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How to get fromManaus to Panamaby plane, bus, ferry, or car

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There are 4 ways to get from Manaus to Panama by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tocumen International Airport

    best
    1. Fly from Manaus (MAO) to Tocumen International Airport (PTY)plane plane MAO - PTY
    4h 39m
    $280–852

  2. Fly to David

    cheapest
    1. Fly from Manaus (MAO) to David (DAV)plane plane MAO - DAV
    6h 51m
    $223–966

  3. Bus, ferry, drive

    1. Take the bus from Manaus to Puerto la Cruzbus bus
    2. Take the bus from Puerto La Cruz to Terminal Expresos Los Llanos San Cristobalbus bus
    3. Take the bus from Terminal San Cristóbal to Terminal Cúcutabus bus
    4. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus bus
    5. Take the ferry from Cartagena to Portobeloferry ferry
    6. Drive from Portobelo to Panama Citycar car
    10d 17h
    $964–1,042

  4. Bus, ferry, drive via Mérida

    1. Take the bus from Manaus to Puerto la Cruzbus bus
    2. Take the bus from Puerto La Cruz to Terminal Jose Antonio Paredesbus bus
    3. Take the bus from Terminal Jose Antonio Paredes to Ureñabus bus
    4. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus bus
    5. Take the ferry from Cartagena to Portobeloferry ferry
    6. Drive from Portobelo to Panama Citycar car
    11d 7h
    $967–1,053

Manaus (MAO) to Tocumen International Airport (PTY) flights

Calendar11Weekly Planes
Duration4h 53mAverage Duration
Ticket$127Cheapest Price
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Comparing Your Travel Options

Map of how to get from Manaus to Panama.ExpandLaunch map view
  • Distance: 2,564.1 km
  • Duration: 4h 39m

What companies run services between Manaus, Brazil and Panama?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Manaus (MAO) to Tocumen International Airport (PTY) twice daily.

Airlines
Bus operators
Ferry operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Heading to Europe? Read this before you buy a Eurail Pass, The beginner’s guide to the 2018 World Nomad Games, and Which London airport should I choose? - to help you get the most out of your next trip.