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How to get fromMainz to Karlovy Varyby train, bus, car, or plane

Find Transport to Karlovy Vary

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There are 6 ways to get from Mainz to Karlovy Vary by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mainz, Hauptbahnhof to Nürnberg Hbftrain train 91 / ...
    2. Take the train from Nürnberg Hbf to Chebtrain train
    3. Take the train from Cheb to Karlovy Varytrain train Re / ...
    6h 44m
    Kč 1,856–5,461
  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Bayreuth central train stationbus bus N1366
    2. Take the bus from Bayreuth central train station to Karlovy Varybus bus 068 / ...
    8h 15m
    Kč 822–1,321
  3. Drive  382 km

    1. Drive from Mainz to Karlovy Varycar car 382 km
    4h 4m
    Kč 1,437–2,076
  4. Fly to Václav Havel Airport Prague, bus

    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    2. Take the bus from Prague Airport Terminal 1/2 to Karlovy Vary Trznice Bus Stationbus bus
    5h 53m
    Kč 1,593–3,273
  5. Train via Frankfurt am Main

    1. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    2. Take the train from Nürnberg Hbf to Chebtrain train
    3. Take the train from Cheb to Karlovy Varytrain train Re / ...
    7h 2m
    Kč 1,799–5,212
  6. Fly to Nuremberg Airport, train

    1. Fly from Frankfurt (FRA) to Nuremberg Airport (NUE)plane plane FRA - NUE
    2. Take the train from Nürnberg Hbf to Chebtrain train
    3. Take the train from Cheb to Karlovy Varytrain train
    6h 24m
    Kč 3,163–5,343

Mainz to Karlovy Vary by train

Calendar48Weekly Trains
Duration6h 44mAverage Duration
TicketKč 1,856Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Karlovy Vary, Czechia?

You can take a train from Mainz, Hauptbahnhof to Karlovy Vary via Nürnberg Hbf and Cheb in around 6h 44m. Alternatively, you can take a bus from Mainz central train station to Karlovy Vary via Bayreuth central train station in around 8h 15m.

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Bus operators

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