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How to get fromMainz to Brindisiby plane, train (Trenitalia), bus, train, night train, car, or car train

Find Transport to Brindisi

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There are 8 ways to get from Mainz to Brindisi by plane, train (Trenitalia), bus, train, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt

    best
    1. Fly from Frankfurt (FRA) to Brindisi Airport (BDS)plane plane FRA - BDS
    4h 28m
    €99–260

  2. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Reggio Emilia Avtrain train Fr
    6. Take the train from Reggio Emilia Av to Brindisitrain train Fr
    18h 21m
    €205–517

  3. Bus via Mannheim

    1. Take the bus from Mainz, Stadtpark to Worms, Hauptbahnhofbus bus S5 / ...
    2. Take the bus from Ludwigshafen ZOB to Baribus bus
    3. Take the bus from Bari Largo Sorrentino to Brindisi Strada Stratale Via Appiabus bus
    22h 58m
    €154–237

  4. Train, night train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 47 / ...
    3. Take the nighttrain from Stuttgart Hbf to Padovanighttrain night train Nj
    4. Take the train from Padova to Brindisitrain train Fr
    26h 13m
    €192–441

  5. Train to Stuttgart Airport, fly

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Brindisi Airport (BDS)plane plane STR - BDS
    6h 12m
    €132–340

  6. Bus

    1. Take the bus from Frankfurt central train station to Baribus bus N422
    2. Take the bus from Bari to Brindisibus bus FlixBus N436 / ...
    28h 23m
    €148–258

  7. Drive  1,652.5 km

    1. Drive from Mainz to Brindisicar car 1,652.5 km
    15h 12m
    €268–386

  8. Drive, car train

    1. Drive from Mainz to Fuldacar car
    2. Take the cartrain from Fulda to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Brindisicar car
    21h 40m
    €296–420

Mainz to Brindisi by train

Calendar73Weekly Trains
Duration18h 21mAverage Duration
Ticket€205Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Brindisi.ExpandLaunch map view
  • Distance: 1,299.6 km
  • Duration: 4h 28m

What companies run services between Mainz, Germany and Brindisi, Italy?

Airbus France, Lufthansa, and two other airlines fly from Frankfurt (FRA) to Brindisi Airport (BDS) once daily. Alternatively, you can take a train from Mainz, Hauptbahnhof to Brindisi via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 18h 21m.

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