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How to get fromMainz to Lyonby plane, train (TGV, Trenitalia), train, bus, car, or train (TGV)

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There are 6 ways to get from Mainz to Lyon by plane, train (TGV, Trenitalia), train, bus, car, or train (TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    4h 29m
    €131–346

  2. Train, bus

    cheapest
    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3 / ...
    2. Take the bus from Saarbrücken bus station to Lyonbus bus N235
    10h 45m
    €74–111

  3. Train via Paris

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the train from Saarbrücken Hbf to Paris l'Esttrain train 82
    3. Take the train from Paris Gare De Lyon to Lyon Part Dieutrain train Tgv
    7h 48m
    €145–293

  4. Drive  652.8 km

    1. Drive from Mainz to Lyoncar car 652.8 km
    6h 2m
    €105–152

  5. Train

    1. Take the train from Mainz, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train Re4
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    8h 36m
    €114–291

  6. Bus

    1. Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny Abus bus
    11h 55m
    €98–125

Mainz to Lyon by train and foot

Calendar26Weekly Services
Duration7h 48mAverage Duration
Ticket€145Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Lyon.ExpandLaunch map view
  • Distance: 594.8 km
  • Duration: 4h 29m

What companies run services between Mainz, Germany and Lyon, France?

Lufthansa, Airbus France, and three other airlines fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) every 4 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Lyon Part Dieu via Saarbrücken Hbf, Paris l'Est, Paris Nord, and Paris Gare De Lyon in around 7h 48m.

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