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How to get fromMainz to Brindisiby plane, train (Trenitalia), bus, train, night train, car, or car train

Find Transport to Brindisi

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There are 7 ways to get from Mainz to Brindisi by plane, train (Trenitalia), bus, train, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Frankfurt (FRA) to Brindisi Airport (BDS)plane plane FRA - BDS
    4h 28m
    €101–265

  2. Train

    1. Take the train from Frankfurt to Basel SBBtrain train 43
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Mediopadana R.Emiliatrain train
    5. Take the train from Reggio Emilia Av to Brindisitrain train Fr
    19h 8m
    €214–544

  3. Bus via Mannheim

    1. Take the bus from Mainz, Stadtpark to Worms, Hauptbahnhofbus bus S5 / ...
    2. Take the bus from Ludwigshafen ZOB to Baribus bus
    3. Take the bus from Bari Largo Sorrentino to Brindisi Strada Stratale Via Appiabus bus
    22h 58m
    €155–242

  4. Train, night train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 47 / ...
    3. Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    4. Take the train from Venezia Mestre to Brindisitrain train Fr
    24h 32m
    €190–445

  5. Bus

    1. Take the bus from Frankfurt central train station to Baribus bus N422
    2. Take the bus from Bari FS Park - Via Capruzzi to Brindisi Istituto Professionale Falconebus bus Itabus
    27h 32m
    €153–271

  6. Drive  1,652.5 km

    1. Drive from Mainz to Brindisicar car 1,652.5 km
    15h 12m
    €268–387

  7. Drive, car train

    1. Drive from Mainz to Fuldacar car
    2. Take the cartrain from Fulda to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Brindisicar car
    21h 23m
    €296–420

Mainz to Brindisi by train and night train

Calendar9Weekly Services
Duration24h 32mAverage Duration
Ticket€190Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Brindisi.ExpandLaunch map view
  • Distance: 1,299.6 km
  • Duration: 4h 28m

What companies run services between Mainz, Germany and Brindisi, Italy?

Airbus France, Lufthansa, and three other airlines fly from Frankfurt (FRA) to Brindisi Airport (BDS) twice daily. Alternatively, you can take a train from Mainz, Römisches Theater to Brindisi via Frankfurt, Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 19h 8m.

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