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How to get fromMainz to Tuscanyby plane, train (Trenitalia), bus, train, night train, or car

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There are 8 ways to get from Mainz to Tuscany by plane, train (Trenitalia), bus, train, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    4h 23m
    €128–284

  2. Bus via Frankfurt am Main

    cheapest
    1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus bus N77 / ...
    18h 49m
    €86–146

  3. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    11h 30m
    €113–659

  4. Bus

    1. Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus bus
    16h 46m
    €136–196

  5. Train, night train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 47 / ...
    3. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    4. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    18h 7m
    €100–293

  6. Fly to Pisa International Airport

    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    3h 58m
    €106–252

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4h 50m
    €111–279

  8. Drive 957.9 km

    1. Drive from Mainz to Florencecar car 957.9 km
    9h 3m
    €152–219

Mainz to Tuscany by train

Calendar76Weekly Trains
Duration11h 30mAverage Duration
Ticket€113Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Tuscany.ExpandLaunch map view
  • Distance: 753.8 km
  • Duration: 4h 23m

What companies run services between Mainz, Germany and Tuscany, Italy?

Lufthansa, Air Dolomiti, and two other airlines fly from Frankfurt (FRA) to Florence Peretola Airport (FLR) every 2 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Firenze S.M.N. via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 11h 30m.

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