How to get fromManaus to Panamaby plane, bus, ferry, or car

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There are 4 ways to get from Manaus to Panama by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Tocumen International Airport
best
1. Fly from Manaus (MAO) to Tocumen International Airport (PTY)plane MAO - PTY
4h 46m
$280–852
Fly to David
cheapest
1. Fly from Manaus (MAO) to David (DAV)plane MAO - DAV
6h 54m
$233–916
Bus, ferry, drive
1. Take the bus from Manaus to Puerto la Cruzbus
2. Take the bus from Puerto La Cruz to Terminal Expresos Los Llanos San Cristobalbus
3. Take the bus from Terminal San Cristóbal to Terminal Cúcutabus
4. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
5. Take the ferry from Cartagena to Portobeloferry
6. Drive from Portobelo to Panama Citycar
10d 17h
$964–1,042
Bus, ferry, drive via Mérida
1. Take the bus from Manaus to Puerto la Cruzbus
2. Take the bus from Puerto La Cruz to Terminal Jose Antonio Paredesbus
3. Take the bus from Terminal Jose Antonio Paredes to Ureñabus
4. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
5. Take the ferry from Cartagena to Portobeloferry
6. Drive from Portobelo to Panama Citycar
11d 7h
$967–1,053

Manaus (MAO) to Tocumen International Airport (PTY) flights

11Weekly Planes

4h 56mAverage Duration

$139Cheapest Price

Questions & Answers

Map of how to get from Manaus to Panama.

Launch map view

Distance: 2,564.1 km
Duration: 4h 46m

What companies run services between Manaus, Brazil and Panama?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Manaus (MAO) to Tocumen International Airport (PTY) twice daily.

Airlines

Bus operators

Ferry operators

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Panama City, Panama(opens in a new window)

Panama City, also known as Panama (or Panamá in Spanish), is the capital and largest city of Panama. It has a total population of 1,938,000, with over 1,500,000 in its urban area. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for banking and commerce.

Places to stay in Panama City

Plaza Paitilla Inn(Opens in a new window)

8.9Fabulous

Ramada Plaza by Wyndham Panama Punta Pacifica(Opens in a new window)

9.2Superb

Megapolis Hotel Panama(Opens in a new window)

8.5Very Good

Global Hotel Panama(Opens in a new window)

8.6Fabulous

Rome2Rio makes travelling from Manaus to Panama easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Manaus to Panama right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.