There are 6 ways to get from Mainz to Karlovy Vary by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Frankfurt to Nürnberg Hbftrain 41 / ...
- Take the train from Nürnberg Hbf to Chebtrain
- Take the train from Cheb to Karlovy Varytrain Re / ...
6h 56mKč 1,474–2,922Bus
cheapest- Take the bus from Mainz central train station to Bayreuth central train stationbus N1366
- Take the bus from Bayreuth central train station to Karlovy Varybus 068
8h 15mKč 925–1,365Night train, train
- Take the nighttrain from Mainz Hbf to Nuernberg Hbfnighttrain Nj
- Take the train from Nürnberg Hbf to Chebtrain
- Take the train from Cheb to Karlovy Varytrain Re / ...
7h 9mKč 1,093–3,011Drive 382 km
- Drive from Mainz to Karlovy Varycar 382 km
4h 4mKč 1,727–2,494Fly to Václav Havel Airport Prague, bus
- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the bus from Prague Airport Terminal 1/2 to Karlovy Vary Trznice Bus Stationbus
5h 56mKč 1,552–3,484Fly to Nuremberg Airport, train
- Fly from Frankfurt (FRA) to Nuremberg Airport (NUE)plane FRA - NUE
- Take the train from Nürnberg Hbf to Chebtrain
- Take the train from Cheb to Karlovy Varytrain
6h 18mKč 2,952–4,754
Mainz to Karlovy Vary by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Karlovy Vary is to bus which costs 900 Kč - 1 400 Kč and takes 8h 15m.
The fastest way to get from Mainz to Karlovy Vary is to drive which takes 4h 4m and costs 1 700 Kč - 2 500 Kč.
No, there is no direct bus from Mainz station to Karlovy Vary. However, there are services departing from Mainz central train station and arriving at Karlovy Vary via Bayreuth central train station. The journey, including transfers, takes approximately 8h 15m.
No, there is no direct train from Mainz to Karlovy Vary. However, there are services departing from Mainz, Römisches Theater and arriving at Karlovy Vary via Frankfurt, Nürnberg Hbf and Cheb. The journey, including transfers, takes approximately 6h 56m.
The distance between Mainz and Karlovy Vary is 463 km. The road distance is 382 km.
The best way to get from Mainz to Karlovy Vary without a car is to train which takes 6h 56m and costs 1 400 Kč - 3 000 Kč.
It takes approximately 6h 56m to get from Mainz to Karlovy Vary, including transfers.
Mainz to Karlovy Vary bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Karlovy Vary train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Karlovy Vary is to train which takes 6h 56m and costs 1 400 Kč - 3 000 Kč. Alternatively, you can bus, which costs 900 Kč - 1 400 Kč and takes 8h 15m.
What companies run services between Mainz, Germany and Karlovy Vary, Czechia?
You can take a train from Mainz, Römisches Theater to Karlovy Vary via Frankfurt, Nürnberg Hbf, and Cheb in around 6h 56m. Alternatively, you can take a bus from Mainz central train station to Karlovy Vary via Bayreuth central train station in around 8h 15m.
- Website
- lufthansa.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- Kč 1,400–11,000
Flights from Frankfurt to Václav Havel Airport Prague via Munich
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- Kč 1,400–3,400
Flights from Frankfurt to Nuremberg Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- Kč 2,300–3,500
- Website
- condor.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,300–2,800
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 3,500–11,000
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Nürnberg Hbf
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- Kč 850–1,800
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Nürnberg Hbf to Cheb
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- Kč 410–600
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Nürnberg Hbf to Cheb
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- Kč 410–600
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Nürnberg Hbf to Cheb
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- Kč 410–600
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Cheb to Karlovy Vary
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 110–170
- Website
- Czech Railways (ČD)
Train from Cheb to Karlovy Vary
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 110–170
- Website
- Czech Railways (ČD)
Train from Cheb to Karlovy Vary
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 110–170
- Website
- Czech Railways (ČD)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Nuernberg Hbf
- Ave. Duration
- 3h 17m
- Frequency
- 5 times a day
- Estimated price
- Kč 550–2,300
- Website
- Nightjet
- Sleeper Carriage
- Kč 2,100–2,300
- Couchette Carriage
- Kč 1,300–1,600
- Seating Carriage
- Kč 550–700
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Nuernberg Hbf
- Ave. Duration
- 3h 17m
- Frequency
- 5 times a day
- Estimated price
- Kč 700–1,300
- Website
- Nederlandse Spoorwegen (NS)
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mainz central train station to Bayreuth central train station
- Ave. Duration
- 5h 15m
- Frequency
- 5 times a week
- Estimated price
- Kč 650–1,000
- Website
- Flixbus
Bus from Bayreuth central train station to Karlovy Vary
- Ave. Duration
- 2h
- Frequency
- 5 times a week
- Estimated price
- Kč 260–390
- Website
- Flixbus
Bus from Prague Airport Terminal 1/2 to Karlovy Vary Trznice Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- Kč 250–380
- Website
- Flixbus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Prague Airport Terminal 1/2 to Karlovy Vary Trznice Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 2 hours
- Estimated price
- Kč 180–300
- Website
- RegioJet
Want to know more about travelling around Czechia
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Booking & Getting There
Mainz to Karlovy Vary bus services, operated by FlixBus, arrive at Bayreuth central train station.
Mainz to Karlovy Vary train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Nürnberg Hbf station.
Yes, the driving distance between Mainz to Karlovy Vary is 382 km. It takes approximately 4h 4m to drive from Mainz to Karlovy Vary.
Book your Mainz to Karlovy Vary train tickets online with Omio and 12go.asia.
Book your Mainz to Karlovy Vary bus tickets online with Omio and FlixBus.
There are 1494+ hotels available in Karlovy Vary.



























