate Airport
- Ave. Duration
- 4h 5m
- When
- Monday to Friday
- Estimated price
- €60–650
Flights from Frankfurt to Raffaello Sanzio Airport via Fiumicino International Airport
- Ave. Duration
- 6h 15m
- When
- Monday and Friday
- Estimated price
- €100–340
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–350
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 20m
- When
- Monday and Saturday
- Estimated price
- €75–300
- Website
- ryanair.com
Flights from Hahn to Fiumicino International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €40–200
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–100
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Innsbruck Hauptbahnhof
- Ave. Duration
- 9h 3m
- Frequency
- Twice daily
- Estimated price
- €65–130
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €230–380
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Chiasso to Milano Lambrate
- Ave. Duration
- 53 min
- Frequency
- Twice a week
- Estimated price
- €19–35
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Lambrate to Assisi
- Ave. Duration
- 5h 49m
- Frequency
- Once daily
- Estimated price
- €50–95
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Assisi
- Ave. Duration
- 3h 31m
- Frequency
- Once daily
- Estimated price
- €29–55
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €19–35
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Assisi
- Ave. Duration
- 3h 31m
- Frequency
- Once daily
- Estimated price
- €29–55
- Website
- Trenitalia Intercity
Train from Jesi to Foligno
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €19–35
- Website
- Trenitalia Intercity
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Innsbruck Hauptbahnhof
- Ave. Duration
- 9h 18m
- Frequency
- Twice a week
- Estimated price
- €35–110
- Website
- Nightjet
- Sleeper Carriage
- €100–110
- Couchette Carriage
- €65–80
- Seating Carriage
- €35–45
Night train from Innsbruck Hauptbahnhof to Bologna Centrale
- Ave. Duration
- 6h 4m
- Frequency
- Once daily
- Estimated price
- €28–96
- Website
- Nightjet
- Sleeper Carriage
- €95–96
- Couchette Carriage
- €60–70
- Seating Carriage
- €28–34
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 46m
- Frequency
- Every 4 hours
- Estimated price
- €21–29
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Jesi to Foligno
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- €12–17
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 46m
- Frequency
- Every 4 hours
- Estimated price
- €21–29
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Jesi to Foligno
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €14–24
- Website
- Trenitalia Frecce
Train from Milano P.Garibaldi to Perugia
- Ave. Duration
- 3h 42m
- Frequency
- 6 times a week
- Estimated price
- €60–110
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €29–50
- Website
- Italo Treno
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Basel to Florence Villa Constanza Bus Station
- Ave. Duration
- 5h 46m
- Frequency
- Once a week
- Estimated price
- €80–120
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 2m
- Frequency
- Once a week
- Estimated price
- €130–190
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €15–24
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €15–24
- Website
- Flixbus
Bus from Frankfurt central train station to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 40m
- Frequency
- Twice daily
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €15–24
- Website
- Flixbus
- Phone
- +49 (0) 6543 5019-400
- [email protected]
- Website
- Bohr
Bus from Mainz, Hauptbahnhof to Hahn
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €14–16
- Schedules at
- Bohr
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Booking & Getting There
Mainz to Assisi bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Mainz to Assisi train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Chiasso station.
Yes, the driving distance between Mainz to Assisi is 1129 km. It takes approximately 10h 45m to drive from Mainz to Assisi.
Book your Mainz to Assisi bus tickets online with Omio.
There are 2396+ hotels available in Assisi.










































