There are 11 ways to get from Mainz to Brno by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Vienna International Airport, train
best- Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane FRA - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
6h 37mKč 1,935–5,390Bus via Prague
cheapest- Take the bus from Mainz central train station to Praguebus N1310
- Take the bus from Praha, Hlavní Nádraží to Brnobus N360 / ...
12hKč 1,641–2,413Train via Dresden
- Take the train from Frankfurt to Dresden Hauptbahnhoftrain 50
- Take the train from Dresden Hbf to Brno hl.n.train rj 175
12h 7mKč 2,673–6,155Drive 743.5 km
- Drive from Mainz to Brnocar 743.5 km
6h 11mKč 2,873–4,149Fly Frankfurt to Václav Havel Airport Prague, train
- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the train from Praha hl.n. to Brno hl.n.train
7h 43mKč 1,778–3,820Fly Frankfurt to Dresden Airport, train
- Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane FRA - DRS
- Take the train from Dresden-Neustadt to Brno hl.n.train
9h 6mKč 3,665–8,640Train to Stuttgart Airport, fly to Vienna International Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane STR - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8h 26mKč 2,755–8,293Train to Cologne Bonn Airport, fly to Vienna International Airport, train
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Vienna International Airport (VIE)plane CGN - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8h 27mKč 2,180–8,390Fly Frankfurt to Linz Airport, train
- Fly from Frankfurt (FRA) to Linz Airport (LNZ)plane FRA - LNZ
- Take the train from Linz/Donau Hbf to Wien Hbftrain
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8h 44mKč 2,992–6,952Train
- Take the train from Frankfurt to Praha Hlavní nádražítrain Drf
- Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain Re / ...
15h 16mBus
- Take the bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádražíbus Ivano-Frankivsk
20h 59mKč 3,473–4,305
Mainz to Brno by bus
Comparing Your Travel Options
The cheapest way to get from Mainz to Brno is to bus via Prague which costs 1 600 Kč - 2 500 Kč and takes 12h.
The fastest way to get from Mainz to Brno is to drive which takes 6h 11m and costs 2 800 Kč - 4 200 Kč.
No, there is no direct bus from Mainz station to Brno. However, there are services departing from Mainz central train station and arriving at Brno via Praha, Hlavní Nádraží. The journey, including transfers, takes approximately 12h.
No, there is no direct train from Mainz to Brno. However, there are services departing from Mainz, Römisches Theater and arriving at Brno hl.n. via Frankfurt and Dresden Hbf. The journey, including transfers, takes approximately 12h 7m.
The distance between Mainz and Brno is 812 km. The road distance is 743.5 km.
The best way to get from Mainz to Brno without a car is to bus via Prague which takes 12h and costs 1 600 Kč - 2 500 Kč.
It takes approximately 6h 37m to get from Mainz to Brno, including transfers.
Mainz to Brno bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Brno train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Brno is to bus via Prague which takes 12h and costs 1 600 Kč - 2 500 Kč. Alternatively, you can train via Dresden, which costs 2 600 Kč - 6 500 Kč and takes 12h 7m.
What companies run services between Mainz, Germany and Brno, Czechia?
You can take a bus from Mainz central train station to Brno via Prague and Praha, Hlavní Nádraží in around 12h. Alternatively, you can take a train from Mainz, Römisches Theater to Brno hl.n. via Frankfurt, Dresden Hauptbahnhof, and Dresden Hbf in around 12h 7m.
- Website
- lufthansa.com
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- Kč 1,700–4,600
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- Kč 1,400–10,000
Flights from Frankfurt to Václav Havel Airport Prague via Munich
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- Kč 1,400–3,400
Flights from Frankfurt to Dresden Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,300–9,500
Flights from Frankfurt to Dresden Airport via Munich
- Ave. Duration
- 2h 40m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- Kč 2,400–7,000
Flights from Stuttgart Airport to Vienna International Airport via Munich
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- Kč 1,600–4,700
Flights from Cologne Bonn Airport to Vienna International Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday, Friday, Sunday, Thursday, and Saturday
- Estimated price
- Kč 2,300–5,500
Flights from Frankfurt to Linz Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 2,100–3,700
- Website
- austrian.com
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- Kč 1,700–4,600
Flights from Stuttgart Airport to Vienna International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- Kč 1,600–4,700
Flights from Cologne Bonn Airport to Vienna International Airport
- Ave. Duration
- 1h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 1,500–5,000
- Website
- condor.com
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- Kč 1,600–3,200
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,300–2,700
- Website
- eurowings.com
Flights from Stuttgart Airport to Vienna International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 1,700–4,600
Flights from Cologne Bonn Airport to Vienna International Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 1,800–5,000
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Vienna International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 1,200–4,800
- Website
- dat.dk
Flights from Frankfurt to Linz Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 2,100–3,700
- Website
- swiss.com
Flights from Stuttgart Airport to Vienna International Airport via Zurich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- Kč 1,600–4,700
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 3,200–10,000
- Website
- lufthansa-city.com
Flights from Frankfurt to Dresden Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,300–9,500
- Phone
- +43 (0)5 1717
- Website
- Railjet
Train from Wien Hbf to Brno Hlavni Nadrazi
- *
- Kč 600–950
Train from Wien Hbf to Brno Hlavni Nadrazi
- *
- Kč 600–950
Train from Wien Hbf to Brno Hlavni Nadrazi
- *
- Kč 600–950
Train from Linz/Donau Hbf to Wien Hbf
- *
- Kč 700–1,100
Train from Wien Hbf to Brno Hlavni Nadrazi
- *
- Kč 600–950
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- Kč 170–290
- Website
- RegioJet
Train from Praha hl.n. to Brno hl.n.
- Ave. Duration
- 2h 39m
- Frequency
- 4 times a day
- Estimated price
- Kč 300–490
- Website
- RegioJet
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- Kč 170–290
- Website
- RegioJet
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- Kč 170–290
- Website
- RegioJet
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- Kč 170–290
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 39m
- Frequency
- Every 3 hours
- Estimated price
- Kč 300–490
- Website
- RegioJet
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Dresden Hauptbahnhof
- Ave. Duration
- 4h 25m
- Frequency
- Every 3 hours
- Estimated price
- Kč 2,000–4,500
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- Kč 750–1,700
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- Kč 600–1,400
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Linz/Donau Hbf to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- 3 times a week
- Estimated price
- Kč 750–1,700
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +421 24 48 58 188
- [email protected]
- Website
- Railways of Slovak Republic (ZSSK)
Train from Dresden Hbf to Brno hl.n.
- Ave. Duration
- 5h 4m
- Frequency
- Twice daily
- Estimated price
- Kč 500–950
- Website
- Railways of Slovak Republic (ZSSK)
Train from Praha hl.n. to Brno hl.n.
- Ave. Duration
- 2h 36m
- Frequency
- Every 4 hours
- Estimated price
- Kč 300–550
- Website
- Railways of Slovak Republic (ZSSK)
Train from Dresden-Neustadt to Brno hl.n.
- Ave. Duration
- 5h 12m
- Frequency
- Twice daily
- Estimated price
- Kč 500–950
- Website
- Railways of Slovak Republic (ZSSK)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- Kč 380–750
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 51 min
- Frequency
- 3 times a week
- Estimated price
- Kč 600–950
- Website
- Belgian Railways
- Phone
- +43 (0) 5 1717
- Website
- ÖBB Intercity
Train from Linz/Donau Hbf to Wien Hbf
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- Kč 490–900
- Website
- ÖBB Intercity
- Website
- ÖBB Intercity
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Linz/Donau Hbf to Wien Hbf
- Ave. Duration
- 1h 19m
- Frequency
- Twice daily
- Estimated price
- Kč 1,000–1,200
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 38m
- Frequency
- 4 times a day
- Estimated price
- Kč 1,400–1,700
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Website
- LEO Express
Train from Frankfurt to Praha Hlavní nádraží
- Ave. Duration
- 10h 28m
- Frequency
- 3 times a week
- Schedules at
- LEO Express
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- Kč 550–850
- Website
- Czech Railways (ČD)
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mainz central train station to Prague
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- Kč 1,200–1,800
- Website
- Flixbus
Bus from Praha, Hlavní Nádraží to Brno
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- Kč 440–650
- Website
- Flixbus
- Phone
- +38 098-888-11-08
- [email protected]
- Website
- Grand Bus
Bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádraží
- Ave. Duration
- 19h 21m
- Frequency
- Once daily
- Estimated price
- Kč 3,300–3,600
- Website
- Grand Bus
Want to know more about travelling around Czechia
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Booking & Getting There
Mainz to Brno bus services, operated by FlixBus, arrive at Prague station.
Mainz to Brno train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Dresden Hauptbahnhof station.
Yes, the driving distance between Mainz to Brno is 744 km. It takes approximately 6h 11m to drive from Mainz to Brno.
Book your Mainz to Brno train tickets online with Omio.
Book your Mainz to Brno bus tickets online with Omio and FlixBus.
There are 765+ hotels available in Brno.
















































