There are 10 ways to get from Mainz to Rome by plane, train, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Fiumicino International Airport
best- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
4h 50m€54–161Train
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
12h 48m€145–442Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Roma Prenestina A1bus
18h 56m€154–214Train, night train
- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the nighttrain from Muenchen Hbf to Roma Tiburtinanighttrain Nj
19h 22m€101–315Train to Stuttgart Airport, fly to Fiumicino International Airport
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
6h 29m€106–239Fly Frankfurt to Florence Peretola Airport, train
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Roma Terminitrain
6h 9m€155–372Train to Cologne Bonn Airport, fly to Fiumicino International Airport
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane CGN - FCO
6h 34m€97–312Fly Frankfurt to Naples Airport, train
- Fly from Frankfurt (FRA) to Naples Airport (NAP)plane FRA - NAP
- Take the train from Napoli to Roma Terminitrain
6h 24m€126–335Bus via Frankfurt am Main
- Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus N77
21h 43m€118–206Drive 1,231.5 km
- Drive from Mainz to Romecar 1,231.5 km
11h 28m€199–287
Mainz to Rome by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Rome is to fly which costs €50 - €170 and takes 4h 50m.
The fastest way to get from Mainz to Rome is to fly which takes 4h 50m and costs €50 - €170.
No, there is no direct bus from Mainz to Rome. However, there are services departing from Wiesbaden-Mainz-Kastel Bahnhof and arriving at Roma Prenestina A1 via Wiesbaden Gartenfeldstraße P+R. The journey, including transfers, takes approximately 18h 56m.
No, there is no direct train from Mainz to Rome. However, there are services departing from Mainz, Hauptbahnhof and arriving at Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano and Milano Centrale. The journey, including transfers, takes approximately 12h 48m.
The distance between Mainz and Rome is 1019 km. The road distance is 1231.5 km.
The best way to get from Mainz to Rome without a car is to train which takes 12h 48m and costs €140 - €450.
It takes approximately 4h 50m to get from Mainz to Rome, including transfers.
Mainz to Rome bus services, operated by Onebus, depart from Wiesbaden Gartenfeldstraße P+R station.
Mainz to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Rome is to fly which takes 4h 50m and costs €50 - €170. Alternatively, you can train, which costs €140 - €450 and takes 12h 48m, you could also bus, which costs €150 - €220 and takes 18h 56m.
What companies run services between Mainz, Germany and Rome, Italy?
easyJet, ITA Airways, and two other airlines fly from Frankfurt (FRA) to Fiumicino International Airport (FCO) hourly. Alternatively, you can take a train from Mainz, Hauptbahnhof to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 12h 48m.
- Website
- lufthansa.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–120
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €65–300
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €120–600
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €170–650
Flights from Cologne Bonn Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- €50–330
Flights from Frankfurt to Naples Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €100–380
Flights from Frankfurt to Naples Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €55–380
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €75–150
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- €27–55
- Website
- Deutsche Bahn Intercity (DB IC)
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- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Roma Prenestina A1
- Ave. Duration
- 17h 36m
- Frequency
- Once a week
- Estimated price
- €150–210
- Website
- Onebus
Want to know more about travelling around Italy
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Booking & Getting There
Mainz to Rome bus services, operated by Onebus, arrive at Roma Prenestina A1 station.
Mainz to Rome train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Rome is 1232 km. It takes approximately 11h 28m to drive from Mainz to Rome.
Book your Mainz to Rome train tickets online with Omio.
Book your Mainz to Rome bus tickets online with Omio.
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