Rome2Rio

How to get fromMainz to Romeby plane, train, bus, night train, or car

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There are 9 ways to get from Mainz to Rome by plane, train, bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Fiumicino International Airport

    best
    1. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    4h 45m
    €53–156

  2. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Roma Terminitrain train
    12h 34m
    €153–463

  3. Bus

    1. Take the bus from Wiesbaden Gartenfeldstraße P+R to Roma Prenestina A1bus bus
    18h 52m
    €154–214

  4. Train, night train

    1. Take the train from Frankfurt to München Hbftrain train 41 / ...
    2. Take the nighttrain from Muenchen Hbf to Roma Tiburtinanighttrain night train Nj
    19h 31m
    €127–319

  5. Bus to Hahn, fly to Fiumicino International Airport

    1. Take the bus from Mainz, Hauptbahnhof to Hahnbus bus
    2. Fly from Hahn (HHN) to Fiumicino International Airport (FCO)plane plane HHN - FCO
    5h 47m
    €57–222

  6. Train to Stuttgart Airport, fly to Fiumicino International Airport

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    6h 29m
    €107–248

  7. Fly Frankfurt to Florence Peretola Airport, train

    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    6h 5m
    €155–387

  8. Bus via Frankfurt am Main

    1. Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus bus N77
    21h 43m
    €117–209

  9. Drive  1,231.5 km

    1. Drive from Mainz to Romecar car 1,231.5 km
    11h 28m
    €200–288

Mainz to Rome by train and night train

Calendar12Weekly Services
Duration19h 31mAverage Duration
Ticket€127Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Rome.ExpandLaunch map view
  • Distance: 1,018.9 km
  • Duration: 4h 45m

What companies run services between Mainz, Germany and Rome, Italy?

easyJet, ITA Airways, and three other airlines fly from Frankfurt (FRA) to Fiumicino International Airport (FCO) every 2 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 12h 34m.

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