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How to get fromMainz to Karlovy Varyby train, bus, car, or plane

Find Transport to Karlovy Vary

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There are 6 ways to get from Mainz to Karlovy Vary by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mainz, Hauptbahnhof to Nürnberg Hbftrain train 91 / ...
    2. Take the train from Nürnberg Hbf to Chebtrain train
    3. Take the train from Cheb to Karlovy Varytrain train Re / ...
    6h 44m
    Kč 1,558–2,901

  2. Bus

    cheapest
    1. Take the bus from Frankfurt central train station to Karlovy Varybus bus 068
    8h 40m
    Kč 882–1,420

  3. Drive  382 km

    1. Drive from Mainz to Karlovy Varycar car 382 km
    4h 4m
    Kč 1,731–2,501

  4. Fly to Václav Havel Airport Prague, bus

    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    2. Take the bus from Prague Airport Terminal 1/2 to Karlovy Vary Trznice Bus Stationbus bus
    5h 52m
    Kč 1,552–3,483

  5. Train via Frankfurt am Main

    1. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    2. Take the train from Nürnberg Hbf to Chebtrain train
    3. Take the train from Cheb to Karlovy Varytrain train Re / ...
    7h 3m
    Kč 1,474–3,021

  6. Fly to Nuremberg Airport, train

    1. Fly from Frankfurt (FRA) to Nuremberg Airport (NUE)plane plane FRA - NUE
    2. Take the train from Nürnberg Hbf to Chebtrain train
    3. Take the train from Cheb to Karlovy Varytrain train
    6h 25m
    Kč 2,952–4,953

Mainz to Karlovy Vary by train

Calendar48Weekly Trains
Duration6h 44mAverage Duration
TicketKč 1,558Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Karlovy Vary.ExpandLaunch map view
  • Distance: 462.2 km
  • Duration: 6h 44m

What companies run services between Mainz, Germany and Karlovy Vary, Czechia?

You can take a train from Mainz, Hauptbahnhof to Karlovy Vary via Nürnberg Hbf and Cheb in around 6h 44m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Karlovy Vary once daily. Tickets cost Kč 800–1,300 and the journey takes 6h 55m.

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